Incyte posts Q4 revenue of $1.51B topping estimates while adjusted EPS of $1.80 misses, with total revenue up 28% in Q4 and 21% for FY2025, and guides 2026 net product revenue to $4.77–$4.94B; on its call, it said Jakafi XR is expected to be approved and launch in mid‑2026 and that its 2026 outlook assumes no incremental XR revenue.
2025 revenue grew 21% to $5.4B; product sales up 20%, above guidance and expectations.
Jakafi 2025 sales rose 11% to $3.09B; 2026 growth slows to mid‑single digits pre‑LOE.
Core business ex‑Jakafi grew 53% to $1.26B; guided to ~30% growth in 2026.
Opsilura sales up 33% to ~$678M; 2026 guide implies ~15% growth amid pricing for access.
2026 total revenue guided to $4.77–$4.94B, +10–13% YoY, despite lower milestone revenue.
Late‑stage pipeline expanded to 14 pivotal trials by year‑end 2026 across 7 key assets.
Povorcitinib for HS filed in US/EU; positioned as first oral HS option, targeting pre‑biologic use.
Operating expense growth held to ~4% in 2026, driving continued operating leverage.
Key risk: execution on multiple Phase III trials and launches to replace Jakafi post‑2028.
Strong quarter, driven by broad‑based product growth and outsized expansion of the ex‑Jakafi portfolio. Main concern: flawless execution on a crowded 2026–2028 launch and pivotal trial slate to offset eventual Jakafi loss of exclusivity.
Quest Diagnostics reports Q4 and full-year 2025 results with strong organic growth and margin expansion despite investments, raises its 2026 outlook, hikes the quarterly dividend 7.5% to $0.86, and expands its share repurchase authorization by $1B.
Double‑digit full‑year EPS and revenue growth driven by strong organic volumes and advanced diagnostics.
Corewell Co‑Lab to add ~$250M revenue in 2026 at low single‑digit margins, ramping to low‑teens in 2027.
Project Nova to dilute 2026 EPS by ~$0.25, partly offset by Invigorate 3% cost‑savings program.
PAMA cuts delayed again to end of 2026; company pushing RESULTS Act for structural reform.
Cash from operations fell in 2026 guidance due to loss of ~$270M prior‑year and payroll one‑time benefits.
Management tone confident; emphasizes share gains, stable pricing, and sustained high‑single‑digit organic growth.
Strong quarter, driven by broad‑based organic growth, high‑margin consumer testing, and advanced diagnostics. Main concern: near‑term margin drag from low‑margin Corewell ramp, Project Nova spend, and dialysis mix even as cash flow normalizes lower from 2025 one‑time benefits.
CVS Health Corp (CVS,Financial)unsettledinvestors after management chose to reiterate its 2026 profit outlook, a decision that came despite a stronger-than-expected fourth quarter. The company said it continues to expect adjusted earnings of $7 to $7.20 a share in 2026, with the midpoint landing below the average analyst estimate. That restraint weighed on early trading, with shares falling as much as 3.7% at the New York open before recovering some ground, as the guidance did not move meaningfully above what the market had already priced in.
Analysts at Leerink Partners and TD Cowen characterized the update as underwhelming but pointed to a deliberate tone from management as conditions across the insurance industry remain unsettled. Other insurers have struggled to forecast medical costs, and that uncertainty has begun to show up in longer-term outlooks. UnitedHealth Group Inc. recently projected declining revenue in 2026 for the first time in more than three decades, underscoring how volatile the environment has become. CVS also continues to face scrutiny from lawmakers and regulators in Washington, with US President Donald Trump calling on insurers to lower prices, adding another layer of pressure to an already complex operating backdrop.
Within that context, CVS is signaling incremental progress rather than acceleration. At an investor day in December, the company said all three of its segments — insurance, pharmacy, and drug-benefit management — are expected to expand in 2026, marking a notable shift for its retail drugstores, where profitability had previously been expected to shrink. Medicare Advantage enrollment declined slightly for 2026, in line with expectations, while management said margins in the Medicare business should increase. CVS also trimmed its operating cash flow outlook to at least $9 billion, down from a prior estimate of at least $10 billion, citing the timing of certain payments. The guidance update followed a fourth quarter in which adjusted earnings reached $1.09 per share and revenue climbed to $105.7 billion, both exceeding average analyst estimates, suggesting near-term execution remains intact even as longer-term visibility remains constrained.
Dozens of families are illegally living in dilapidated trailers in the shadow of Citi Field — draining off water from fire hydrants and swiping electricity while running black-market auto repair shops.
The unsightly, gypsy-like encampment under the Whitestone Expressway, populated largely by Spanish-speaking migrants, has become a nightmare for residents and merchants along a stretch of Queens near the New York Mets’ home field — yet the city has done nothing, locals told The Post.
Dozens of families live under the Whitestone Expressway and run black-market auto repair shops and car washes.James Messerschmidt for the NY Post
“We gave up calling the police,” Luke Huwang, manager of Empire State Autobody on Northern Boulevard, told The Post on Monday. “The police don’t touch them. The police will take their customers’ cars and impound them, but they leave the motorhomes and all these people here.
“They drink a lot,” Huwang said of the illicit street dwellers.
“And they do the barbecue when the Mets play. They pull the electricity from the light poles and from above, you know, the underside of the roadway.”
Neighborhood regulars said the intruders tap into fire hydrants to bathe and run illegal car washes, auto body and auto repair shops — mostly overnight to avoid harassment from the NYPD.
They live in nearly two dozen rundown RVs, motor homes and campers between 126th Street and 127th Place along Northern Boulevard — with only one of the vehicles seen with a legal license plate.
Some occupants of the illegal encampment were initially displaced by Queens’ new $780 million soccer stadium.James Messerschmidt for the NY Post
“The whole area is bad,” said a man who claimed he lived in an RV in Marina Park for eight months. “Real dangerous. Especially at night, real dangerous. Who the f–k is calling the cops?
“They settle things with machetes around here,” he said. “It’s more than a year. It’s not quite two years yet, but it’s more than a year since it started here.”
Residents of the unsightly community declined to comment to The Post, most of them claiming they did not speak English as they roamed the area and slipped into a local liquor store.
Neighbors said the encampment grew out of a row of auto shops and apartments that were displaced by the development of the new $780 million soccer stadium next to Citi Field — with some taking the money from their buyout to move to the Bronx, but others moving under the expressway overpass.
“The whole area is bad,” said a man who claimed he lived in an RV in Marina Park for eight months.James Messerschmidt for the NY Post
The new field, set to open next year, will be the new home of New York City FC soccer team.
At first there were about 10 campers, but the number grew to nearly 100 over the past year, locals said.
Cops have raided the black-market shops and towed away their customers’ vehicles, but the savvy illegal business owners now simply wait until night to open for business, operating without police scrutiny.
Only one of the 23 campers and RVs spotted by The Post had a legal license plate.James Messerschmidt for the NY Post
“They started living here full-time little over a year ago,” said Brian Jung, who owns Ryan Auto Inc., a legal shop, on Northern Boulevard. “You can see here they’re opening up the base of the electrical poles and they’re running wires over to do their work and to live in those motor homes.
“In the summertime, yeah, they do they open up all the fire hydrants,” Jung said.
“They open them up, and they just leave them all open, and they take showers. Yeah, it’s kind of wild. It’s been growing but I don’t know how many more they could fit. I guess they could squeeze in a few more.”
The NYPD did not respond to a Post request for comment.
