The average short interest in the S&P 500 Health Care Index Sector (NYSEARCA:XLV) dipped slightly in July to 1.95% from 1.96% in June. However, Moderna (NASDAQ:MRNA) held its position as the sector's most heavily shorted stock, despite the overall softening of negative sentiment.
The healthcare sector, represented by the Health Care Select Sector SPDR® Fund ETF (NYSEARCA:XLV) and holding a weightage of 12.12% in the S&P 500 index, has slipped 2.62% year-to-date. This underperforms the broader S&P 500 index (SP500), which has risen 9.98% over the same period.
Stocks with the largest and least short positions
Ranked by short interest as a percentage of shares float
Moderna (NASDAQ:MRNA) remained the most heavily shorted stock in the sector, with short interest at 18.29% of its float, a decrease from 19.15% the previous month. Despite the high short position, Seeking Alpha's Quant Rating gives the stock a "Hold" with a score of 2.64 out of 5.
"Moderna (NASDAQ:MRNA) reported a sharp decline in revenue for Q2 2025, earning only $0.1 billion and experiencing a net loss of $0.8 billion. The stock has dropped over 70% in the past year due to investor concerns regarding ongoing losses and reduced demand for COVID vaccines. Despite recent product approval, the company anticipates significant losses in 2025. However, with a strong cash position of $7.5 billion, a revenue recovery is possible through opportunities in vaccines and oncology," a Seeking Alpha analyst wrote.
In July, DaVita (NYSE:DVA) claimed the second spot for highest short interest at 8.99%, just ahead of Henry Schein (NASDAQ:HSIC) at 7.45%.
On the other end, Johnson & Johnson (NYSE:JNJ) had the lowest short interest at 0.71%, followed by Eli Lilly and Company (NYSE:LLY) at 0.85% and AbbVie (NYSE:ABBV) at 0.86%.
Industry Analysis
Average short interest as a percentage of floating shares
In July, biotechnology remained the most heavily shorted industry within the healthcare index for the 16th consecutive month, with short interest ticking up to 2.99% from June's 2.95%. The healthcare provider and services sector also saw a significant increase in short interest, rising to the second-highest level at 2.61%, up from 2.07% in June.
In contrast, the pharmaceuticals' industry stood out with the lowest short interest, which fell to 1.56% for the month.
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