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Wednesday, February 25, 2026

Soleno beats Q4 ests with non-GAAP EPS $0.80 (+163% YoY), revenue $91.7M on rapid VYKAT XR launch

 

Soleno Therapeutics beats Q4 estimates with non-GAAP EPS $0.80 (+163% YoY) and revenue $91.7M on rapid VYKAT XR launch

  • Q4 2025 revenue grew ~40% sequentially, reflecting strong ongoing momentum from the VYKAT XR launch.
  • FY 2025 net income was $20.9M as Soleno achieved full-year profitability within nine months of first sales.
  • VYKAT XR has penetrated ~12.5% of the U.S. addressable PWS market, with patient adherence described as high.

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