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Thursday, March 20, 2025

White House Hails Recent Drops In Egg And Gas Prices

 by Jack Phillips via The Epoch Times (emphasis ours),

The White House on March 17 announced a drop in egg and gasoline prices, calling it a win for the Trump administration’s economic agenda.

A woman shops for eggs at a store in New York City on Feb. 17, 2025. Samira Bouaou/The Epoch Times

Americans are continuing to see the benefits as the economic agenda of President Donald J. Trump and his administration comes into focus,” the White House press office said in a statement.

The average wholesale price per dozen of eggs has dropped to $3.10, down 47 percent from $6.55 per dozen from Jan. 21, 2025, the White House said.

Egg prices soared in recent months, reaching an average high of $4.95 per dozen in January, according to the Department of Labor. From January 2024 to January 2025, egg prices increased by 54 percent, data show.

A primary reason for the skyrocketing prices is avian influenza, which has led to the culling of tens of millions of egg-laying hens in recent months.

The U.S. Department of Agriculture (USDA) said last month that more than 23 million birds were culled in January to contain the virus, which followed the winnowing of more than 18 million in December 2024.

Several weeks ago, the USDA warned that egg prices could jump by more than 40 percent in 2025, with Agriculture Secretary Brooke Rollins noting that it would take some time before consumers would see an effect at the checkout counter.

It takes months for infected farms to dispose of the carcasses, sanitize their farms, and raise new birds, she said, while expressing optimism that the plan will help prices.

It’s going to take a while to get through, I think in the next month or two, but hopefully by summer,” Rollins said.

The USDA has enough staff to respond to bird flu despite the recent cuts to the federal workforce, Rollins said.

“Will we have the resources needed to address the plan I just laid out? We are convinced that we will,” she said, “as we realign and evaluate where USDA has been spending money, where our employees are spending their time.”

Aside from egg prices, the Trump administration on Monday said that gasoline prices have also dropped in recent weeks.

“The nationwide average for gas has declined for four straight weeks—down ten cents from one month ago and 42 cents from one year ago,” the statement said, pointing to data showing that the average for a gallon of gas is $2.99 or less at more than two-thirds of all stations.

The Trump administration has faced some blowback in recent days over its economic polices, particularly tariffs, and declines in the Dow Jones Industrial Average and Nasdaq.

When asked about the stock market index declines and tariffs, U.S. Treasury Secretary Scott Bessent said in an interview over the weekend that the markets are entering correction territory. He also said that the administration’s policies are designed to stave off a broader economic decline, but he did not rule out a recession.

“There’s no reason that it has to [go into a recession],“ he said in response to an NBC News moderator’s question. ”But I can tell you that if we’d kept on this track, what I could guarantee is we would have had a financial crisis. I’ve studied it. I’ve taught it.

“And if we had kept up at these spending levels, that everything was unsustainable. We are resetting and we are putting things on a sustainable path.”

https://www.zerohedge.com/political/white-house-hails-recent-drops-egg-and-gas-prices

Nvidia CEO Will Spend Hundreds Of Billions On US-Made Chips

 In an exclusive interview with the Financial Times, Nvidia's chief executive and co-founder, Jensen Huang, revealed that the company plans to spend several hundred billion dollars worth of U.S.-made chips and electronics over the next four years. Nvidia's move aligns with President Donald Trump's "America First" vision, shifting supply chains away from China and Taiwan and back to the US for national security purposes.

"Overall, we will procure, over the course of the next four years, probably half a trillion dollars worth of electronics in total," Huang said, adding, "And I think we can easily see ourselves manufacturing several hundred billion of it here in the US."

Huang said the latest artificial intelligence chips for Nvidia-powered servers can be manufactured at US-based factories operated by Taiwan Semiconductor Manufacturing Co. and Foxconn Technology Group.

This week, Nvidia hosted its annual GTC conference in California. Huang kicked off the event with a keynote address, unveiling new AI chips, upgrades, and all things AI. 

"Artificial intelligence has made extraordinary progress," Huang told the audience in a two-plus-hour keynote.

Onshoring efforts by Nvidia have already led to some graphics processing units being processed at TSMC's Arizona factory. 

