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Tuesday, April 7, 2026

Iran’s president says Guards commanders are wrecking ceasefire chances

 A deepening rift at the top of the Islamic Republic has spilled into an unusually sharp confrontation, with President Masoud Pezeshkian accusing senior Guards commanders of unilateral actions that have wrecked ceasefire prospects and pushed Iran toward disaster.

Two sources close to the presidential office said a tense exchange took place on Saturday, April 4, between Pezeshkian and Hossein Taeb, a powerful figure close to Supreme Leader Mojtaba Khamenei. Those present described the conversation as unusually difficult and highly charged.

During the meeting, Pezeshkian accused IRGC chief commander Ahmad Vahidi and Ali Abdollahi, commander of Khatam al-Anbiya Central Headquarters – the country’s armed forces' unified command, of acting unilaterally and driving escalation through attacks on regional countries, especially against their infrastructure.

According to the sources, Pezeshkian said those policies had destroyed any remaining chance of a ceasefire and were steering the Islamic Republic directly toward “a huge catastrophe.”

He also warned that, based on what he described as precise assessments, Iran’s economy would not be able to withstand a prolonged war for much longer and that full economic collapse was inevitable under current conditions.

The confrontation comes amid mounting evidence of a broader power shift inside the Islamic Republic, with military and intelligence networks increasingly displacing both the elected government and the traditional clerical order.

Ideological collapse and hidden state

A regional source familiar with internal developments told Iran International in February that the model of velayat-e faqih (guardianship of the jurist) that has defined the Islamic Republic for more than four decades is now undergoing a fundamental transformation and even an “ideological collapse.”

According to that source, the appointment of Mojtaba Khamenei to the leadership, despite lacking the traditional qualifications and legitimacy associated with the position, took place through an opaque process that in practice amounts to the sidelining of the traditional clergy and the consolidation of full control by the Guards’ military-intelligence apparatus.

The source said this process has strengthened what many insiders describe as the Islamic Republic’s “hidden state.”

Iran International has previously reported growing tensions between Pezeshkian and senior IRGC commanders, particularly Vahidi, over how the war should be managed and over its destructive impact on people’s livelihoods and the economy.

On March 28, informed sources said Pezeshkian had criticized the Guards’ approach to escalating tensions and continuing attacks on neighboring countries, warning that without a ceasefire the economy could collapse within three weeks to a month.

Subsequent reporting by Iran International showed that the president’s authority has continued to shrink.

Sources said the Guards have resisted Pezeshkian’s appointments and decisions, effectively stripped the government of executive control and erected a security barrier around the core of power.

According to those reports, Pezeshkian’s attempt to appoint a new intelligence minister collapsed under direct pressure from Vahidi, who rejected all proposed candidates, including Hossein Dehghan, and insisted that all key wartime positions must, for now, be chosen and managed directly by the Guards.

Iran International also reported that Pezeshkian was forced, under direct IRGC pressure, to appoint Mohammad Bagher Zolghadr as secretary of the Supreme National Security Council

despite his dissatisfaction with the choice.

Logistical crisis

Alongside the political infighting, fresh field reports received by Iran International point to a worsening human and logistical crisis inside the Guards and the Basij.

Sources said that over the past 72 hours, operational forces have faced acute shortages of basic supplies, including edible food, hygiene facilities and places to sleep.

Recent strikes on infrastructure and bases have left many Guards and Basij personnel sleeping in the streets, and in some areas they have had access to only one meal a day.

According to informed sources, some personnel were forced to buy food from shops and restaurants with their own money after expired rations were distributed.

At the same time, disruptions affecting Bank Sepah’s electronic systems have reportedly delayed the salaries and benefits of military personnel, fueling fresh anger and mistrust within the ranks.

Iran International had previously reported similarly dire conditions in field units, including severe shortages of ammunition, water and food, as well as growing desertions by exhausted soldiers.

Even in the Guards’ missile units, which have historically received priority treatment, sources reported serious communications failures and food shortages. They said commanders were continuing to send only technical components needed to keep missile systems operational, rather than food or basic individual supplies for personnel.

https://www.iranintl.com/en/202604074692

AWS 'working 24/7' to keep Middle East services up

 Amazon Web Services (AWS) CEO Matt Garman told CNBC on Tuesday that the company's teams are "working 24/7" to keep the services running in the Middle East amid the raging war in Iran.

"It’s a really difficult situation, and we’re working incredibly hard," Garman told the outlet at the HumanX conference in San Francisco. Commenting on the economic implications of the war, he assessed that it is "obviously hugely disruptive for the global economy," but that "there's a willingness to invest ... and so our and my excitement about investing long term in that region is just as strong as it’s ever been."

