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Monday, November 15, 2021

Vaxxinity, hoping to turn bodies into their own drug factories, makes Wall Street debut

 Immunotherapeutic vaccine developer Vaxxinity, with an eye on COVID and some serious CNS diseases, has pulled off a fairly small IPO.

The Dallas-based company (with bases around the world), created back in the spring when COVAXX and United Neuroscience came together under the new biotech, had been gunning for a $101 million offering, looking to sell nearly 7 million shares at a price range between $14 and $16.

But today it priced at just $13, below its original range, selling 6 million shares and earning $78 million. The company will trade on the Nasdaq under the "VAXX" symbol.

The company, tapping tech from its two parents, is working on a synthetic peptide vaccine platform—aka the Vaxxine Platform—which it said in a recent Securities and Exchange Commission filing has the potential to enable a new class of medicines.  

Its platform is set up to harness the immune system to convert the body into its own "drug factory," stimulating the production of antibodies with a therapeutic or protective effect.

It has a of host early- to midstage shots on goal, including for Alzheimer's disease, Parkinson's disease, migraine and hypercholesterolemia.

Its leading candidate, UB-311, targets amyloid to try to beat Alzheimer's, with a phase 2b early efficacy trial slated for next year.

It’s also working on a COVID-19 prevention program, UB-612, designed to activate both B- and T-cell arms of the immune system to fight against SARS-CoV-2; the program is in several phases of development around the world.

Both of these are high-risk, high-reward plays, and Vaxxinity still has a long road ahead.

https://www.fiercebiotech.com/biotech/vaxxinity-hoping-to-turn-bodies-into-their-own-drug-factories-makes-a-subdued-wall-street

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