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Thursday, March 6, 2025

Zuckerberg helped China develop censor tools, hid CCP ties from Congress: ex-employee’s memoir

 Meta CEO Mark Zuckerberg is a “careless” executive who sought to convince China to let his company operate on the mainland by helping it develop censorship tools and bolster its artificial intelligence capabilities — all while concealing those efforts from Congress, according to a new memoir.

Sarah Wynn-Williams, a former Meta employee who worked at Facebook for seven years before the social media giant rebranded as Meta, is the author of “Careless People: A Cautionary Tale of Power, Greed, and Lost Idealism.”

The book detailed an alleged “rotten company culture” that included “shocking accounts of misogyny and double standards” under Zuckerberg and ex-No. 2 Sheryl Sandberg, who were described as “callously indifferent to the price others would pay for their own enrichment.”

Sarah Wynn-Williams is a former Meta employee who worked at Facebook for seven years.courtesy.

Wynn-Williams, the former director of global public policy at Facebook, left the company in 2018.

“We haven’t seen the book, but this former employee was terminated in 2017 and an investigation at that time found she made false claims,” a Meta spokesperson told The Post.

“As Mark himself said in a televised address in 2019, ‘[He] wanted our services in China … and worked hard to make this happen. But we could never come to agreement on what it would take for us to operate there.’ That is why we don’t operate our services in China today,” the Meta spokesperson added.

Described by publisher Flatiron Books as “a deeply personal account of why and how things have gone so horribly wrong in the past decade,” the memoir claims to shed light on the company’s leadership and culture.

The book is also being published by Pan Macmillan in the United Kingdom, whose website calls the book “an explosive dispatch from someone who had a front-row seat to the inner workings of one of the most influential companies on the planet.”

Wynn-Williams “takes readers inside Meta’s board rooms, private jets, and meetings with heads of state, revealing the appetites, excesses, blind spots, and priorities of executives Mark Zuckerberg, Sheryl Sandberg, and Joel Kaplan.”

According to Pan Macmillan, the trio of executives are portrayed as “profoundly flawed, self-interested, and careless human beings.”

Wynn-Williams is the author of “Careless People: A Cautionary Tale of Power, Greed, and Lost Idealism.”Barnes & Noble

The more power the three executives amassed, “the less responsible they became, with far-reaching consequences that continue to this day.”

Pan Macmillan promises the “previously unreported lengths to which Mark Zuckerberg went to convince the Chinese Communist Party to allow Meta to operate in China.”

According to Wynn-Williams, those efforts included “providing briefings to CCP officials on new technologies like artificial intelligence, developing bespoke censorship tools with the CCP, and making efforts to hide Meta’s cooperation with the CCP from the United States Congress.”

Wynn-Williams also takes aim at the company for failling to stop “genocide-fueling lies” overseas as well as for “shocking accounts of workplace harassment and misogyny.”

The book is said to contain details about the “previously unreported lengths to which Mark Zuckerberg went to convince the Chinese Communist Party to allow Meta to operate in China.”Getty Images

The book also singles out Sandberg for not addressing “the grueling demands and humiliations of working motherhood” while she was winning “international acclaim for urging women to ‘Lean In.'”

The book is available for preorder through retailers such as Bookshop.org, Barnes & Noble, and Amazon.

Notably, its release was kept under tight wraps, with Flatiron announcing the book less than a week before publication.

Amazon’s listing initially carried the vague placeholder title “Untitled-Flatiron-Author-Revealed-March.”

Zuckerberg has made multiple attempts to expand Facebook’s presence in China, despite the country’s strict internet regulations and the platform being blocked there since 2009.

The book also singles out former Meta executive Sheryl Sandberg for not addressing “the grueling demands and humiliations of working motherhood” while she was winning “international acclaim for urging women to ‘Lean In.'”Getty Images

He courted Chinese officials by learning Mandarin, meeting with government leaders, and even jogging through Beijing’s Tiananmen Square in a widely publicized visit.

Despite these efforts, Facebook was unable to gain entry into the Chinese market, as the government maintained its strict control over foreign tech companies and digital censorship.

