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Thursday, March 7, 2024

Biden looks like a loser on the eve of his State of the Union

 There’s a creepy video of Joe Biden this week in which he gets right in the face of a reporter who dares ask about his catastrophic poll numbers — and then he flat-out lies, as if presidential vehemence can overwhelm the truth. 

The president was about to board Air Force One after another four-day weekend at Camp David. 

President Biden won the Democratic caucuses in Hawaii on Wednesday, moving him closer to winning his party’s nomination again after romping through the Super Tuesday contests earlier this week.ZUMAPRESS.com

“What’s your message for Democrats who are concerned about your poll numbers?” he was asked by one of the reporters waiting on the tarmac. 

Biden squinted and frowned before leaning into the lie: “The last five polls you guys don’t report. I’m winning! Five! Five in a row!” 

What’s he been smoking at Camp David? 

On the eve of his State of the Union address Thursday, Biden looks like a loser. 

His kingdom of lies is crumbling. 

Americans belatedly are waking up to the border disaster he inflicted on the country, the rancor and division he stoked, the preposterous wokery he imposed on every corner of the government, the incompetence, the wars, the “Bidenomics” that translated to empty wallets. 

Almost two-thirds of voters think the country is heading in the wrong direction, according to the latest New York Times-Siena College poll, one of four bad polls over the last week that show the stubborn verdict of the country is against Biden. 

President Biden lied about his poll numbers when he got in the face of a reporter who asked about them, according to reports.Getty Images

He’s too old, too divisive, the country’s going in the wrong direction and we’re all worse off than we were under Donald Trump

Biden’s ‘truth’ 

It’s not the first time he’s gaslit reporters about his horrible poll numbers.

Do Biden’s staffers encourage his fantasies by giving him pretend polls showing he’s doing great? 

Maybe his choice of breakfast TV explains his delusional thinking.

Reportedly, he just loves MSNBC’s “Morning Joe.” 

You can see why from this small sample of host Joe Scarborough’s pungent political analysis this week:

“I undersold [Biden] when I said he was cogent … He is better than he has ever been … F–k you if you can’t handle the truth. This version of Biden, intellectually, analytically, is the best Biden ever. Not a close second and I’ve known him for years … If it weren’t the truth, I wouldn’t say it.” 

President Biden speaks to the press before boarding Air Force One at Hagerstown Regional Airport in Hagerstown, Maryland, on March 5, 2024.REUTERS

Let’s call it Joe’s “truth.” 

Meanwhile, in the real world, Biden’s fallen four points behind the dreaded Trump in the NYT-Siena poll, despite all the lawfare and slander Democrats have rained down on the former president’s head. 

While 40% of voters said Trump’s policies had helped them personally, just 18% said the same about Biden.

A Fox News poll found 48% of voters say Biden’s policies have hurt them, while only 32% say the same for Trump’s. 

A CBS News/YouGov poll found almost half (46%) of voters say Trump’s presidency is “good” and “excellent,” while only about one-third of voters say the same for Biden. 

Fully 61% of voters say Biden is too old to be an effective leader — and that’s not just a numerical verdict.

He is not a sprightly 81.

He is cognitively and physically falling apart in front of our eyes.

He has not developed wisdom with age. 

If anything, he’s more feckless and disengaged than ever. 

The selfishness of clinging on for a second term is typical Biden, as is the fact that his handpicked DEI vice president offers no release valve. 

It serves the Democrats right.

They rigged things to inflict this historically woeful president on the country and now are hoist by their own petard. 

Biden’s inability to acknowledge fault and accept responsibility means there will be no policy reset Thursday night, just a refurbishing of the old narrative that it’s all Trump’s fault. 

Big, bad MAGA!

Democracy is at stake!

Character is on the ballot!

Yeah, yeah, we’ve heard it all before. 

Reportedly, Biden plans to offer a “unity” agenda. 

When asked about the poll numbers, Biden said, “The last five polls you guys don’t report. I’m winning! Five! Five in a row!” AP

Really?

After three years of inciting hatred against white conservatives and pitting Americans against each other for base political advantage, he’s sticking to the story that he’s a unifier? 

