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Thursday, May 8, 2025

Intellia First Quarter 2025 Financial Results, Recent Company Progress

Intellia Therapeutics (NASDAQ:NTLA) reported its Q1 2025 financial results and clinical progress. The company is advancing three key Phase 3 trials: HAELO study for hereditary angioedema (HAE), MAGNITUDE-2 for hereditary ATTR amyloidosis with polyneuropathy, and MAGNITUDE for ATTR with cardiomyopathy. Financial highlights include a cash position of $707.1M expected to fund operations into H1 2027, though this represents a decrease from $861.7M in Q4 2024. Q1 revenue was $16.6M, down from $28.9M year-over-year, with a net loss of $114.3M. Clinical milestones include completing HAELO study enrollment in Q3 2025, presenting additional NTLA-2002 Phase 1 data at EAACI Congress in June, and sharing longer-term data for both ATTR-CM and ATTRv-PN patients in H2 2025. The company's lead programs utilize CRISPR-based gene editing technology delivered through lipid nanoparticles.

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