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Thursday, June 3, 2021

NANOBIOTIX Reports New Data for Potential First-in-Class Radioenhancer NBTXR3 Combo

 Data to be Presented at the 2021 Annual Meeting of the American Society for Clinical Oncology

  • Results show NBTXR3 plus radiotherapy could potentially stimulate immune response and convert anti-PD-1 non-responders into responders
  • Objective response was observed in 60% of anti-PD-1 naïve patients and 50% of prior non-responders
  • Data suggest abscopal effect in some patients (i.e., reduction in non-injected / non-irradiated lesions)
  • To date, the overall adverse event profile for the 16 injected patients has not differed from what is expected with radiotherapy or anti-PD-1 agents (head and neck cancer and non-small cell lung cancer primary tumors)
  • New readout could provide promising signals for NBTXR3 as a potential pillar of immunotherapy
  • Following ASCO, Nanobiotix will host an investor event on Friday, June 11, 2021 at 8:00 am Eastern Time (14:00 Central European Time), to provide an in-depth review of the immunotherapy data with several key opinion leaders including study investigators (Register here)

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