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Wednesday, November 6, 2019

Humana EPS beats by $0.47, beats on revenue

Humana (NYSE:HUM): Q3 Non-GAAP EPS of $5.03 beats by $0.47; GAAP EPS of $5.14 beats by $0.67.
Revenue of $16.24B (+14.3% Y/Y) beats by $90M.

Voyager Therapeutics EPS beats by $0.32, beats on revenue

Voyager Therapeutics (NASDAQ:VYGR): Q3 GAAP EPS of -$0.41 beats by $0.32.
Revenue of $20.43M (+877.5% Y/Y) beats by $13.84M.
Shares +1.95% PM.

CVS Health EPS beats by $0.07, beats on revenue

CVS Health (NYSE:CVS): Q3 Non-GAAP EPS of $1.84 beats by $0.07; GAAP EPS of $1.17 misses by $0.08.
Revenue of $64.8B (+36.4% Y/Y) beats by $1.81B.
Shares +0.1% PM.

AstraZeneca to distribute Sun Pharma cancer drugs in China

Indian drugmaker Sun Pharmaceutical Industries Ltd said on Wednesday Britain’s AstraZeneca would distribute some of Sun’s cancer treatment drugs in China, the world’s second-largest pharmaceutical market.

Shares of the Mumbai-based company rose as much as 5.4% to a nine-week high after the announcement.
As per the licensing agreement, Sun will be responsible for development, regulatory filings and manufacturing of the drugs, while AstraZeneca will exclusively promote and distribute the products in China, according to a filing https://www.bseindia.com/xml-data/corpfiling/AttachLive/e10d3bee-3ab1-4a0f-ab45-600f16796260.pdf to Indian stock exchanges.
The company did not name the drugs covered under the agreement, which comes after Chinese President Xi Jinping last month welcomed Indian investment in pharmaceuticals https://in.reuters.com/article/uk-india-china-summit/india-china-agree-to-tackle-trade-deficit-at-modi-xi-summit-idINKBN1WR078 and textiles.
Cancer has been on the rise in China, driven by air pollution and high rates of smoking. Water pollution and excessive use of chemical fertilisers and pesticides have also been blamed for an increase in cancer rates in rural areas.
“We see a great potential to introduce our speciality and generic products in the growing China market,” said Kal Sundaram, Sun Pharma’s director of corporate development.
Financial terms of the agreement, which has an initial tenure of 10 years, were not disclosed.

AstraZeneca launches $1B China investment fund

Making a big bet on the world’s second-largest pharma market, AstraZeneca (NYSE:AZN) aims to raise up to $1B for a new fund that would invest in Chinese healthcare startups.
The fund – a joint venture between AstraZeneca and China International Capital Corporation – has drawn interest from investors such as Sequoia Capital.
It aims to raise between $200M to $300M this year, and as much as $1B over four years.

Perrigo EPS beats by $0.10, misses on revenue

Perrigo (NYSE:PRGO): Q3 Non-GAAP EPS of $1.04 beats by $0.10; GAAP EPS of $0.67 beats by $0.09.
Revenue of $1.19B (+5.3% Y/Y) misses by $10M.
Shares +0.4% PM.