Will he apologize for opening the floodgates to the Third World’s worst rapists, murderers, terrorists, con artists and freeloaders? 

Will he apologize to the family of Laken Riley

Will he apologize to the horseback Border Patrol agents he falsely accused of whipping Haitian migrants? 

Will he apologize to the families of the 13 US military members killed in his botched Afghanistan withdrawal? 

Coming home to roost 

Will he apologize to the Secret Service agents attacked by his out-of-control German shepherds for months on end? 

Will he apologize for lying about his involvement in his son’s influence-peddling schemes, and claiming Hunter’s laptop was a “Russian plant”? 

Of course not. 

Instead, his campaign issued a statement after Trump’s Super Tuesday victory clinched the Republican nomination. 

President Biden arrives to board Air Force One on March 5, 2024, in Hagerstown, Md.AP

“Donald Trump Limps Into the General Election as a Wounded, Dangerous and Unpopular Candidate.” 

Trump is only limping and wounded because Biden’s surrogates have been attacking him with lawfare.

And how’s that really working out? 

In Georgia, Fani Willis has descended into farce. 

In New York, Alvin Bragg’s case rests on the word of perjurer and convicted felon Michael Cohen. 

Jack Smith’s classified document case was blown up by the kid-glove treatment of Biden’s more egregious mishandling of top secret material. 

It’s not the first time President Biden has gaslit reporters about his horrible poll numbers.REUTERS

And the Supreme Court just put a stick in the wheel of Smith’s insurrection frame-up. 

E. Jean Carroll is the best they can do.

A nut who says rape is “sexy” and has a cat named Vagina. 

It’s an embarrassment. 

They thought they could foist a subpar candidate on America for the second election in a row by crippling Trump legally and ruining him financially.

But the whole lawfare gambit backfired on them. 

The more they piled on, the more his poll ratings went up.

Even people who don’t approve of Trump can see the injustice and know that they could be next. 

Biden’s chickens finally are coming home to roost.

https://nypost.com/2024/03/06/opinion/joe-biden-looks-like-a-loser-on-the-eve-of-his-state-of-the-union/

Avid hit on prelims

 Avid Bioservices, Inc. (NASDAQ:CDMO), a dedicated biologics contract development and manufacturing organization (CDMO) working to improve patient lives by providing high quality development and manufacturing services to biotechnology and pharmaceutical companies, today announced preliminary earnings estimates for the third quarter and nine months ended January 31, 2024.

The company expects results in the third quarter of fiscal 2024 to include:

Revenues & Backlog

  • Revenues for the third quarter of fiscal 2024 were $33.8 million, representing an 11% decrease as compared to revenues of $38.0 million recorded in the same prior year period and a 33% increase as compared to revenues of $25.4 million recorded in the second quarter of fiscal 2024. For the first nine months of fiscal 2024, revenues were $96.9 million, a decrease of approximately 11% compared to $109.5 million in the same prior year period. The decrease in revenues for the third quarter and nine months ended January 31, 2024 compared to the same prior year periods was primarily attributed to fewer manufacturing runs and a reduction in process development services from early-stage customers. Additionally, the first nine months revenues were also impacted by a reduction of revenue for changes in estimated variable consideration under a contract where uncertainties have been resolved.

  • The company’s commercial team signed multiple new orders during the third quarter of fiscal 2024, totaling approximately $41 million net, and resulting in record high revenue backlog of $206 million, representing an increase of 17% compared to $176 million at the end of the same quarter last year. These orders span a broad range of the company’s capabilities and are primarily from later-stage projects. The company anticipates a significant amount of its backlog will be recognized as revenue over the next five fiscal quarters.

Gross Profit

  • Gross profit for the third quarter of fiscal 2024 was $2.4 million (7% gross margin), compared to $9.8 million (26% gross margin) in the third quarter of fiscal 2023 and a gross loss of $4.7 million (negative 18% gross margin) in the second quarter of fiscal 2024. Gross profit for the first nine months of fiscal 2024 was $1.8 million (2% gross margin), compared to a gross profit of $23.1 million (21% gross margin) for the same period during fiscal 2023.   The decrease in gross margin for the three and nine months ended January 31, 2024 compared to the same prior year periods was primarily driven by fewer manufacturing runs, a reduction in process development services from early-stage customers, and an increase in our costs related to expansions of both the company’s capacity and technical capabilities.  Gross margins during the nine months ended January 31, 2024, were also impacted by a reduction of revenue for changes in estimated variable consideration under a contract where uncertainties have been resolved, a terminated project relating to the insolvency of one of the company’s smaller customers, and a delay in the ability to recognize revenues of a customer product pending the implementation of a process change.

