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Tuesday, January 21, 2020

Glaxo balantamab mafodotin nabs accelerated review in US for myeloma

The FDA grants Priority Review status to GlaxoSmithKline’s (NYSE:GSK) marketing application for belantamab mafodotin for the treatment of relapsed/refractory multiple myeloma (MM) in patients whose prior therapies included an immunomodulatory agent, a proteasome inhibitor and an anti-CD38 antibody.
Belantamab mafodotin is an immunoconjugate comprised of a humanized anti-B cell maturation antigen monoclonal antibody conjugated to a cytotoxic agent called auristatin F via a non-cleavable linker in-licensed from Seattle Genetics (NASDAQ:SGEN).

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