In 2016, the New York Times revealed that Facebook had created software that would allow a third party, likely a Chinese partner, to suppress certain posts from appearing in specific geographic areas.

The tool was designed to comply with China’s strict internet regulations, but its existence sparked internal debates at Facebook, with some employees expressing concerns over its implications for free speech.

Ultimately, Facebook never launched the tool, and the company’s efforts to enter China remained unsuccessful.

In a 2019 speech at Georgetown University, Zuckerberg said the company’s refusal to bow to China’s censorship demand is one of the factors that led to its continued absence from the country.

Joel Kaplan, Meta’s vice president of global public policy, is also described in the book as “callously indifferent.”Getty Images

“It’s one of the reasons we don’t operate Facebook, Instagram or our other services in China,” Zuckerberg said in the 2019 speech.

“I wanted our services in China because I believe in connecting the whole world and I thought we might help create a more open society.”

Zuckerberg said he “worked hard to make this happen. But we could never come to agreement on what it would take for us to operate there, and they never let us in.”

“And now we have more freedom to speak out and stand up for the values we believe in and fight for free expression around the world.”

Wynn-Williams, a diplomat and policy expert, has also served as the chief negotiator for the United Nations on biosafety liability, according to her bio on the World Economic Forum.

Sandberg joined Facebook as chief operating officer in 2008, becoming a key figure in transforming the company into a global advertising powerhouse.

Before Facebook, she held leadership roles at Google and served as chief of staff for the US Treasury Department under President Bill Clinton. At Facebook, she was instrumental in scaling its ad business and shaping its corporate culture, often advocating for gender equality in the workplace.

In 2013, Sandberg published “Lean In: Women, Work, and the Will to Lead,” which became a bestseller and sparked discussions about women’s leadership and career advancement.

Zuckerberg sought to win approval from Chinese authorities to operate in the mainland.Bloomberg via Getty Images

The book encouraged women to take initiative in their professional lives but also faced criticism for overlooking structural barriers that many women face.

During her tenure, Facebook faced scrutiny over data privacy issues, misinformation, and its role in political controversies, including the Cambridge Analytica scandal. Sandberg defended the company but later admitted to missteps.

In June 2022, she announced her departure from Meta — stepping down after 14 years. While she cited a desire to focus on philanthropy and personal projects, reports suggested internal tensions and growing regulatory pressures played a role in her exit.

Kaplan is Meta’s vice president of global public policy and a former White House deputy chief of staff under President George W. Bush.

At Meta, he has played a key role in shaping the company’s political strategy, often advocating for conservative perspectives and influencing content moderation policies.

A spokesperson for Sandberg declined to comment.

https://nypost.com/2025/03/06/business/mark-zuckerberg-hid-ties-to-chinas-communist-party-from-congress-memoir/

South Korea prepared to freeze new medical student numbers, minister says

 South Korea's education ministry said on Friday it had agreed to freeze the number of new medical students at about 3,000 per year in a bid to end a 13-month dispute involving a walkout by trainee doctors and boycotting of classes.

Education minister Lee Ju-ho said, however, that the plan could only go ahead if all of the trainee doctors returned.

https://www.usnews.com/news/world/articles/2025-03-07/south-korea-prepared-to-freeze-new-medical-student-numbers-minister-says

Could A Bombshell Discovery Render All of Biden's Presidential Actions 'Null and Void'?

 by Matt Margolis via PJ Media,

The Biden presidency might have been the greatest con job ever perpetrated on the American people. A shocking investigation by the Heritage Foundation's Oversight Project has revealed that virtually every document bearing Joe Biden's signature during his presidency was signed by an autopen — except for one.

Mandel Ngan/Pool via AP

What makes this revelation particularly damning is that the only document confirmed to have Biden's actual signature was his letter announcing his withdrawal from the 2024 presidential race. Let that sink in for a moment.

Remember when House Speaker Mike Johnson (R-La.) revealed his discussion with Biden when Biden couldn't recall signing the executive order halting LNG exports? Now we know why — he probably didn't. The real question is: Who did? Who was running the country while Biden was not all there?

