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Thursday, March 4, 2021

Fulcrum ends covid med trial

 After careful consideration, Fulcrum is discontinuing LOSVID, a Phase 3 trial with losmapimod for hospitalized subjects with COVID-19, due to significant changes in the COVID-19 treatment paradigm, including new therapeutic options and emerging vaccines.

  • The company has decided to redeploy its resources to other clinical programs and discovery efforts, with a continued focus on rare diseases.
  • Losmapimod was generally well tolerated in LOSVID, and an independent data safety monitoring board did not identify any safety concerns related to losmapimod.

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