Cyclacel Phase 1 Data Suggests Efficacy Against Certain Tumors

 - Patient Pharmacodynamic Data Show Decrease in CDKN2A, CDKN2B, and PRMT5 Protein Levels -

- A Squamous Non-Small Cell Lung Cancer Patient with CDKN2B Deletion Achieved Marked Tumor Shrinkage after One Cycle -

- Retrospective Analysis Identified CDKN2A, CDKN2B and/or MTAP Deletions in Four Patients Previously Dosed with Fadra Achieving Responses or Stable Disease -

- Forthcoming Phase 2 Study to Further Evaluate Fadra Efficacy -

https://www.globenewswire.com/news-release/2023/12/18/2797893/10564/en/Cyclacel-Pharmaceuticals-Reports-Fadraciclib-Phase-1-Data-Suggesting-Efficacy-Against-Tumors-With-CDKN2A-CDKN2B-and-MTAP-Deletions.html