Cantor Fitzgerald analyst Eliana Merle views the first clinical data of an IL36R inhibitor in patients presented at EADV Congress as a positive read-through to AnaptysBio’s IL36R program. Anaptys’s second wholly owned clinical stage asset, ANB019, is an IL36R inhibitor in development for rare forms of psoriasis, Merle tells investors in a research note. She points out that data over the weekend from a competitor program, BI 655130, showed that IL36R inhibition can lead to clinically meaningful improvement in generalized pustular psoriasis. The analyst thinks this de-risks the IL36R mechanism ahead of initial patient data from ANB019 in GPP in early 2019. Merle keeps an Overweight rating on AnaptysBio with a $124 price target
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