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Thursday, October 29, 2026

Bristol Myers beats, raises 2026 EPS guidance to $6.35–$6.55 as Eliquis and new launches drive

 

Bristol Myers beats Q3 2026 estimates and raises 2026 EPS guidance to $6.35–$6.55 as Eliquis and new launches drive growth

  • Q3 2026 non-GAAP EPS was $1.35, down 17% year over year, beating consensus estimates.
  • Q3 2026 revenue was $13.1B, up 7% year over year, beating expectations; growth portfolio increased 12%.
  • Raised 2026 non-GAAP EPS guidance to $6.35–$6.55; full-year revenue guidance not disclosed.
  • Company issued 2026 revenue guidance of $49.75–$50.25B alongside updated EPS outlook.
  • Eliquis grew 26% to $4.7B, with Europe loss-of-exclusivity expected to begin impacting results in Q4.
  • Key growth brands Reblozyl, Breyanzi, Camzyos and Qvantig delivered strong revenue increases ranging from 22% to 48%.
  • Pipeline de-risking highlighted Zenbexus approval, Admiperant positive data in IPF and Raise101 GepNET radiopharmaceutical success.
  • Admiperant 120mg dose missed statistical significance, raising questions ahead of the larger PPF outcome readout.
  • Gross margin was 68.4%, pressured by product mix and a one-time contract termination expense.
  • Autoimmune CAR-T zolacel program was voluntarily paused; root cause addressed and regulators engaged to restart clinical trials.
  • Management tone remained confident, citing diversified growth drivers, productivity savings and a robust late-stage pipeline cadence.
  • Investors focused on Milvexian stroke and AF data, Admiperant upside, business development deployment and AI opportunities.
  • Main concern is durability of post-LOE growth as Eliquis patents expire and pivotal pipeline readouts carry execution risk.
  • Quarter characterized as strong, driven by Eliquis outperformance, broad-based growth portfolio strength and multiple positive late-stage pipeline readouts.

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