Revelation Biosciences Surges After Encouraging Data From Allergic Rhinitis Study
- Revelation Biosciences Inc announced topline data for its Phase 1b CLEAR study to evaluate the effect of intranasal REVTx-99b on nasal challenge allergen in participants with allergic rhinitis to rye grass pollen.
- The study met the primary endpoint evaluating the effects of REVTx-99b versus placebo on safety and tolerability.
- Exploratory endpoints for efficacy were not met, including no reduction in allergy symptoms and increase in peak nasal inspiratory flow versus placebo.
- Revelation management plans to evaluate the future development of this and other ongoing programs.
- REVTx-99b is a proprietary intranasal formulation in development for managing allergic rhinitis symptoms, including chronic nasal congestion.
- Phase 2b viral challenge study data announced in March showed that REVTx-99a did not meet its primary endpoint, the area under the curve of viral load by quantitative RT-PCR from nasopharyngeal swabs.
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