Amid demands for retraction, a leading medical journal is reviewing a study published in 2001 that touted the benefits of a depression pill for adolescents, but was subsequently discredited and became the focal point of a searing controversy over inappropriate marketing of the medicine.
The study, which was published in the Journal of the American Academy of Child & Adolescent Psychiatry, made upbeat claims that Paxil was safe and effective for young people. But the underlying data were later found to be misleading because they distorted results, and the study downplayed information that some patients experienced serious side effects, such as suicidal thoughts.
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