Tuesday, November 5, 2019

Social media, not docs, increasingly diagnosing STDs

The HIV test came back positive and the patient, full of fear and denial, took to the STD forum on the popular social media site Reddit.
“I’m really scared because they said my results showed ‘HIV-1 Confirmation.’ I have to go back and get another test but I’m wondering is the doc wrong, do you think I have HIV?” the person wrote.
People worried that they have a sexually transmitted disease are more often turning to social  to receive a diagnosis, according to a report published Nov. 5 in the Journal of the American Medical Association.
Nearly 3 of every 5 posts to Reddit’s STD forum is seeking a “crowd diagnosis” of a suspected infection, often with an accompanying photo of affected genitalia, said senior researcher John Ayers. He’s an associate professor with the Division of Infectious Disease and Global Public Health at the University of California, San Diego.
Worse, 20% of people requesting an STD crowd diagnosis through Reddit specifically sought a  after receiving a diagnosis by a  professional.
“One in 5 people that went on here was already told by a doctor what their condition was,” Ayers said. “They go on social media to refute that diagnosis.”
He said the phenomenon is disturbing, and not just because it takes the dreaded office question, “Does this look normal?” to a global scale.
There’s a good chance that people are being given misleading or wrong information, which increases the risk of spreading the infection to others, Ayers said.
“We’re undergoing an STD epidemic right now, and in part that epidemic may be fueled by people’s reliance on social media for health care,” he said.
Ayers cited the frightened HIV-positive patient as an example. That post received a reply within an hour, researchers found.
“They go online and they get told they don’t have HIV, which means that person is going to go now and infect more people,” Ayers said.
Rising rates of STDs
The rates of new HIV diagnoses in the United States have remained stable in recent years, according to the U.S. Centers for Disease Control and Prevention, but infection rates for other STDs are skyrocketing:
  • Chlamydia infections are up 19% since 2014, and now stand at 1.8 million.
  • There’s been a 63% increase in gonorrhea cases during that time, to more than 583,400.
  • Primary and secondary syphilis are up 71%, with more than 35,000 cases.
  • Congenital syphilis passed from mother to baby has increased 185%, with more than 1,300 cases.
Ayers and his colleagues noted that people are increasingly turning to social media for information about STDs and other illnesses.
“Remote care” and “telemedicine” are concepts that have been kicking around for some time, but doctors may be surprised by the extent to which people already are participating, Ayers said.
“People are already doing remote care. They’re just doing it in the wrong setting. They’re doing it on social media,” he said.
To gain some understanding, the researchers focused on Reddit, a social media website with 330 million active monthly users. The site hosts more than 232 health forums, also called “subreddits,” including one focused on STDs.
“None of them are dedicated to diagnosis,” Ayers said. “They’re all about sharing information and social support. But the reality is they all turn into a forum for crowd diagnoses.”
Ayers and his team gathered posts on Reddit’s STD forum from its start in November 2010 through February 2019, nearly 17,000 in all.
The monthly number of posts have been steadily increasing over the years, with 908 appearing in January and February 2019.
Researchers drew a random sample of 500 posts to see how many were seeking crowd diagnoses.
About 58% of posts requested a crowd diagnosis. Nearly one-third of those requests included a photo of the person’s physical symptoms, “which basically meant they were sexting, for want of a better word,” Ayers said.
One example involved a person who posted a photo and asked: “Is this ingrown hairs or genital warts?”
“I went to the doc a few days ago and he said it’s genital wart,” the post continued. “I’m floored because I always use condoms. I recently shaved so the doctor could be wrong and they’re ingrown hairs? Here’s a pic. I’d appreciate a second opinion. If it is warts, I may try apple cider vinegar first.”
Nearly 9 out of 10 requests for a crowd diagnosis received a reply, and many received multiple replies, Ayers said. Some posts received a reply in less than a minute.
“Crowd diagnoses are becoming popular because strangers are so willing to try to help,” Ayers said.
He noted that 79% of requests were answered in less than a day. “Try getting a doctor’s opinion in that time,” Ayers said.
Can health care take advantage of social media?
Dr. Stacey Rizza is an infectious disease expert at the Mayo Clinic in Rochester, Minn., who reviewed the findings. She said she’s alarmed that people are turning to social media rather than doctors to deal with their STDs.
“In my opinion, I don’t think that’s the appropriate way to diagnose anything,” Rizza said. “But in infectious diseases, it’s not just that one person. Other people will be impacted, too.”
While it is concerning, Dr. Amesh Adalja sees opportunity in the trend, as well.
“This phenomenon should be seen as an opportunity for health care providers to engage with patients on social media to ensure accurate diagnosis and advice is being given,” said Adalja, a senior scholar at the Johns Hopkins Center on Health Security in Baltimore who also reviewed the study. “Exploiting the ease of social media inquiry will likely become an increasingly important way to interact with patients.”
Ayers agreed. He said public health officials and organizations should partner with  platforms to improve the information being shared and make sure people are turning to their doctor for a proper .
He noted that Reddit’s forum on suicide is staffed by volunteers who encourage people to seek qualified help.
“If that existed for the STD forums, maybe we could get more people to engage with the professional help they need and actually get better,” Ayers said.

Explore further

More information: The U.S. Centers for Disease Control and Prevention has more about sexually transmitted diseases.Alicia L. Nobles et al. Requests for Diagnoses of Sexually Transmitted Diseases on a Social Media Platform, JAMA (2019). DOI: 10.1001/jama.2019.14390