Nektar to Regain Full Rights to Rezpegaldesleukin T-cell (Treg) Therapy in Clinical Stage

 Nektar Therapeutics (Nasdaq: NKTR) today announced that it will be regaining the full rights to REZPEG from Eli Lilly and Company.

As announced in a press release issued on April 17, Nektar plans to move forward with REZPEG and will initiate a Phase 2b study in patients with moderate-to-severe atopic dermatitis in 2023. The company will also explore other auto-immune indications for the development plan for REZPEG.

Phase 1b data for REZPEG in atopic dermatitis were presented at an investment presentation made by Eli Lilly and Company in December 2021 and at the 2022 European Academy of Dermatology (EADV). REZPEG evidenced a dose-dependent improvement over placebo for key efficacy measures of mean change in EASI, EASI-75, vIGA-AD scores, and Itch NRS ≥4-point scales. These improvements were observed for an additional 36 weeks following the 12-week treatment period.

https://www.biospace.com/article/releases/nektar-therapeutics-announces-it-will-regain-full-rights-to-rezpegaldesleukin-rezpeg-nktr-358-a-novel-first-in-class-selective-regulatory-t-cell-treg-therapy-in-clinical-development/