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Tuesday, January 24, 2023

bioAffinity: Noninvasive Test Developed Using Machine Learning Detects Early-Stage Lung Cancer

 -bioAffinity Technologies, Inc. (NASDAQ: BIAF; BIAFW) today announced publication of "Detection of early-stage lung cancer in sputum using automated flow cytometry and machine learning" detailing results of the Company’s clinical trial for its non-invasive diagnostic CyPath® Lung in Respiratory Research, one of the leading peer-reviewed open access journals in the field of respiratory medicine.

CyPath® Lung showed 92% sensitivity and 87% specificity in high-risk patients who had nodules smaller than 20 millimeters or no nodules in the lung, with an area under the ROC curve of 94%. Overall, the test resulted in specificity of 88% and sensitivity of 82%, similar to far more invasive procedures currently used to diagnose lung cancer. More than half of those in the cancer cohort had early Stage I or II lung cancer. CyPath® Lung detected multiple forms of cancer including adenocarcinoma, squamous cell carcinoma and small cell lung cancer.

https://finance.yahoo.com/news/bioaffinity-technologies-announces-publication-results-130000525.html

Sandoz announces agreement to acquire leading antifungal agent Mycamine® from Astellas

 

  • Sandoz plans to acquire worldwide product rights for Mycamine® (micafungin sodium) from Astellas

  • Acquiring leading global echinocandin, one of three major antifungal classes, will significantly reinforce Sandoz hospital offering and leading anti-infectives portfolio

  • Addition of Mycamine® will support Sandoz global program to combat antimicrobial resistance (AMR) by targeted use of most appropriate therapies

J&J eyes 3.5% EPS growth in 2023

 

  • 2022 Fourth-Quarter reported sales decline of 4.4% to $23.7 Billion primarily driven by unfavorable foreign exchange and reduced COVID-19 Vaccine sales vs. prior year. Operational growth excluding COVID-19 Vaccine of 4.6%*

  • 2022 Fourth-Quarter earnings per share (EPS) of $1.33 decreasing 24.9% and adjusted EPS of $2.35 increasing by 10.3%*

  • 2022 Full-Year reported sales growth of 1.3% to $94.9 Billion primarily driven by strong commercial execution partially offset by unfavorable foreign exchange. Operational growth of 6.1%*

  • 2022 Full-Year earnings per share (EPS) of $6.73 decreasing 13.8% and adjusted EPS of $10.15 increasing by 3.6%*

  • Company guides 2023 adjusted operational sales growth excluding COVID-19 Vaccine of 4.0%* and adjusted operational EPS of $10.50, reflecting growth of 3.5%*

Monday, January 23, 2023

NYC scraps plan to place 3 Success Academy charters in city schools

 New York City Schools Chancellor David Banks said Monday that the city will scrap proposals that would have co-located three Success Academy schools in public school buildings.

Banks said the Department of Education nixed the idea to place two new charter schools in Queens and one new charter school in the Bronx after receiving backlash from the community.

The city’s top school official said the decision was made after community members complained that the proposals “would create significant challenges for the new schools and the existing co-located schools.”

Banks’ statement comes a day before the Panel for Educational Policy was scheduled to vote on the two Queens schools, according to NY1.

One of the proposals would’ve placed a Success Academy elementary school at the Catherine and Count Basie Middle School 72 building, which has two middle and special education campuses in Rochdale Village.

The other Queens charter elementary school would’ve been placed at the Springfield Gardens Education Campus, which houses multiple high schools.

The failed proposal that would’ve placed a Success Academy elementary school at a Bronx school building was supposed to be discussed Wednesday, NY1 reported.  

New York City Schools Chancellor David Banks announced a plan to co-locate three Success Academy charter schools in public school buildings has been canceled.
New York City Schools Chancellor David Banks announced a plan to co-locate three Success Academy charter schools in public school buildings has been canceled.
Stephen Yang

Co-locating of the trio of charter schools was fiercely opposed by the United Federation of Teachers.

Some parents and faculty also voiced opposition to the plan with the two sides arguing over whether the space is actually there to house more students.

“We can’t force additional students into a building where there’s no space and then condemn New York City schools for failing,” said Adriana Alicea, president of District 28’s President’s Council of one of the Queens proposals, according to Chalkbeat New York. “There’s no space for the children to succeed. There’s no space for them to grow.”

Success Academy did not immediately return an email and phone call Monday night.

One of the Success Academy schools was supposed to be in he Catherine and Count Basie Middle School 72 building in Queens.
One of the Success Academy schools was supposed to be in the Catherine and Count Basie Middle School 72 building in Queens.
Helayne Seidman
Success Academy Founder and CEO Eva Moskowitz previously shot down concerns about space at the proposed co-location schools.
Success Academy Founder and CEO Eva Moskowitz previously shot down concerns about space at the proposed co-location schools.
Christopher Goodney/Bloomberg via Getty Images

But a spokesperson for the charter school system, Ann Powell, previously told Chalkbeat, “Our schools are tremendously popular in Queens.” Powell also said that 500 families in part of the Bronx need to “commute significant distances to attend other Success Academies.

