Pzifer Publishes on Phase 3 Data for Zavegepant Spray for Migraine

 

• Zavegepant is the first and only calcitonin gene-related peptide (CGRP) receptor antagonist in development as an intranasal formulation studied in a Phase 3 trial

Pfizer Inc. (NYSE: PFE) today announced publication of results in The Lancet Neurology from the Phase 3 pivotal clinical trial of zavegepant, an investigational calcitonin gene-related peptide (CGRP) receptor antagonist nasal spray for the acute treatment of migraine. The study met its co-primary endpoints, showing that a single 10 mg dose of zavegepant was more effective than placebo for both pain freedom and freedom from the most bothersome symptom (MBS) at two hours post-dose. Additionally, zavegepant demonstrated relief from migraine pain in 15 minutes, with relief lasting up to 48 hours for many patients. Zavegepant was well tolerated, and there were no serious adverse events reported in treated participants.

https://finance.yahoo.com/news/pfizer-announces-lancet-neurology-published-114500177.html