Ozempic as an addiction treatment: 3 notes

 A recent study suggests that semaglutide, typically used for Type 2 diabetes, may significantly reduce the risk of opioid overdoses in patients with opioid use disorder, according to research published Sept. 25 by JAMA Network.

Here are three notes: 

1. The cohort study compared semaglutide's effect on opioid overdose risk against various antidiabetic medications in patients with both Type 2 diabetes and opioid use disorder, using electronic health records from the TriNetX analytics platform. 
   
   
2. Among 33,006 patients, those prescribed semaglutide showed a significantly lower risk of opioid overdose during a one-year followup, with hazard ratios indicating up to 68% reduced risk compared to other antidiabetic drugs. 
   
   
3. The research also indicated that semaglutide may modulate dopamine reward signaling and reduce the craving for drugs such as heroin, showing promise in managing addiction. 

https://www.beckershospitalreview.com/pharmacy/ozempic-as-an-addiction-treatment-3-notes.html