Aneurysms are weaknesses in the venous walls that require immediate attention, as they can result in the ballooning and bursting of the blood vessels. This critical medical situation is often treated using catheter-delivered blocking agents. The blocking agents are delivered into the vessels to stop blood flow in the affected area until the vessel wall can heal. The blocking material can then be removed or allowed to degrade naturally.
Existing therapies involve the placement of platinum or stainless- steel coils, but these require specialized catheters and equipment to place and detach them and can also move to other places within the blood vessels. Another procedure is to attach clips to partition off the aneurysm, but this requires open surgery and can cause narrowing of arteries due to vasoconstriction. Still other methods involve the use of liquid blocking agents injected into the blood vessels which subsequently solidify. But these agents often leak during injection, and they can also impose toxic effects and necrosis in the surrounding tissues.