The use of the presidential autopen dates back to the 1950s, and there's been much debate about its legality. In 2013, Barack Obama became the first president to sign a bill into law using an autopen. He was vacationing in Hawaii at the time. His office relied on a 30-page memo from President George W. Bush's legal team asserting that the president's presence was not required as long as said president had authorized the signature. 

What's not clear, in the case of Biden, is who was running the autopen and whether Biden was aware it was happening. 

Missouri Attorney General Andrew Bailey is demanding that the Department of Justice investigate whether Biden's obvious cognitive decline allowed unelected bureaucrats to essentially run the government without presidential oversight. If this is true — and let's be honest, all signs point to yes — every executive order, every pardon, and every official action taken under Biden's name could be constitutionally void.

Bailey's letter to Michael E. Horowitz, the inspector general of the Department of Justice, spells it out perfectly.

I write to request that you conduct a full investigation into President Biden's mental capacity in his final days in office. By now, Biden's mental decline is famous. Under the 25th Amendment, his inability to make decisions should have meant a succession of power. Instead, it appears staffers and officers in the Biden administration may have exploited Biden's incapacity so they could issue orders without an accountable President of sound mind approving them. That would explain why the Biden administration's orders were aggressively much farther to the left than any previous President. If in fact Biden's staffers were exploiting his mental decline, those orders are null and void.

The evidence is overwhelming. We know that Biden's handlers desperately tried to prevent anyone from meeting with him one-on-one. Even Democratic insiders admit the truth. DNC fundraiser Lindy Li recently spilled the beans and acknowledged that Biden wasn't running the show; his staff, his wife, and Hunter were.

Thanks to the Heritage Foundation's investigation, we now have proof that Biden's signature was automated throughout his presidency — which raises serious questions about whether he was aware of what was being signed in his name at all. The Oversight Project rightfully points out that since Biden revoked Trump's executive privilege, we can easily determine who controlled the autopen and what safeguards, if any, were in place.

The implications are staggering. We essentially had a presidency by proxy, with unelected staffers wielding presidential power while the man himself was barely cognizant enough to read a teleprompter. This isn't just a scandal; it's potentially the biggest constitutional crisis in American history.

The American people deserve to know who was really calling the shots during the Biden administration. If these allegations prove true, every single action taken under Biden's name needs to be scrutinized and potentially nullified. The truth must come out, and those responsible must be held accountable. 

https://www.zerohedge.com/political/could-bombshell-discovery-render-all-bidens-presidential-actions-null-and-void

Brain-mapping technique identifies memory cells vulnerable to Alzheimer's protein buildup

 Researchers from The University of Texas at Arlington and the University of California–San Francisco have used a new brain-mapping technique to identify memory-related brain cells vulnerable to protein buildup, a key factor in the development of Alzheimer's disease, an incurable, progressive brain disorder that slowly destroys memory and thinking skills.

In Texas, nearly half a million people live with Alzheimer's disease, a form of dementia that costs the state approximately $24 billion in caregiver time, according to the Texas Department of State Health Services. Texas ranks fourth in the nation for Alzheimer's cases and second in Alzheimer's-related deaths.

To understand why certain parts of the brain are more affected by Alzheimer's disease, researchers focused on tau, a protein that accumulates in brain cells and disrupts normal activity. Using the MISS (Matrix Inversion and Subset Selection) mapping technique, which profiled approximately 1.3 million cells, the research team created detailed maps of different cell types in the brains of mice. They compared these maps to areas where tau builds up to identify which cell types are most affected. Their findings are published in Communications Biology.

"Using mathematical and computational models, we found that certain cells in the hippocampus, a brain area important for memory and navigation, are more vulnerable to tau buildup," said author Pedro Maia, an assistant professor of mathematics at UTA.

Brain mapping unlocks key Alzheimer's insights
Univariate analysis of the relationship between AD risk genes and end-time-point pathology across mouse tauopathy models. Credit: Communications Biology (2025). DOI: 10.1038/s42003-025-07575-1

"These glutamatergic neurons showed a strong connection with tau deposits, meaning they are more likely to be affected. In contrast, brain cells in the cortex—the part of the brain that controls movement, , emotions and reasoning—were less likely to be affected by tau."

Interestingly, the researchers also discovered that oligodendrocytes,  that help insulate nerve fibers, were less affected by tau. This suggests that these cells might help to protect the brain against tau buildup.

