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Monday, September 18, 2023

Kinnate Pipeline Updates, Strategic Reprioritization

 

  • Promising exarafenib combination data in NRAS mutant melanoma; intend to select two doses in the fourth quarter of 2023 for further development

  • Plan to file KIN-8741 c-MET inhibitor Investigational New Drug application and nominate a drug candidate for brain-penetrant CDK4 selective program in the fourth quarter of 2023

  • Completed exarafenib monotherapy dose expansion enrollment and cleared efficacious dose for KIN-3248, FGFR inhibitor; exploring strategic alternatives for both programs

  • Paused KIN-7136 MEK inhibitor development and implementing a workforce restructuring, aligned with reprioritization plan

  • Cash, cash equivalents and investments of $204.3 million as of June 30, 2023, anticipated to fund operations into at least the second quarter of 2026

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