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Saturday, April 26, 2025

Pfizer’s Sasanlimab Combo Improves Event-Free Survival in Bladder Cancer

 

  • Pivotal Phase 3 CREST trial results show a 32% reduction in the risk of disease-related events, including high-grade disease recurrence or progression, with sasanlimab in combination with standard of care (SOC) Bacillus Calmette-Guérin (BCG) regimen compared to SOC alone

  • Sasanlimab, a subcutaneously administered PD-1 inhibitor, in combination with BCG represents the first potential treatment advancement for BCG-naïve, high-risk non-muscle invasive bladder cancer in more than 30 years

  • Results have been shared with global health authorities to support potential regulatory filings

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