African 'hotspot' for highly infectious diseases

 A regional corner of Africa is a hotspot for cases of HIV, tuberculosis and malaria, prompting researchers to call for targeted health support rather than a national response.

The new research, published today in BMJ Global Health, found a high prevalence of all three infectious diseases in the Gambela region, a regional centre located in western Ethiopia that borders South Sudan.

Lead author Dr Kefyalew Alene, from the Curtin School of Population Health and the Telethon Kids Institute, said it was concerning to find one region reporting large numbers of all three diseases.

"Human immunodeficiency virus (HIV), tuberculosis and malaria are the three most serious infectious diseases in the world, causing high morbidity and mortality rates especially in low and middle-income countries," Dr Alene said.

"This study identified that the Ethiopian region of Gambela, which is home to more than 330,000 people, was a hotspot for high cases of HIV, tuberculosis and malaria. The high prevalence of HIV, tuberculosis and malaria in this region may be due to inadequate case management and weaker health systems along the border."

The study found the Gambela region was characterised by low healthcare access, low socioeconomic index, and high temperatures and rainfall.

Dr Alene said the study suggested the need for more targeted health services to deal with the spate of cases concentrated to one part of Africa.

"This highlights that targeting health services at a local level would be more effective than a nation-wide service response," Dr Alene said.

"These findings can guide policymakers in Ethiopia to design geographically targeted and integrated disease control programs to achieve maximum impact in addressing the high prevalence of cases."

The research was co-authored by other experts from Curtin and the Telethon Kids Institute, as well as Ethiopia's University of Gondar and the National TB Control Program.

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Materials provided by Curtin University. Note: Content may be edited for style and length.

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Journal Reference:

1. Kefyalew Addis Alene, Ahmed Elagali, Dylan D Barth, Susan F Rumisha, Punam Amratia, Daniel J Weiss, Kendalem Asmare Atalell, Andargachew Kumsa Erena, Peter W Gething, Archie C A Clements. Spatial codistribution of HIV, tuberculosis and malaria in Ethiopia. BMJ Global Health, 2022; 7 (2): e007599 DOI: 10.1136/bmjgh-2021-007599

https://www.sciencedaily.com/releases/2022/02/220225085901.htm