The study also found that the distribution of different cell types in the brain may better predict where tau accumulation occurs than genetic factors alone. This implies that the types of cells present in different brain regions may be more important than Alzheimer's-related genes in determining vulnerability to tau.

"Overall, this study helps us understand why certain  are more affected by tau buildup leading to Alzheimer's disease," Dr. Maia said.

"By identifying the cell types and gene functions involved, our study showcases how theoretical and computational models can provide new insights into the progression of Alzheimer's disease. This is another piece of valuable data that will help us specifically target the vulnerable cells and genes associated with tau buildup, potentially slowing or preventing Alzheimer's disease progression in the future."

More information: Justin Torok et al, Searching for the cellular underpinnings of the selective vulnerability to tauopathic insults in Alzheimer's disease, Communications Biology (2025). DOI: 10.1038/s42003-025-07575-1


https://medicalxpress.com/news/2025-03-brain-technique-memory-cells-vulnerable.html

Neurostimulation shows promise as potential Alzheimer's treatment in preliminary trial

 Repeated sessions of electrical stimulation to brain networks associated with memory improved verbal learning in some Alzheimer's disease patients for up to eight weeks in a preliminary trial led by UT Southwestern Medical Center researchers. The findings, published in The Journal of Prevention of Alzheimer's Disease, indicate that while future trials are needed, neurostimulation shows early promise as a treatment for Alzheimer's and other neurodegenerative disorders, such as Lewy body dementia.

The small trial tested the effectiveness of transcranial direct current stimulation (tDCS), which sends an  through electrodes affixed to the scalp to alter the functioning of targeted . The study was rigorously performed with results of two doses of tDCS compared with a control group. Unlike Alzheimer's medications that target plaques and protein tangles in the brain that disrupt , tDCS doesn't alter brain pathology. Instead, its purpose is restoring damaged neural pathways to improve cognitive functioning.

"Around one-third of the active treatment groups experienced clinically meaningful improvements in verbal learning in this pilot trial," said lead author Christian LoBue, Ph.D., Associate Professor of Psychiatry and Neurological Surgery at UT Southwestern and an Investigator in the Peter O'Donnell Jr. Brain Institute. "That's quite remarkable and mirrors the success rates for some of the earliest neuromodulation trials that led to Food and Drug Administration approval for treating depression. It's a very encouraging starting point."

Researchers focused on applying tDCS to patients' dorsal anterior cingulate cortex, an area in the  involved in the brain's memory network, to determine whether the device could improve learning and the consolidation of information stored in long-term memory.

Twenty-five patients with Alzheimer's disease from cognition specialty clinics in the Dallas-Fort Worth area took part in the study, receiving either neurostimulation for 20 minutes on 10 days during the two-week trial, or a sham treatment with no electrical current. Participants in the neurostimulation group received current levels that caused tingling, itching, or prickling sensations on their scalps. They took tests to measure memory and other high-level information processing skills before their first tDCS treatment and immediately after their last one.

One-third of the neurostimulated patients showed clinically meaningful improvement in verbal learning—their ability to recall a series of words soon after hearing them—versus none in the control group. For those who improved after receiving a lower current, effects persisted for eight weeks, pointing to the technique's promise as a potential treatment.

Additionally, 25% of patients who received neurostimulation at a lower current and 33% who received a higher current showed clinically meaningful improvements in their abilities to rapidly produce words, such as naming objects and actions. This compared with none in the  showing meaningful improvement.

Variations in cranial anatomy are normal, and Alzheimer's patients display differing patterns of brain atrophy. The research team said disparities in responses to tDCS could have resulted from underlying anatomical differences, and future trials could include brain imaging and customized placement of neurostimulation devices tailored to each individual's cranial anatomy. Dr. LoBue stressed that the findings are preliminary and will need further investigation.

"While we didn't see changes in their ability to form long-lasting memories in this trial, the area of the brain we've focused on could be a promising target for controlling a very debilitating set of Alzheimer's symptoms," Dr. LoBue noted. "We're at a critical starting point for understanding the possibilities."

