Thinly traded nano cap Equillium (EQ +11.5%) is up on average volume, a modest 44K shares, diverging from Incyte’s (INCY -10.1%) selloff after itacitinib failed a late-stage study in acute graft versus host disease (GvHD).
Equillium is developing lead candidate EQ001 (itolizumab) for the same indication. A Phase 1/2 clinical trial, EQUATE, is in process with an estimated primary completion date in May 2021.
Itolizumab is a monoclonal antibody that binds to (inhibits) an immune checkpoint receptor called CD6 that plays a key role in a range of immuno-inflammatory diseases.
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