Huang told FT that the Trump administration will supercharge AI in America: "Having the support of an administration who cares about the success of this industry and not allowing energy to be an obstacle is a phenomenal result for AI in the US." 

"The most important thing is to be prepared," said Huang, adding, "At this point, we know that we can manufacture in the US, we have a sufficiently diversified supply chain." He said if any disaster struck in Taiwan: "I would be uncomfortable, but it should be OK." 

This is because TSMC has committed $100 billion to build three chip foundries, an R&D center, and two packaging facilities in Arizona—building on a previous commitment of $65 billion on three chip foundries in the state, one of which is already operational. 

On Thursday, Taiwan's President, William Lai Ching-te, declared that TSMC's investment in Arizona is the "best model" for the island's efforts to establish supply chains that do not rely on China. In other words, the Arizona chip factories will help break the US free from China on chipmaking and secure critical supply chains domestically that meet the America First mandate. 

https://www.zerohedge.com/technology/nvidia-ceo-will-spend-hundreds-billions-us-made-chips

Yes, mRNA vaccine science should be deprioritized by the NIH for 5 reasons

 by Vinay Prasad

Recently, some are reporting that the NIH will work to deprioritize grants that seek to utilize mRNA vaccine technology in therapeutic applications. I think this is a wise decision for 5 reasons

  1. The brand is damaged. One of the points Jay Bhattacharya made in his confirmation hearing was about the use of medical products derived from aborted embryos. Jay said that there is a large group of Americans who will not accept these product which is a reason to reduce its funding. Whether we like it or not— acceptability among people is a factor in funding. Due to the disastrous Biden vaccine mandates and obfuscation around myocarditis and other safety signals, I fear the brand is damaged for most uses.

  2. There are alternatives. MRNA vaccines utilize the cell to create the protein against which immunogenicity is developed. There have been and there are alternative means to do this. In the case of the covid-19 pandemic, it was extremely convenient to use mRNA because by taking advantage of the cells intrinsic ability to create proteins we could go very quickly, which was at a premium because of lockdowns and closure (our bad policy). In other therapeutic arenas, that speed does not have the same salience.

  3. The long term safety profile is unknown. While this does not apply to uses in populations facing imminent death, it does apply to other infectious uses or in diseases with long survival. I tend to be skeptical of claims of unknown side effects until they are shown with validity. At the same time I know that the current safety program is extremely poor at characterizing safety signals. We do not yet know the long term impact of this technology, and again, if you have a terminal disease, the risks of long-term safety concerns are less important.

  4. Uses in cancer are of low pretest probability. With colleagues, we have a paper forth coming looking at the randomized control trials of cancer therapeutic vaccines. Spoiler alert: it is a sea of negative findings. What precisely is a cancer therapeutic vaccine? We take patients who have cancer, whose immune system maybe impaired or senescent, and we inject them with antigens against their tumor. Those antigens can be made with protein derivatives, or they can be given as an MRNA. But the idea is the same to sensitize the body against antigens in the body. These can— and have been— even been bespoke— made for each individual. All of these trials have failed. Provenge came to the US market but the trial has misuse of crossover, so the difference is likely due to docetaxel administration.

    From our paper (2015 above)

    The pretest probability for cancer therapeutic vaccines is lower than other domains of cancer biology, such as cytotoxic drugs, tyrosine kinase inhibitors, antibody drug conjugates and even cellular therapy. That is not to say that the pretest probability is zero. It never is, and something may succeed against the odds, but the role of funding is to try to improve one’s chances.

  5. If this class of product is so transformational and will be so well received by the American people then surely the companies that have already invested billions of dollars, and have hundreds of billions of dollars in cash would invest further in these products. But they are also very interested in these federal subsidies.

    Side note: Some cite these two papers to support mRNA vaccines

This is a phase 1 study without a control arm.

They took pancreas cancer patients with a single resectable panc lession. Did surgery. Had to have path R0 or R1 resection! Gave atezo, gave their bullshit vaccine, then gave FOLFIRNOX.

They present an analysis by biomarker plot in the paper.

