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Thursday, January 23, 2020

GE medical equipment gets FDA cybersecurity warning

The Food and Drug Administration issues a warning to healthcare providers and facilities over cybersecurity vulnerabilities in certain electronic health care data equipment made by General Electric (NYSE:GE) that may introduce risks to patients while being monitored.
The flaw affects some GE Healthcare Clinical Information Central Stations and Telemetry Servers, which are used mostly for monitoring patient data such as temperature, heartbeat, blood pressure and patient status, typically from a central location in a facility such as a nurse’s workstation.
The vulnerabilities could “allow an attacker to remotely take control of the medical device and to silence alarms, generate false alarms and interfere with alarms of patient monitors connected to these devices,” the FDA says.
https://seekingalpha.com/news/3534213-ge-medical-equipment-gets-fda-cybersecurity-warning

For low back pain in older adults, treatment doesn’t match guidelines

Many Medicare patients with new episodes of low back pain receive care inconsistent with current guidelines – including high use of opioids and advanced imaging tests, reports a study in the February issue of Medical Care. The journal is published in the Lippincott portfolio by Wolters Kluwer.
Opioids are prescribed to nearly one-third of older adults with “new and persistent” Low Back pain – in most cases without trying guideline-recommended pain medications or physical therapy, according to the new research by Dan Pham Ly, MD, MPP, of Harvard University. He comments, “This study raises concerns about excessive use of low-value and potentially harmful treatments for the common problem of LBP in older adults, with under-use of evidence-based, guideline-recommended treatments.”
Many Medicare Patients Don’t Receive Evidence-Based Treatments for New LBP
The study used Medicare claims data on more than 162,000 older adults with new LBP from 2011 through 2014. About 70 percent of patients were women; average age was approximately 77. None had received previous opioid treatment. The analysis included information on multiple visits for LBP over the course of a year, providing data on the timing and sequence of care.
Over half of patients (54 percent) made only one healthcare visit for LBP. That’s consistent with evidence that many new episodes of LBP are self-limiting. As stated in the current American College of Physicians guidelines, most patients with LBP “improve over time regardless of treatment.”
Advanced imaging studies – computed tomography (CT) or magnetic resonance imaging (MRI) scans – were used in about 15 percent of patients overall, and 29 percent of those with two or more LBP visits. In about half of cases, CT or MRI scans were performed within six weeks. That’s contrary to an American Academy of Family Physicians statement that most patients don’t need advanced imaging studies for initial evaluation of LBP.
Opioids were prescribed to about one-fourth of patients overall, including one-third of those with two or more LBP visits. In contrast, LBP guidelines suggest that other pain relievers – including nonsteroidal anti-inflammatory drugs (NSAIDs), such as naproxen or ibuprofen – should be tried before opioids.
Physical therapy was prescribed to only 11 percent of patients overall and 17 percent of those with two or more visits. Evidence suggests that early use of physical therapy can avoid the use of opioids in patients with LBP.
Most patients treated with opioids had not received a prescription NSAID or physical therapy. Chronic opioid use developed in about one percent of patients overall, and nearly two percent of those with two or more visits.
Low back pain is a common reason for healthcare visits – in a given year, about ten percent of people will develop a new episode of LBP. Studies examining trends in LBP treatment found increasing use of opioids, and decreased use of NSAIDs, up to 2010. The new analysis focused on more recent patterns in evaluation and treatment of LBP in Medicaid patients, including data on repeated visits over one year.
“Many patients who develop new LBP receive guideline non-concordant care such as early advanced imaging and opioids before other modalities like PT and prescription NSAIDs,” Dr. Ly writes. At least in the first half of the past decade, one-third of patients making two or more LBP visits received opioids – often without having tried other recommended treatments.
Dr. Ly calls for future studies examining barriers to guideline-recommended treatments for LBP in older adults – particularly physical therapy and NSAIDS. He also points out that pain management can be challenging in older adults, highlighting the need for studies to compare the safety and effectiveness of medication options.
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Click here to read “Evaluation and Treatment Patterns of New Low Back Pain Episodes for Elderly Adults in the United States, 2011-2014.”
DOI: 10.1097/MLR.0000000000001244
https://www.eurekalert.org/pub_releases/2020-01/wkh-flb012320.php

