Biora Therapeutics, Inc. (Nasdaq: BIOR), the biotech company that is reimagining therapeutic delivery, today announced that it has been awarded a group of US and European patents related to several additional therapeutic targets for its NaviCap™ targeted oral delivery platform under development.
The patents are directed to methods of treating ulcerative colitis using an ingestible device that delivers one or more therapeutic agents to the proximal part of the large intestine. The patents cover a range of therapeutic targets, including Janus kinase (JAK) inhibitors, integrins, chemokines, IL-12/23 and IL-10 inhibitors, and, in some cases, cover the delivery of antibodies, peptides, small molecules, nucleic acids, stem cells, bacteria, yeast, or phages to the gastrointestinal tract.
The European Patent Office has issued European Patent No. EP3554539B1 entitled “Treatment of a disease of the gastrointestinal tract with an integrin inhibitor,” European Patent No. EP3554485B1 entitled “Treatment of a disease of the gastrointestinal tract with a JAK inhibitor and devices,” European Patent No. EP3601531B1 entitled “Treatment of a disease of the gastrointestinal tract with live biotherapeutics,” European Patent No. EP3600416B1 entitled “Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device,” and European Patent No. EP3554541B1 entitled “Treatment of a disease of the gastrointestinal tract with a chemokine/chemokine receptor inhibitor.” In addition, the European Patent Office intends to grant European Publication No. EP3554540A1 entitled “Treatment of a disease of the gastrointestinal tract with an IL-12/IL-23 inhibitor released using an ingestible device.”
The U.S. Patent and Trademark Office has issued US Patent No. 11,597,762 entitled “Treatment of a disease of the gastrointestinal tract with an IL-12/IL-23 inhibitor released using an ingestible device,” US Patent No. 11,426,566 entitled “Treatment of a disease of the gastrointestinal tract with a TLR modulator,” US Patent No. 11,523,772 entitled “Treatment of a disease of the gastrointestinal tract with an immunosuppressant,” and US Patent No. 11,596,670 entitled “Treatment of a disease of the gastrointestinal tract with IL-10 or an IL-10 agonist.”
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