Success Academy Founder and CEO Eva Moskowitz previously told NY1 concerns over space in the buildings were nothing more than scare tactics.

“Co-location is just such an important public policy,” Moskowitz reportedly said. “This is about of course Success, but it’s also about the policy. Do we really want a city where you leave 40% of the seats empty? They were expensive to build, those buildings.”

Charter schools are legally allowed to vacant space in Department of Education buildings and have done so for years.  

Banks, in his Monday statement, vowed to work with Success Academies “to find suitable facilities for their new schools.”

https://nypost.com/2023/01/23/nyc-scraps-plan-to-place-3-success-academy-charters-in-city-schools/

SCOTUS Failure To Identify Dobbs Leaker "Chilling", Turley Warns "Danger Will Only Grow"

 by Samantha Flom via The Epoch Times,

George Washington University law professor Jonathan Turley criticized the Supreme Court on Jan. 19 over its failure to determine who leaked a draft of the court’s Dobbs v. Jackson Women’s Health Organization opinion.

After a months-long investigation sparked by the May leak, the court released its much-anticipated investigative report (pdf) on the matter Thursday, finding that it was “not possible” to identify the person responsible for the breach or how the document had ended up in the hands of Politico.

“The Supreme Court’s report indicates that they cannot isolate the culprit among the over 80 possible suspects for the Dobbs leak,” Turley noted in a series of Jan. 19 tweets.

“It is an admission that is almost as chilling as the leak itself.”

Turley also posited that, despite the security recommendations of the court’s marshal, the inconclusive investigation would likely only serve to embolden future leakers.

“The nature of the Court’s work requires a free flow of drafts and memoranda,” he noted. “That is why we hope to achieve through deterrence what was not achieved through ethics.

“In this age of rage, this danger will only grow,” he added.

“Someone felt that they had license to leak. Some others may now feel that they have the impunity to do so.”

The Leak

While, in general, Supreme Court leaks are rare, the Dobbs leak was made all the more significant by the implications of the ruling on nearly a half-century of abortion law in the United States.

Politico, having exclusively obtained an early draft of the opinion, published it May 2 as part of a report titled, “Supreme Court has voted to overturn abortion rights, draft opinion shows.”

Although the draft differed slightly from the final opinion the court would issue on June 24, the decision was the same: The court ruled 5–4 that there is no constitutional right to abortion, striking down the precedents set by the 1973 landmark abortion case of Roe v. Wade and the subsequent 1992 ruling in Planned Parenthood v. Casey.

The leaked draft sparked national protests, including outside the homes of conservative justices, with Justice Brett Kavanaugh becoming the target of an assassination attempt.

Calling the leak an “egregious breach” of the court’s trust, Chief Justice John Roberts ordered an investigation into its source.

“To the extent this betrayal of the confidences of the Court was intended to undermine the integrity of our operations, it will not succeed,” Roberts assured in a May 3 statement.

“The work of the Court will not be affected in any way.”

The Investigation

Prior to Thursday’s report, the court had been tight-lipped on the progress of its investigation, with the only updates coming from anonymous sources.

Led by Supreme Court Marshal Gail Curley, the court’s investigative team comprised “seasoned attorneys and trained federal investigators with substantial experience conducting criminal, administrative and cyber investigations,” per Curley’s report.

But after conducting 126 formal interviews of 97 employees, the team was unable to identify the individual responsible for the leak.

“No one confessed to publicly disclosing the document and none of the available forensic and other evidence provided a basis for identifying any individual as the source of the document,” Curley noted.

While the possibility of a hack could not be entirely ruled out, the team found that the evidence did not suggest improper outside access.

Investigators were likewise unable to rule out inadvertent or negligent disclosure, “for example, by being left in a public space either inside or outside the building.”

Additionally, despite reports that the justices were not interviewed as part of the investigation, Curley clarified in a statement Friday that she did speak with them in addition to their staff.

“During the course of the investigation, I spoke with each of the Justices, several on multiple occasions,” she said. “The Justices actively cooperated in this iterative process, asking questions and answering mine. I followed up on all credible leads, none of which implicated the Justices or their spouses. On this basis, I did not believe that it was necessary to ask the Justices to sign sworn affidavits.”

While also noting in her report that investigators were still reviewing and processing some electronic data and that a few inquiries were pending, Curley proposed several security improvements to prevent future breaches, including enhanced training, tracking mechanisms to monitor the printing and copying of documents, and policy updates on the handling of draft opinions and who can access sensitive information.

