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Friday, June 28, 2024

Walgreens plots bold comeback strategy, but the results will take time

 Walgreens' (WBA) stock is down more than 50% this year as the company continues to face retail headwinds and pivots to a brand new strategy for the pharmacy chain.

CEO Tim Wentworth, who has been on the job for eight months, laid out an aggressive plan to revamp the company on its third quarter earnings call Thursday.

The future Wentworth envisions is one in which pharmacies are local hubs for healthcare access.

The health ecosystem idealizes pharmacies — chains, independents, and online — as a way to maintain patient health. They have also been viewed as expert consultants in the case of minor healthcare needs ranging from advice on over-the-counter products to helping administer specialty drugs on site.

Wentworth wants to double down on that idea by investing in technology to help automate tasks for pharmacists in order to free them up for patients' needs.

"I am confident WBA will be a leader in the future of healthcare, with pharmacy and retail at its center," Wentworth said.

However, that strategy hasn't worked in the past.

The idea of your friendly neighborhood pharmacist clashes with the economics of running a pharmacy and how they get paid by pharmacy benefit managers.

It's the struggle pharmacies of all sizes face with ever-decreasing reimbursements from the three largest pharmacy benefit managers: CVS Caremark (CVS), UnitedHealth's Optum Rx (UNH), and Cigna's Express Scripts (CI), where Wentworth previously served as CEO.

Wentworth said he is fighting "to align incentives and ensure we are paid fairly."

Pharmacies have been fighting since before the pandemic. The impact of consumer trends on front-of-store sales (for beauty and food items), as well as the pressure of being paid fairly for prescriptions, has been the focus of earnings calls for years — and was a catalyst for both Walgreens' and CVS's healthcare services strategy.

COVID offered a brief reprieve for pharmacies, with increased revenues from vaccines, testing, and the need for over-the-counter medications.

That has since tapered off, forcing pharmacies to reduce business hours, close stores, and reconsider how to best utilize storefronts to serve evolving patient needs.

One area in which Walgreens is ahead of the competition is clinical trials.

The company has been converting walk-in clinic spaces into clinical trial spaces and successfully clinched a deal with Boehringer Ingelheim.

The US Food and Drug Administration (FDA) recently announced requirements for drug companies to diversify their clinical trial participant pool, for which Walgreens is now well poised.

But that didn't stop the sell-off Thursday on the news that the company would be struggling in the short term. It lead to the worst day for the company in nearly four decades, closing 22% lower Thursday.

Most analysts believe the company is employing a solid strategy, but it will require patience to execute, especially as a key source of revenue, PBMs, are increasingly becoming competition.

JPMorgan's Lisa Gill said in a note late Thursday that the process would take time.

"We continue to believe that in the longer-term, WBA has the potential for growth. If there is a silver lining to this print, we believe that the company is making the necessary steps to stabilize its footprint and working with PBMs and payors to manage reimbursement headwinds," she wrote.

Bank of America's Allen Lutz similarly noted, "It is imperative that Walgreens pushes back more assertively against PBMs to capture a more reasonable return on capital."

But, he added, "It is not fully clear if a more aggressive push by retail pharmacies would yield favorable results. However, the risk from continuing down the current path for WBA may prove worse."

Walgreens is the largest retail pharmacy chain, with nearly 10,000 locations. Competitor CVS has more than 9,000, and RiteAid — which is currently in bankruptcy even after Walgreens acquired nearly 2,000 locations — has less than 2,000.

https://finance.yahoo.com/news/walgreens-plots-bold-comeback-strategy-but-the-results-will-take-time-181507860.html

J&J Nipocalimab pivotal Phase 3 longest sustained disease control for broadest population in myasthenia gravis

 First-and-only FcRn blocker to demonstrate superiority in activities of daily living (MG-ADLa) over placebo when added to standard of care over 24 weeks in antibody positive patients: anti-AChR+, anti-MuSK+, anti-LRP4+

 Johnson & Johnson (NYSE: JNJ) today announced positive results from the nipocalimab Phase 3 Vivacity-MG3 study in patients with generalized myasthenia gravis (gMG). Patients treated with nipocalimab plus standard of care (SOC) achieved superiority over placebo plus SOC as measured by the primary endpoint of improvement in the MG-ADL score from baseline over 24 weeks. These data are included in a presentation and are among eight abstracts that Johnson & Johnson will present at the European Academy of Neurology (EAN) 2024 Congressand will be included in submissions to regulatory authorities later this year.

https://www.prnewswire.com/news-releases/nipocalimab-pivotal-phase-3-trial-demonstrates-longest-sustained-disease-control-in-fcrn-class-for-broadest-population-of-myasthenia-gravis-patients-302185879.html

Cassava Sciences plunges 40% after simufilam researcher indicted on fraud charges

 Cassava Sciences (NASDAQ:SAVA) has plummeted more than 40% after a Maryland grand jury indicted a company paid consultant and researcher

https://seekingalpha.com/news/4120699-cassava-sciences-plunges-40-after-simufilam-researcher-indicted-fraud-charges

Moscow Threatens Action Against Heightened US Spy Drone Activity

 It has for many months been clear that the world is one incident away from witnessing WW3 in eastern Europe, as NATO gets ever-more deeply involved in Ukraine, and given Moscow has recently issued threats to attack Western airbases housing aircraft which could be deployed in the country.