Many AWS services in Bahrain and the United Arab Emirates remain unavailable according to the company's status page.

https://breakingthenews.net/Article/AWS-'working-247'-to-keep-Middle-East-services-up/66023876

'Politico: Israel said to push for longer campaign against Iran'

 The Israeli authorities are supposedly in favor of a longer campaign against Tehran in order to weaken the Iranian regime further amid United States President Donald Trump's deadline, Politico reported on Tuesday.

The media outlet cited sources familiar with the matter, who shared that Israel believes that it is "premature" for a ceasefire and that military operations against Iran could continue for "at least another month."

According to the sources, Israel aims to weaken the Iranian regime sufficiently to pave the way for its eventual collapse.

https://breakingthenews.net/Article/Israel-said-to-push-for-longer-campaign-against-Iran/66024236

New round of Iranian strikes target Gulf countries

 Iran launched another wave of attacks against Bahrain, the United Arab Emirates, and Qatar on Tuesday, as the conflict in the region escalated further.

The media said blasts were heard in Qatar's capital, Doha, while air defenses were activated in the skies of the UAE and Bahrain. Iranian news outlets reported that powerful explosions occurred in all three nations. There have been no immediate reports of damage or casualties. Earlier today, Kuwait warned its citizens to remain in their homes starting from midnight until 6 am on Wednesday local time.

https://breakingthenews.net/Article/New-round-of-Iranian-strikes-target-Gulf-countries/66024269

Trump says US in 'heated negotiations' with Iran

 United States President Donald Trump told Fox News on Tuesday that he cannot comment on Pakistan's proposal for a two-week extension of his deadline to Iran, adding that the US is currently engaged in "heated negotiations" with Tehran.

The US leader added he would soon receive a full briefing on the proposal.

https://breakingthenews.net/Article/Trump-says-US-in-'heated-negotiations'-with-Iran/66024399

Aramco eyed as target if US hits Iran power plants

 Saudi Aramco's oil facilities could become Iran's next target, should the United States start striking the country's power plants, Tasnim News reported on Tuesday, citing a military source.

"We have prepared some nice surprises for [US President Donald] Trump’s possible madness," the official was quoted as saying, adding that Yanbu and Fujairah oil facilities are also possible targets. "In the event of Trump’s crime, Iran will not hesitate to impose heavy costs on the United States and its partners," he noted.

The source added that Trump can expect oil prices to reach $200 per barrel in the coming days if he delivers on his earlier threats.

https://breakingthenews.net/Article/Aramco-eyed-as-target-if-US-hits-Iran-power-plants/66024138

FDA Seeks Expanded Authority To Regulate Postapproval Manufacturing Changes

 

Aiming to protect patients, the FDA sent lawmakers a wish list of legislative proposals intended to clarify and expand its oversight of updates to approved drug production processes.

The FDA is seeking new powers to enforce requirements related to postapproval manufacturing changes as part of the Trump administration’s fiscal year 2027 budget proposal.

Through the funding request, released April 3, the agency proposed legislative changes intended to help it meet its goals for 2027. One proposal covers the validation and authorization of postapproval manufacturing updates. These include major changes such as the use of a different facility or active pharmaceutical ingredient (API) supplier. Such changes can adversely affect the safety or effectiveness of the finished product.

To mitigate that risk, the FDA has proposed revising drug and biologics laws to clarify the agency’s ability to enforce manufacturing change requirements. The legislative changes are intended to ensure that people are not exposed to medicines until postapproval changes have been appropriately validated.

Legislation published in 1997 requires manufacturers to receive approval for major changes, which the FDA will review before they apply to products delivered to patients. However, the agency has identified a need to revise various sections of the Federal Food, Drug, and Cosmetic Act and Public Health Service Act to clarify its powers.

The FDA has also requested “express authority to require actions to address residual quality risks in the postapproval period.” Using its authority, the agency could make companies provide information on ongoing quality via postapproval updates.

The FDA said the powers would support its ability to identify and act against adulterated products.

The agency also wants lawmakers to confirm and expand its ability to disclose and use certain information related to drug impurities when it deems these actions to be in the interest of public health. The FDA said early identification of impurities and disclosure of acceptable intake limits would support timely corrective actions, such as changes to manufacturing processes and product reformulations.

Other proposals include a request for powers to withdraw products from the market if companies fail to report how much API they source from each supplier listed in their approval submissions. The FDA said the current situation hinders its visibility into the supply chain.

The proposals will facilitate the FDA’s transition “from a reactionary system to a proactive system,” Commissioner Marty Makary wrote in his opening letter for the 2027 budget document.

Finally, the budget proposal includes a request for $9 million and 19 full-time employees to accelerate advanced manufacturing. The money will fund initiatives including PreCheck, a new FDA program intended to help companies build manufacturing facilities in the U.S.

https://www.biospace.com/fda/fda-seeks-expanded-authority-to-regulate-postapproval-manufacturing-changes