Publication on novel Saphyr-based method to analyze DNA replication in human genomes could enable new level of cancer research and drug discovery, exemplifies the importance of optical genome mapping in large research market
Bionano Genomics, Inc. (Nasdaq: BNGO), announced today the publication of a study that analyzed the mechanisms of DNA replication, a fundamental process of cell growth implicated in cancer that was previously hard to study in human genomes. The study, led by Dr. Nicholas Rhind from the University of Massachusetts Medical School with an international team of scientists from France, Canada and the USA, described a method combining optical genome mapping (OGM) with Bionano’s Saphyr® system with a labeling method developed by the scientists. The publication is available at https://www.biorxiv.org/content/10.1101/2020.08.24.263459v3.The Saphyr-based method was capable of determining the timing, speed and origin of DNA replication in human cells at a coverage level that is thousands of times higher than what earlier methods such as nanopore sequencing allowed. The breakthrough quality and quantity of single molecule data generated by Saphyr in this study illustrates the importance of novel technologies such as OGM in driving a wave of big biology and innovation in genomics.
https://finance.yahoo.com/news/bionano-genomics-announces-publication-approach-120000261.html
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