NATO aircraft, including drones, have also been busier than ever over the Black Sea, just off Russia. Already this has resulted in confrontations like the March 14, 2023 incident in which a Russian Su-27 fighter jet intercepted and damaged an American MQ-9 Reaper drone, causing it to crash in the Black Sea.

This could easily happen again, and the Kremlin on Friday is sounding the alarm over an encroaching US presence over the Black Sea. It is preparing new "rapid response measures" to deal with potential incidents in nearby airspace.

Russian Defense Minister Andrey Belousov has ordered the armed forces to prepare to "react to provocations" due to NATO's increasing involvement in the Ukraine war. The statement was translated and featured in national media reports.

He specifically cited the "increased number of US strategic drone missions flown over the Black Sea" and described that the aircraft "conduct reconnaissance and provide targeting data for weapons, which Western nations supply to conduct strikes on Russian objects."

"Such flights increase the probability that incidents may happen in airspace involving Russian military aircraft and the risk of a direct confrontation of the alliance with the Russian Federation," defense chief Belousov warned additionally.

"NATO members will be held responsible in the event of any such incident," the defense ministry statement added. Possibly Russia could down another NATO drone over the Black Sea in order to send a 'message'.

The warning comes days after the deadly Crimean beach attack which involved Ukraine utilizing its US-supplied ATACMS systems, and also as Kiev is set to receive F-16 fighter jets from European allies.

The jets are expected to be transferred at some point this summer, but already Kiev says it could keep many of them at NATO bases outside Ukraine, such as in Poland or Romania.

President Putin himself has directly warned that any base from which a jet used to attack Russian forces is launched could come under attack, even if it is not in Ukraine.

https://www.zerohedge.com/geopolitical/moscow-threatens-action-more-us-spy-drones-flying-over-black-sea

More Citizens Trust Trump Over Biden To Protect Democracy

 by Jonathan Turley,

The debate last night was chilling for many citizens as President Joe Biden clearly struggled to stay focused and responsive. It appeared to put on display what Special Counsel Robert Hur saw in his interview before concluding that Biden’s loss of mental capacity would make a prosecution difficult.

What may be equally troubling for Democrats and the media is a poll that came out just before the debate that shows more swing-state voters see former President Donald Trump rather than President Joe Biden as protecting democracy.

According to a new poll from the Washington Post and the Schar School of Policy and Government at George Mason University, if “democracy is on the ballot,” the majority of the public believes that threat comes from elsewhere, including possibly Biden himself.

Over half of the respondents told the Washington Post that threats to democracy are extremely important to their vote for president.

However, 44% said they think Trump would do a better job at handling those threats. Only 33% of respondents said they believe Biden would be better for democracy.

Many citizens are alarmed by prosecutions like the one in Manhattan where the legal system seems to have been weaponized against political opponents.

The poll not only shows the diminishing faith in the President but also in the press. The media has been unrelenting in pushing the narrative that this election is a choice between democracy and tyranny. The public is clearly tuning out the media message. This is only the latest example of that widening gap. Indeed, the whole “Let’s Go Brandon” chant is as much a criticism of the media as it is President Biden.

I have previously written that democracy is not on the ballot but free speech is. The Biden Administration has chilling analogies to the Adams Administration in the weaponization of the legal system and the crackdown on free speech. What should most concern Biden is the possibility of another aspect of history repeating itself: a defeat like the one in 1800.

As I discuss in my new book, The Indispensable Right, President John Adams, used the Alien and Sedition Acts to arrest his political opponents – including journalists, members of Congress and others. Many of those prosecuted by the Adams administration were Jeffersonians. In the election of 1800, Thomas Jefferson ran on the issue and defeated Adams.

The anti-free speech movement has flourished largely in the echo chambers of academia and the media.

It is time for the public to render its judgment. Free speech is again on the ballot. It is time for the public to decide.

https://www.zerohedge.com/political/more-citizens-trust-trump-over-biden-protect-democracy

Rite Aid Averts Total Closure, Wins Restructuring Plan Approval

 

  • Restructuring deal hands control of Rite Aid to creditors
  • Pharacy chain closed a quarter of its locations in bankruptcy

Rite Aid Corp. has been cleared to exit bankruptcy after winning court approval on a restructuring plan that’s poised to save the ailing pharmacy chain from liquidation by handing control of the business to key creditors.

Judge Michael Kaplan said Friday he’d approve a restructuring deal that cuts about $2 billion in debt and gives the pharmacy access to about $2.5 billion in exit financing to fund a turnaround plan its advisers have dubbed “Rite Aid 2.0.”

https://www.bloomberg.com/news/articles/2024-06-28/rite-aid-averts-total-closure-wins-restructuring-plan-approval

Biopharma Firm Alumis Shares Fall 20% After Downsized IPO

 

  • Company raised $250 million in IPO, private placement
  • Existing investor AyurMaya bought 2.5 million shares

Shares of Alumis Inc. sank 20% in the clinical stage biopharmaceutical company’s public debut, after it raised $250 million in a downsized initial public offering with a concurrent private placement.

The company’s shares declined on Friday to $12.70 each as of 1:00 p.m. in New York. It sold about 13.1 million shares Thursday, as well as 2.5 million shares in a concurrent private placement to one of its investors, at $16 each.

https://www.bloomberg.com/news/articles/2024-06-28/biopharma-firm-alumis-shares-fall-20-after-downsized-ipo