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Friday, June 7, 2019

Germany’s Stada buys six of GSK’s consumer brands, eyes further deals

Private equity-backed generic drugmaker Stada said on Friday it would buy six consumer healthcare products from British drugmaker GlaxoSmithKline to bolster its presence in Europe.

The price tag for the mainly Europe-focused brand portfolio, which include itch relief cream Eurax, antiseptic cream Savlon and Tixylix cough liquids, was in the high double digit million pound range, according to a person close to the deal.
Stada declined to comment on the price.
GSK is streamlining its product offering as it prepares to fold its consumer business into a joint venture with Pfizer by the second half of this year, creating a market leader that will primarily look to the United States and China for growth.
Stada CEO Peter Goldschmidt said the company, which will fold the brands into its British Thornton & Ross unit, would bring to bear its knowledge of complex European healthcare markets that some global players are lacking, also with a view to future deals or alliances.
“We have a strong presence in almost all the European countries, there are not many companies where that is the case. For companies in, say, the United States, India or China that are looking for a European partner we are the go-to partner,” the CEO told Reuters.
The German company, majority owned by buyout firms Bain and Cinven since 2017, reported adjusted earnings before interest, taxes, depreciation and amortization (EBITDA) of just over 500 million euros last year on sales of 2.3 billion euros.

Gene editors rally on Vertex/Crispr deal

CRISPR/Cas9 gene editors Intellia Therapeutics (NTLA +4.6%) and Editas Medicine (EDIT +8.4%) are enjoying a spike in demand after Vertex Pharmaceuticals in-licensed the technology from CRISPR Therapeutics (CRSP+15%) to develop gene therapies for Duchenne muscular dystrophy and myotonic dystrophy Type 1.

Lilly petitions Supreme Court to protect Cialis BPH patent

FiercePharma reports that Eli Lilly (LLY +1%) has petitioned the Supreme Court to reconsider a lower court decision invalidating a Cialis (tadalafil) patent for benign prostatic hyperplasia or BPH (enlarged prostate).
The patent was invalidated after being challenged by an entity in Germany that Lilly calls “shadowy.”
The company is hoping that SCOTUS will agree to hear the case (and reverse the decision) which may stem the continued erosion in sales. In Q1, for example, Cialis sales were down 38% to $308.2M. In Q1 2017, sales were $533.6M (-7.5%).

FDA OKs expanded use for PTC’s Emflaza

The FDA has approved the use of PTC Therapeutics’ (PTCT +3%) Emflaza (deflazacort) in Duchenne muscular dystrophy (DMD) patients as young as two years old.
The agency first approved the corticosteroid in February 2017 for DMD patients at least five years old.

DaVita up 2.5% on expected FTC nod on sale of doctor unit

DaVita (DVA +2.5%) is up on below-average volume in apparent response to a report from Capital Forum that the Federal Trade Commission (FTC) staff reviewing the planned sale of its Medical Group unit to UnitedHealth (UNH +1.7%) will give a thumbs up on the $4.34B deal.

FDA extends action date 90 days for Xeris Pharma’s glucagon rescue pen

The FDA has extended its action date to September 10 for its review of Xeris Pharmaceuticals’ (NASDAQ:XERS) marking application for Gvoke (ready-to-use glucagon injection) for the treatment of severe hypoglycemia (low blood sugar).
The 90-day extension is standard operating procedure for the agency when there is a major amendment to an NDA. In this case, additional information requested by the review team constituted such an amendment.

Stoke Therapeutics readies $100M IPO

Stoke Therapeutics (STOK) has filed a prospectus for an IPO of 6.7M common shares at $14 – 16. The offering will be valued at $100.5M at the midpoint.