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Wednesday, September 13, 2023

Ocugen: Positive Update in Phase 1/2 Trial of Gene Therapy Product Candidate for Retinitis Pigmentosa

 

  • Favorable safety and tolerability profile of OCU400 investigational drug product in RP and LCA subjects to date

  • Clinical study update suggests continued positive trends in Best-Corrected Visual Acuity (BCVA) and Multi-Luminance Mobility Testing (MLMT), as well as positive trends in Low-Luminance Visual Acuity (LLVA) among treated eyes

  • 83% (10/12) of subjects demonstrated stabilization or improvement in treated eye either on BCVA or LLVA or MLMT scores from baseline

  • Notably, 86% (6/7) of RHO mutation subjects experienced either stabilization of or increase in MLMT scores from baseline including a subset of 29% (2/7) that demonstrated a 3 Lux luminance level improvement

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