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Monday, September 11, 2023

Mineralys: Phase 2 Trial Results for Lorundrostat in Uncontrolled and Treatment-Resistant Hypertension

 

  • Lorundrostat, a highly selective aldosterone synthase inhibitor, demonstrated robust, double-digit reduction in systolic blood pressure (BP) with a well-tolerated profile
  • Enhanced reduction in systolic BP seen in individuals with elevated body mass index (BMI)
  • Robust trial design and results led to lorundrostat being first of new class, aldosterone synthase inhibitors, to start pivotal clinical program in hypertension

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