Gritstone: Positive Initial Phase 2 Data in Late-Line Solid Tumor Patients

 -- SLATE vaccines (version 1 and SLATE-KRAS) demonstrate early evidence of efficacy with a 39% molecular response rate in evaluable patients with late-line microsatellite-stable colorectal cancer (MSS-CRC) and non-small cell lung cancer (NSCLC) --

-- Molecular response, as measured by reduction in circulating tumor DNA (ctDNA) from baseline, demonstrates a correlation with overall survival (OS) in NSCLC, consistent with industry literature --

-- SLATE-KRAS vaccine candidate elicits robust KRAS neoantigen-specific CD8+ T cell responses --

-- Data support moving SLATE-KRAS into earlier lines of treatment --

https://finance.yahoo.com/news/gritstone-presents-positive-initial-phase-110000207.html