Kazia Therapeutics (KZIA +0.9%) has collaborated with Dana-Farber Cancer Institute (DFCI), to investigate its lead drug, paxalisib (formerly GDC-0084), in primary central nervous system (PCNSL) lymphoma, a potential new indication for the drug.
DFCI will initiate an open-label Phase 2 trial of paxalisib in PCNSL, and expects to recruit up to 25 patients, taking up to 2 years to complete. This trial will be sixth ongoing trial of paxalisib in brain cancer.
Kazia will provide support including study drug and a financial grant.
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