Selling, General and Administrative (SG&A) Expenses

  • SG&A expenses for the third quarter of fiscal 2024 were $6.4 million, a decrease of 10% compared to $7.1 million recorded for the third quarter of fiscal 2023 and a decrease of 3% compared to $6.6 million recorded for the second quarter of fiscal 2024. SG&A expenses for the first nine months of fiscal 2024 were $19.2 million, a decrease of approximately 6% compared to $20.3 million recorded in the same prior year period. The decrease in SG&A for both the three and nine months ended January 31, 2024 compared to the same prior year periods was primarily due to decreases in compensation and benefit related expenses, and consulting fees.

Operating Income (Loss)

  • Operating loss for the third quarter of fiscal 2024 was $4.0 million, a decrease compared to operating income of $2.7 million recorded for the third quarter of fiscal 2023 and an increase compared to an operating loss of $11.2 million recorded for the second quarter of fiscal 2024. Operating loss for first nine months of fiscal 2024 was $17.4 million compared to operating income of $2.8 million for the first nine months of fiscal 2023. The decrease in operating income for the three and nine months ended January 31, 2024 compared to the same prior year periods was driven by a decrease in gross profit partially offset by reduced SG&A.

Other Items

  • The company is maintaining revenue guidance for full fiscal year 2024 of $137mm to $147mm.

  • On January 31, 2024, Avid reported cash and cash equivalents of $30.7 million, compared to $38.5 million on April 30, 2023.

  • During the quarter, Avid marked the completion of its cell and gene therapy (or CGT) facility, representing the final step in a three-year expansion program that has dramatically increased the company’s service offerings and revenue generating capacity. Avid estimates that its combined mammalian and CGT facilities now have a total revenue generating capacity of up to approximately $400mm annually.

Neumora Financial Results and Business Update

 On-track to report topline Phase 3 data from the KOASTAL-1 study with navacaprant in MDD in the second half of 2024 and Phase 1 data with NMRA-266 in healthy adult participants mid-2024

Strong financial position with $463.8 million in cash, cash equivalents and marketable securities expected to support operations into 2026

https://www.biospace.com/article/releases/neumora-therapeutics-reports-fourth-quarter-and-full-year-2023-financial-results-and-provides-business-update/

Solid Biosciences in Licensing Agreement with Armatus

 Solid Biosciences Inc. (Nasdaq: SLDB), a life sciences company developing precision genetic medicines for neuromuscular and cardiac diseases, today announced a non-exclusive worldwide license and collaboration agreement with Armatus Bio for the use of Solid’s proprietary capsid AAV-SLB101 for the development and commercialization of Armatus’ vectorized RNAi candidate to treat Facioscapulohumeral muscular dystrophy (FSHD). The AAV-SLB101 capsid has been shown in preclinical studies to have enhanced biodistribution and improved expression in muscle cells.

Under the terms of the agreement, Solid granted Armatus a non-exclusive worldwide license to utilize AAV-SLB101 for treatment of FSHD and will provide Armatus AAV-SLB101 plasmid material, preclinical data characterizing AAV-SLB101, and manufacturing and regulatory know-how to enable development. In return, Solid will receive an upfront payment, payments upon the achievement of certain development and sales milestones, and tiered royalties on net sales for any products incorporating AAV-SLB101. Armatus will be responsible for the development and commercialization of licensed products incorporating AAV-SLB101.

https://www.biospace.com/article/releases/solid-biosciences-announces-licensing-agreement-with-armatus-bio-for-the-use-of-aav-slb101-a-proprietary-muscle-targeted-capsid-in-the-development-of-an-rnai-therapy-to-treat-fshd/