More information: Christian LoBue et al, High definition transcranial direct current stimulation as an intervention for cognitive deficits in Alzheimer's dementia: A randomized controlled trial, The Journal of Prevention of Alzheimer's Disease (2025). DOI: 10.1016/j.tjpad.2024.100023


https://medicalxpress.com/news/2025-03-neurostimulation-potential-alzheimer-treatment-preliminary.html

Oral norovirus vaccine passes safety testing with strong immune response in older adults

 Researchers at Vaxart Inc. and the Center for Vaccine Development at the University of Maryland School of Medicine evaluated the safety and immunogenicity of an oral norovirus vaccine tablet, VXA-G1.1-NN. Results indicate that the vaccine was safe and well tolerated while eliciting robust systemic and mucosal immune responses in adults aged 55 to 80 years.

Norovirus infections cause approximately 20 million cases of acute gastroenteritis annually in the United States, leading to 70,000 hospitalizations and up to 800 deaths. The economic impact is estimated at $10.6 billion per year.

Older adults, particularly those in long-term care facilities, are disproportionately affected, with 90% of norovirus-associated deaths occurring in individuals aged 65 and older. No licensed vaccine currently exists to prevent norovirus infections, despite the significant health care burden it imposes.

In the study, "An Oral Norovirus Vaccine Tablet Was Safe and Elicited Mucosal Immunity in Older Adults in a Phase 1b Clinical Trial," published in Science Translational Medicine, researchers conducted a randomized, double-blind, placebo-controlled trial to assess the safety and immunogenicity of VXA-G1.1-NN in healthy .

A total of 65 participants aged 55 to 80 years were enrolled at three clinical sites in the United States. Participants were randomized to receive either the oral VXA-G1.1-NN vaccine or a placebo at a 2:1 ratio. The vaccine was administered at three dose levels (low, medium, and high) using a prime-boost strategy, with doses given 28 days apart.

Primary outcomes included safety and tolerability, measured by adverse events. Secondary outcomes assessed immunogenicity, including serum antibody responses, functional antibody activity, mucosal immunity, and cellular immune responses.

Vaccination with VXA-G1.1-NN was well tolerated across all dose levels. No serious adverse events or vaccine-related Grade 3 reactions were reported. Mild to moderate symptoms, including headache and malaise, were the most common side effects. Solicited adverse events were reported at lower rates in the high-dose group compared to lower doses.

Vaccination induced dose-dependent increases in VP1-specific serum immunoglobulin G (IgG) and immunoglobulin A (IgA) antibodies. Serum IgA and IgG responses remained elevated above baseline for 210 days. Functional antibodies, measured through a Norovirus Blocking Antibody Assay (NBAA), showed significant increases in the high-dose group, indicating neutralizing potential against the virus.

Robust mucosal immune responses were observed. Salivary and nasal IgA concentrations increased significantly by day 28 and remained elevated through day 210. Antibody-secreting cells expressing the gut-homing marker α4β7 were detected one week post-vaccination, supporting the vaccine's ability to induce a strong mucosal response.

Similar immune responses were observed between the current older adult participants (55 to 80 years) and younger adults (aged 18 to 49 years) from a prior clinical trial. A cross-study analysis showed comparable serum antibody titers, mucosal IgA levels, and antigen-specific B cell responses between the two age groups, suggesting that the vaccine's effectiveness was not significantly impacted by immunosenescence.

Oral administration of VXA-G1.1-NN was found to be safe, well tolerated, and capable of generating durable immune responses in older adults. The study supports the feasibility of an oral vaccine for norovirus, which could offer advantages over injectable vaccines, including ease of distribution and self-administration.

As a phase 1 safety trial, further trials are required to evaluate effectiveness of the vaccine. A phase 2 clinical trial is currently investigating a bivalent version targeting both GI.1 and GII.4 norovirus genogroups to explore potential cross-protection against diverse norovirus strains.

More information: Becca A. Flitter et al, An oral norovirus vaccine tablet was safe and elicited mucosal immunity in older adults in a phase 1b clinical trial, Science Translational Medicine (2025). DOI: 10.1126/scitranslmed.ads0556


https://medicalxpress.com/news/2025-03-oral-norovirus-vaccine-safety-strong.html