No control arm. Some people destined to well already. Restricted to R0 or R1 resection (aka cherry picking) and the intervention was confounded with FOLFIRINOX.

A completely useless study.

Image

At least this is randomized

Problems. Volatile estimates, tons of censored patients, cherry picked 18 month time point.

If this melanoma vaccine is so good, what is it’s response rate in relapsed refractory metastatic disease?

I will bet it fails in large phase 3 without high drop out.

https://www.drvinayprasad.com/p/yes-mrna-vaccine-science-should-be

Jefferies Cuts Price Target on Phathom Pharmaceuticals to $13 From $17, Maintains Buy Rating

 On Wednesday, Jefferies analyst Glen Santangelo revised the price target for Phathom Pharmaceuticals (NASDAQ:PHAT) shares, reducing it to $13 from the previous $17, while continuing to recommend the stock as a Buy.

https://www.investing.com/news/analyst-ratings/jefferies-cuts-phathom-pharmaceuticals-target-to-13-93CH-3937661

Wednesday, March 19, 2025

Eli Lilly launches weight-loss drug Mounjaro in India after drug regulator approval

 Eli Lilly has launched its blockbuster diabetes and weight-loss drug Mounjaro in India following approval from country's drug regulator

https://www.marketscreener.com/quote/stock/ELI-LILLY-AND-COMPANY-13401/news/Eli-Lilly-launches-weight-loss-drug-Mounjaro-in-India-after-drug-regulator-approval-49382214/

Sanofi to acquire Dren Bio's immunology unit

 Sanofi on Thursday announced an agreement with biopharmaceutical company Dren Bio for the acquisition of its autoimmune disease treatment DR-0201.

The French healthcare group will acquire the Dren Bio affiliate Dren-0201 for an upfront payment of $600 million and potential future payments totalling $1.3 billion, it said in a statement.

The transaction is expected to close in the second quarter of 2025, it added.

https://ca.finance.yahoo.com/news/sanofi-acquire-dren-bios-immunology-062906602.html

Deportation Of Haitian Migrants Underway As Protection Status Revoked

 The first of what is expected to be many deportation flights has landed in the crisis worn country of Haiti this week, carrying 46 aliens including 25 convicted felons expelled from the US.  

The Trump Administration has revoked protections established during the Biden Administration that shielded roughly half a million Haitians from deportation.  They will lose their work permits and could be subject to removal from the country in the near term. Many of the Haitians deported Tuesday had crossed into the United States illegally or were waiting for Temporary Protected Status (TPS) approval, which grants individuals legal authority to remain in the country but does not offer a long-term pathway to citizenship

The administration has long way to go to rectify the damage done by Joe Biden and Democrats on cities like Springfield, OH, which was flooded with Haitians under federal relocation programs.  Around 30% of Springfield's population turned Haitian almost overnight; the situation became global news after Trump repeated claims made by locals that the third-world visitors were "eating people's dogs and cats" and other park wildlife.  The comment created a storm of online memes and even songs.

It should be noted that Haitian migrants are not even welcome in the Dominican Republic, the neighboring country to Haiti.  The D.R. is engaged in a constant battle to have Haitians removed en masse and the government considers the migrants to be harbingers of economic decay. 

Haitians in the US have reportedly sought to escape to sanctuary cities to avoid ICE arrest and deportation, but many are also considering leaving the country voluntarily. The majority of the 500,000 Haitians residing in the US under Biden TPS policies will likely be deported in the coming months regardless of sanctuary city laws.

US government intervention in third world affairs just isn't the answer.  Agencies like USAID have been exposed as completely incompetent (or corrupt) in their Haiti operations.  Only 2% of the $2.13 billion spent on Haitian aid actually ended up in Haitain hands.  The rest has disappeared into the pockets of various NGOs.  American taxpayers have not only been expected to shell out billions for such countries, they are also expected to tolerate mass cultural invasion when the money doesn't get to where it was supposed to go.

The planes taking migrants back to their point of origin are a welcome sight for the majority of American voters who picked Trump at the ballot box specifically to enact unyielding immigration reform.   

https://www.zerohedge.com/geopolitical/deportation-haitian-migrants-underway-protection-status-revoked