Altamira Therapeutics Ltd. (NASDAQ:CYTO), a company dedicated to developing therapeutics that address important unmet medical needs, today reported that data from a recent peer-reviewed clinical study involving Bentrio nasal spray's residence time and other rheological properties demonstrated superiority vs. a saline control.
The study results are published in Drug Development and Industrial Pharmacy (Taylor & Francis) and its full text is publicly available at: https://www.tandfonline.com/doi/full/10.1080/03639045.2023.2183724
Study excerpts:
"The data presented in this study indicate that AM-301 (Bentrio) has a prolonged nasal residence time of up to 3.5 h compared to a saline control. AM-301 is a safe and well-tolerable medical device with features suitable for intranasal administration. Its nasal residence time and distribution encourage its use to protect nasopharyngeal areas. Two nasal spray applications per nostril provide no substantial benefit over a single spray with regards to coverage of the mucosal surface or nasal retention time."
"Importantly, the formulation also reached the oropharynx, remaining in place for up to 240 min compared with 60 min in the control group. This feature is particularly important, since airborne viruses and allergens come into contact with both the nasal mucosa and oropharyngeal cavity."
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