In a statement attached to the report, the court offered Curley their “full support” as she and her team continue their investigation.

https://www.zerohedge.com/political/supreme-courts-failure-identify-dobbs-leaker-chilling-jonathan-turley-warns-danger-will

Australians Were Once Prosecuted For Claiming Face Masks Worked Against Viruses

 by Paul Joseph Watson via Summit News,

Australians who tried to sell surgical face masks on the back of claims they worked against viruses were once threatened with prosecution and massive fines by the government.

An article titled ‘Farce mask: it’s safe for only 20 minutes’ published by the Sydney Morning Herald in 2003 explained how, “Retailers who cash in on community fears about SARS by exaggerating the health benefits of surgical masks could face fines of up to $110,000.”

The article quotes a public health experts who said that face masks are largely useless at stopping the spread of viruses and could even worsen the situation.

“Those masks are only effective so long as they are dry,” said Professor Yvonne Cossart of the Department of Infectious Diseases at the University of Sydney.

“As soon as they become saturated with the moisture in your breath they stop doing their job and pass on the droplets.”

Professor Cossart said that the masks would need to be changed every 15-20 minutes to be in any way effective.

Her sentiments were echoed by John Bell from the Pharmaceutical Society of Australia, who said that masks only offered “marginal benefit” and were largely psychological in their level of protection.

The story is noteworthy because during the COVID pandemic, the Australian government imposed one of the strictest lockdowns in the world and used face mask mandates as a brutal tool of population control.

As we previously highlighted, authorities in Melbourne used high-tech surveillance drones to catch people outside not wearing masks.

At the height of the hysteria, there were numerous instances of police in Australia physically attacking people for not adhering to mask wearing rules, including one incident when a woman was placed in a chokehold by a male police officer.

Another video showed an elderly woman being arrested for not wearing a mask while sitting on a park bench.

Yet another clip showed police pepper spraying pre-teen children for not wearing face masks.

Another clip showed an elderly man suffering a suspected heart attack after he was arrested by police for not wearing a mask outside while exercising.

During the early months of the COVID pandemic, health authorities advised against wearing masks, only to subsequently do a 180 once face coverings became a convenient psychological tool of population control.

https://www.zerohedge.com/covid-19/australians-were-once-prosecuted-claiming-face-masks-worked-against-viruses

As teen violence surges, Hochul fails to address a key cause: NY’s disastrous Raise the Age law

 Teen violence continues to spiral out of control, yet Gov. Kathy Hochul refuses to lift a finger when it comes to one of its key drivers: the 2017 Raise the Age law, which prevents anyone under 18 from being prosecuted as an adult.

Before Raise the Age, 16- and 17-year-olds could be charged as adults; now such suspects are likely to be sent to Family Court, where they barely face consequences.

Yet New York is facing an ugly surge of teen violence, including terrifying shootings at city schools. Last week, a 13-year-old was charged with opening fire and wounding two other teens at Campus Magnet HS in Queens.

Gangs, as Mayor Eric Adams (an ex-cop) has pointed out, often make younger members their gunmen, knowing they’ll get off easy if caught — a practice Raise the Age encourages.

And the fallout is already clear: Nearly one out of five perps nabbed for robbery last year was under 18, as NYPD brass fumed this month. Over the past three years, the number of under-18 shooters more than doubled, from 48 in 2019 (when Raise the Age took full effect) to 124 last year. The number of teens struck by gunfire mushroomed at a similar rate, from 64 to 153.

And the future looks even worse, with more kids returning to crime after cushy collars. “Nearly half of 16-year-olds arrested in the first year of Raise the Age were rearrested within 15 months,” including a quarter for violent felonies, former Bronx ADA W. Dyer Halpern warned in City Journal last year. The numbers “significantly outpace similar arrests” a year before Raise the Age, as does “the recidivism rate for 17-year-olds arrested over the same period.”

Gov. Kathy Hochul has refused to address the 2017 Raise the Age Law despite the surge in teen violence in New York City.
Gov. Kathy Hochul has refused to address the 2017 Raise the Age Law despite the surge in teen violence in New York City.
Kevin C. Downs for NY Post

Hochul talks plenty about gun laws, but ignores Raise the Age: She failed to mention it in her State of the State or in her 277-page program book. It seems the gov’s only too happy to let kids run around with guns in their hands, wreaking havoc on everyone (including themselves).

“We can’t normalize this. We can’t continue to ignore the violence that is really engulfing our young people,” pleads Adams. “If we don’t intervene, they are on a pathway of a career in violence, and we have to stop it.”

He’s dead right. Question is: Can he get Hochul and the hard-hearted leftist ideologues in the Legislature to listen?

https://nypost.com/2023/01/23/as-teen-violence-surges-hochul-fails-to-address-a-key-cause-nys-disastrous-raise-the-age-law/