Mission-AbbVie Alzheimer’s, Parkinson’s Collaboration Reaches Milestone

Mission Therapeutics (“Mission”), a drug discovery and development company focused on selectively inhibiting deubiquitylating enzymes (DUBs), and AbbVie (“AbbVie”)(NYSE: ABBV), a global, research-driven biopharmaceutical company, today announced the identification of several DUBs as potential drug targets in their Alzheimer’s and Parkinson’s R&D collaboration.

AbbVie has nominated the panel of DUBs that will be progressed for further characterization and screening activities. This is the first major milestone of the Companies’ DUB research and preclinical development collaboration in neurodegenerative diseases.

Under the terms of the collaboration, announced in November 2018, Mission and AbbVie are working together to identify specific DUBs and discover suitable inhibitor compounds for the treatment of Alzheimer’s and Parkinson’s diseases. AbbVie then has the option to gain exclusive rights to develop and commercialize DUB inhibitors against up to four selected targets. Mission is eligible to receive success-based milestone payments and royalty payments for each commercialized product.

https://www.biospace.com/article/releases/mission-and-abbvie-s-collaboration-in-alzheimer-s-and-parkinson-s-diseases-reaches-milestone/