Texas Officials Investigating Suspected Case of Coronavirus

Officials in Texas are investigating a suspected case of 2019 Novel Coronavirus, the virus that’s hit China and spread to multiple other countries.
The patient is a student at Texas A&M. The male patient traveled from Wuhan, the city at the epicenter of the outbreak, within the past 14 days.
“Health care providers were aware of public health guidance on novel coronavirus and quickly recognized that the patient met the criteria for coronavirus testing and is being kept isolated at home, while the precautionary testing is done,” the Brazos County Health Department said in a statement.
“If there is a confirmed case, we will promptly announce it.”
At a press conference Thursday afternoon, Dr. Eric Wilke of the department said that the patient is “self-isolated.” Asked if the student lives on campus, the official declined to answer. The student likely attended classes before being isolated. It was not clear how many people he’d been in contact with.
The patient “is doing well” and “was doing well last night,” he added. Health officials consider the patient, who is between 20 and 30 years old, low risk.
The department urged people who traveled to Wuhan to call authorities or seek medical care if they develop flu-like symptoms like fever, coughing, shortness of breath, and a sore throat.
People should call their healthcare provider before traveling to get medical care, the district said.
Brazos County, which has a population of around 225,000, sits south of Dallas between Austin and Houston in southeast Texas.
The first confirmed case of the 2019 Novel Coronavirus was confirmed this week in Washington State, federal officials said. The patient recently returned from Wuhan and sought treatment at a medical facility.
Epoch Times Photo
A Chinese man wears a protective mask and glasses before boarding a train at a railway station in Beijing, China on Jan. 23, 2020. (Kevin Frayer/Getty Images)
“While originally thought to be spreading from animal-to-person, there are growing indications that limited person-to-person spread is happening. It’s unclear how easily this virus is spreading between people,” the Centers for Disease Control and Prevention (CDC) said in a statement about the first confirmed case.
A person who flew into Los Angeles on Wednesday and displayed symptoms of an illness potentially resembling coronavirus and was sent a hospital for precautionary testing Thursday.
Later on Thursday, U.S. authorities told people to avoid traveling to Wuhan.
“There is an ongoing outbreak of respiratory illness caused by a novel (new) coronavirus that can be spread from person to person,” the CDC said in a travel notice.
“Chinese officials have closed transport within and out of Wuhan, including buses, subways, trains, and the international airport. Preliminary information suggests that older adults and people with underlying health conditions may be at increased risk for severe disease from this virus.”
The agency did not say to avoid nonessential travel to other parts of China.
The World Health Organization (WHO) said at a press conference Thursday that the coronavirus is not yet a global health emergency, though it is one inside of China.
“Make no mistake. This is an emergency in China, but it has not yet become a global health emergency,” said Dr. Tedros Adhanom Ghebreyesus, the head of WHO, at the press conference.
“I am not declaring a public health emergency of international concern today,” he added.
Eighteen people have died from the coronavirus, all inside of China. Hundreds of others have been infected, with cases cropping up in Japan, South Korea, Thailand, Singapore, Vietnam, Hong Kong, and Taiwan, in addition to the United States and China.
https://www.theepochtimes.com/texas-officials-investigating-suspected-case-of-coronavirus_3214031.html

Bayer nearing Roundup settlement – report

Bayer (OTCPK:BAYRY +4%) shares rallied into the close on headlines that the company is in talks to settle cancer cases involving its Roundup weedkiller for $10B.
Mediator Ken Feinberg said last week that he was “cautiously optimistic that a settlement will ultimately be reached.”
More to come…
https://seekingalpha.com/news/3534130-bayer-nearing-roundup-settlement-report

EHealth up 11% after hours on expected bullish Q4 results

On a preliminary basis, eHealth (NASDAQ:EHTH) expects the following results for Q4:
Revenue: $$257.5M – 259.5M versus consensus of $194.9M. Medicare segment: $239.0M – 240.5M.
Net income: $53.0M – 55.0M.
Non-GAAP EBITDA: $98.5M – 100.5M.
Medicare membership up 88%. Medicare Advantage membership up 100%.
Major medical individual and family plan membership up 1%.
2019: Revenue: $462.0M – 464.0M from $365.0M – 385.0M. Medicare segment: $403.5M – 405.0M from $318.0M – 333.0M.
Net income: $31.0M – 33.0M from $20.9M – 25.9M; non-GAAP EBITDA: $89.0M – 91.0M from $65.0M – 70.0M.
Major medical individual and family plan membership down 25%.
Shares up 11% after hours.
https://seekingalpha.com/news/3534152-ehealth-up-11-after-hours-on-expected-bullish-q4-results

Emirates NBD Plans to Sell Up to 1.04% Stake in NMC Health

Emirates NBD PJSC (EMIRATES.DFM) said Thursday that it plans to sell up to 2.2 million shares in FTSE 100-listed NMC Health PLC, or a 1.04% stake in the company, via an accelerated bookbuild.
The Dubai-based bank said the final number of shares to be placed and the price will be agreed at the close of the bookbuild process, which will be launched immediately.
https://www.marketscreener.com/NMC-HEALTH-PLC-10352304/news/Emirates-NBD-Plans-to-Sell-Up-to-1-04-Stake-in-NMC-Health-29881962/

PureTech Health Cuts Karuna Therapeutics Stake to 20.4%

PureTech Health PLC said Thursday that it has cut its stake in Boston-based Karuna Therapeutics to 20.4%, raising $200 million in cash.
PureTech, a Boston-based, London-listed biotechnology company, said it sold 2.1 million Karuna shares to Goldman Sachs Group, after which it continues to hold 5.3 million shares in the Nasdaq-listed company. PureTech continues to have a right to royalty payments on net sales of any commercialized product covered by a license granted to Karuna, it said.
PureTech said the sale provides it with additional cash to fund its growth.

https://www.marketscreener.com/PURETECH-HEALTH-PLC-22619613/news/PureTech-Health-Cuts-Karuna-Therapeutics-Stake-to-20-4-29879222/