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Friday, December 14, 2018

HCA on Track for Largest Percent Decrease Since November 2016


HCA Healthcare Inc. (HCA) is currently at $127.75, down $8.57 or 6.29%
— Would be lowest close since Oct. 25, 2018, when it closed at $127.06
— On pace for largest percent decrease since Nov. 9, 2016, when it fell 10.78%
— Snaps a two-day winning streak
— Down 11.28% month-to-date
— Up 45.43% year-to-date; on pace for best year since 2014, when it rose 53.83%
— Up 44.42% from 52 weeks ago (Dec. 15, 2017), when it closed at $88.46
— Third-worst performer in the S&P 500 today

J&J $40B loss in market cap on talc report ‘seems excessive,’ says Wells Fargo


Wells Fargo analyst Lawrence Biegelsen believes Johnson & Johnson shares have been oversold based on today’s Reuters article suggesting that the company knew about asbestos in its baby powder for decades but never told the FDA. He believes any potential settlement should be manageable for J&J, noting that even if all 11,700 talc cases were settled at the highest per case settlement amount among the cases he has tracked, the total liability would be $3.3B. He estimates that the stock has lost over $40B of its market cap so far, which seems excessive based purely on the potential outcomes of the talc litigation. Biegelsen keeps an Outperform rating on Johnson & Johnson shares.
https://thefly.com/landingPageNews.php?id=2837467

Pfizer announces new $10B share repurchase program


The board of directors of Pfizer authorized a new $10B share repurchase program to be utilized over time. This new program is in addition to the $4.9B remaining under the company’s current authorization.
https://thefly.com/landingPageNews.php?id=2837483

Abbott raises quarterly dividend 14% to 32c per share


The board of directors of Abbott increased the company’s quarterly common dividend to 32c per share, marking a 14% increase. The cash dividend is payable Feb. 15, 2019, to shareholders of record at the close of business on Jan. 15, 2019.
https://thefly.com/landingPageNews.php?id=2837451

Tesaro proxy documents point to interest in PARP economics, says Leerink


Leerink analyst Andrew Berens noted that GlaxoSmithKline (GSK) and Tesaro (TSRO) disclosed background details for their deal agreement in a filing this morning. The documents show several parties were interested in a strategic transaction with Tesaro at various points over the last year, though the strategic interest appears to have been driven by Glaxo and one additional company, identified as “Party A”, Berens said. It is not clear why the six other contacted parties were not interested in pursuing a strategic transaction, but he thinks Party A’s co-promote proposal and the initial interest of other potential acquirers indicates strategic interest in the economics surrounding a PARP. Berens, who continues to see Clovis (CLVS) being well-positioned as the remaining stand-alone PARP-focused company, keeps an Outperform rating on Clovis and Market Perform rating on Tesaro.

Clovis drops after Tesaro filing shows interest, but no bids


Shares of Clovis Oncology (CLVS) dropped in morning trading in response to a regulatory filing from Tesaro (TSRO) that showed no other bidders for the company besides GlaxoSmithKline (GSK), which announced a $75 per share offer on December 3.
TESARO FILING: According to a regulatory filing by Tesaro detailing its $75 per share takeover offer from GlaxoSmithKline, Tesaro evaluated a potential co-development collaboration with respect to Zejula, as well as potential financing alternatives available to the company to fund its long-range plan. While several parties were interested in a strategic transaction with Tesaro at various points over the last year, true strategic interest in the company was likely driven by GlaxoSmithKline and one additional company, “Party A,” a large biopharmaceutical company with global expertise in oncology R&D and commercialization. The company’s review of strategic alternatives found that the majority of companies were more interested in buying royalty, licensing or co-development rights instead of pursuing an outright acquisition. On December 3, GlaxoSmithKline said it would buy cancer-focused drug company Tesaro for about $4.16B. In acquiring Zejula, Tesaro’s ovarian cancer drug, GlaxoSmithKline will compete with AstraZeneca’s (AZN) market-leading Lynparza, as well as a poly ADP ribose polymerase, or PARP, inhibitor from Clovis Oncology. Zejula’s sales have lagged behind rivals, with doctors and industry officials saying the treatment’s side-effect profile is worse than the other drugs. Tesaro unsuccessfully explored a potential sale more than a year ago, with four companies — not including Glaxo — executing non-disclosure agreements and performing due diligence, but ultimately failing to reach an agreement.
ANALYST COMMENTARY: Gabelli analyst Je Hing recently highlighted Clovis as a likely takeout target, telling investors earlier this week in a research note that with the Tesaro  acquisition by GlaxoSmithKline, Clovis will become the only standalone PARP. He named Bristol-Myers (BMY), Sanofi (SNY) and Roche (RHHBY) as the most interested buyers. Leerink analyst Andrew Berens said on Friday that he sees “Party A’s” interest, including the final offer of $2.34B including upfront and contingent payments for a 50/50 profit split, as validating for interest in the PARP class and valuation. He thinks Clovis shares might see some weakness today, as investors may have been hopeful that the filing would have included additional interested parties or acquisition offers for Tesaro, suggesting a competitive process. The analyst said investors may interpret the lack of additional takeover offers in the home stretch as suggesting there is no buyer for Clovis, but caution that Clovis would likely receive different types of suitors than Tesaro because of differences in the the companies’ profiles.

Leap TRX518 Data and call at ESMO Immuno-Oncology Congress 2018


Leap Therapeutics Inc. (NASDAQ:LPTX) today presented clinical data from its ongoing Phase I/II study of TRX518 in combination with gemcitabine, KeytrudaÒ (pembrolizumab), or OpdivoÒ (nivolumab) in patients with advanced solid tumors at the European Society for Molecular Oncology (ESMO) Immuno-Oncology Congress 2018.  In addition, Leap provided the top-line final data from the Phase I/II study of DKN-01 in combination with gemcitabine and cisplatin chemotherapy in patients with advanced biliary tract cancer.
Leap will host a conference call and webcast on Monday, December 17, 2018 at 8:30 AM US Eastern Time with Jason J. Luke, MD, Assistant Professor of Medicine, Pritzker School of Medicine at the University of Chicago and Todd M. Bauer, MD, Sarah Cannon Research Institute/Tennessee Oncology PLLC, TN.  Drs. Luke and Bauer will discuss patient outcomes and provide additional perspectives about the TRX518 program.
On Monday, December 17, 2018 at 8:30AM ET, Leap will be hosting a conference call and webcast for the investment community. To access the conference call, please dial (866) 589-0108 (US/Canada Toll-Free) or (409) 231-2048 (international) and refer to conference ID 9187987. The presentation will also be webcast live and will be available on Leap’s website, https://www.leaptx.com/program-webcastshttps://edge.media-server.com/m6/p/28e7k6ei. A replay of the webcast will be available on Leap’s website after the event and will be available for a limited time.