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Tuesday, February 15, 2022

Lilly Unites With ImmunoGen In ADC Deal Worth Up To $1.7B

 mmunoGen Inc 

 (Get Free Alerts for IMGN) has struck a multi-target license deal with Eli Lilly And Co  (Get Free Alerts for LLY) to grant exclusive rights to research, develop, and commercialize antibody-drug conjugates (ADCs) directed to targets selected by Lilly based on ImmunoGen's camptothecin technology.

  • Camptothecins are an important class of anticancer drugs targeting Type I topoisomerase.
  • According to the deal, Lilly will pay ImmunoGen an upfront payment of $13 million, reflecting initial targets selected by Lilly.
  • Lilly may select a pre-specified number of additional targets, with ImmunoGen eligible to receive an additional $32.5 million in exercise fees if Lilly licenses the full number of targets.
  • ImmunoGen can receive up to $1.7 billion in potential target program exercise fees and milestone payments.
  • ImmunoGen is also eligible for tiered royalties as a percentage of worldwide commercial sales by Lilly. 
  • Lilly is responsible for all costs associated with research and development.
  • ImmunoGen retains full rights to the camptothecin platform for all targets not covered by the Lilly license.

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