Kiniksa: Positive Results for Mavrilimumab Phase 2 Trial in Severe COVID

 – Primary endpoint achieved: the proportion of patients alive and free of mechanical ventilation at Day 29 was 12.3 percentage points higher with mavrilimumab versus placebo (p=0.1224 met predefined statistical threshold of p<0.2) –

– 65% reduction in risk of mechanical ventilation/death with mavrilimumab versus placebo (p=0.0175) –
– 61% reduction in risk of death with mavrilimumab versus placebo (p=0.0726) –
– Clinical improvement was observed on top of steroids and/or antivirals –
– Enrollment in the Phase 3 portion of the trial ongoing –

https://www.globenewswire.com/news-release/2021/04/12/2208144/0/en/Kiniksa-Announces-Positive-Results-for-Mavrilimumab-Phase-2-Trial-in-Non-Mechanically-Ventilated-Severe-COVID-19-Patients.html