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Monday, February 13, 2023

Hillstream, Applied Biomedical in Deal on HER2 and HER3 Cancer Treatments

 HER2 and HER3 Conformational Domain Bridging Epitopes in Antibodies via an Exclusive Option Allows Hillstream BioPharma to Develop Proprietary Multi-format Biologics (bispecific, ADC, CAR-T) against Drug Resistant Breast and Gastric Cancers

Anti-HER2 and Anti-HER3 monoclonal antibodies could be effective against a number of epithelial tumors including HER2-positive metastatic breast cancer, gastric cancer, lung cancer and ovarian cancer

Antibody CDRs against HER2 and HER3 Conformational Domain Bridging Epitopes can be used in multiple formats including bi- and tri-specific antibodies, ADCs (antibody drug conjugates), CAR-T and CAR-NKs, as well as in Quatramers™ and Quatrabodies™

https://finance.yahoo.com/news/hillstream-biopharma-signs-exclusive-option-121100940.html

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