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Wednesday, September 28, 2022

MaxCyte License to Vertex Pharma to Advance CRISPR/Cas9-based Gene-editing

 MaxCyte, Inc., (Nasdaq: MXCT; LSE: MXCT), a leading commercial cell-engineering company focused on providing enabling platform technologies to advance innovative cell-based research as well as next-generation cell therapeutic discovery, development and commercialization, today announces the signing of a strategic platform license (SPL) with Vertex Pharmaceuticals Incorporated, a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases.

Under the terms of the agreement, Vertex obtains non-exclusive clinical and commercial rights to use MaxCyte’s Flow Electroporation® technology and ExPERT™ platform in the development of its CRISPR/Cas9-based gene-edited therapy (exa-cel, formerly known as CTX001™), which entitles MaxCyte to receive platform licensing fees and program related revenue.

Exa-cel is an investigational ex vivo CRISPR gene-edited cell therapy under evaluation for patients suffering from transfusion-dependent beta thalassemia (TDT) or sickle cell disease (SCD) characterized by recurrent vaso-occlusive crises.

The same MaxCyte technology was used in the development of exa-cel under an agreement between MaxCyte and CRISPR Therapeutics.

https://www.globenewswire.com/news-release/2022/09/28/2524279/0/en/MaxCyte-Signs-Strategic-Platform-License-with-Vertex-Pharmaceuticals-to-Advance-CRISPR-Cas9-based-Gene-editing-Program.html

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