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Thursday, February 26, 2026

Bristol, SystImmune Phase III izalontamab brengitecan trial in metastatic TNBC meets dual primary endpoints

 


  • Interim topline data showed statistically significant, clinically meaningful progression-free and overall survival improvements versus chemotherapy.
  • Study evaluated antibody-drug conjugate izalontamab brengitecan in patients with previously treated metastatic triple-negative breast cancer.
  • Izalontamab brengitecan is jointly developed by Bristol Myers Squibb and SystImmune as an antibody-drug conjugate therapy.
  • RBC Capital initiated Bristol-Myers Squibb at Sector Perform with a $60 price target, citing depth of the late-stage pipeline.

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