Search This Blog

Friday, January 31, 2020

ResMed buys CPAP resupply software developer

ResMed (RMD -3.1%) subsidiary Brightree has agreed to acquire privately held SnapWorx, LLC, for an undisclosed sum.
The Brentwood, TN-based SaaS provider is focused on the continuous positive airway pressure (CPAP) resupply market.
https://seekingalpha.com/news/3536954-resmed-buys-cpap-resupply-software-developer

Profound Medical gets 2020 “Best Pick” honors from Raymond James

Profound Medical Corp (Profound Medical Corp Stock Quote, Chart, News TSX:PRN) takes top honors from Raymond James analyst Rahul Sarugaser who in a Monday update to clients upped his rating from “Outperform 2” to “Strong Buy” while raising his price target from $35.00 to $45.00 for PRN.
Toronto-based Profound Medical’s TULSA-PRO technology, which is designed for the ablation of prostate tissue, combines real-time MRI with transurethral robotically-driven therapeutic ultrasound and closed-loop thermal feedback control. Last fall, the TULSA-PRO was given 510(k) marketing authorization in the US and Profound has started its marketing of the product.
On Monday, Profound announced the closing of its previously-announced equity offering of 3.4 million shares at $15.14 per share for net proceeds of C48.3 million. The injection puts PRN’s cash position at roughly $71.6 million, says Sarugaser, enough to call it the company’s last equity raise needed to fully commercialize the TULSA-PRO.
Sarugaser likes Profound’s move from a capital equipment sales model to a pure-play recurring revenue model, where the company will charge a pay-per-use fee with no installation costs. The analyst figures the model will reach a steady state COGS margin of 30 per cent by 2023, with Sarugaser projecting installations of ten, 22 and 38 units in years 2020, 2021 and 2022, respectively.
“These units, we estimate, will have average utilization rates increasing from 74, to 90, to 106 annual patients per device during those same years, driving revenues of $11.1 million, $27.2 million, and $63.4 million, respectively. Given that we anticipate PRN generating $5.4 million in 2019FY, we recognize that $11.1 million in 2020 appears relatively modest. These light 2020 revenues we see as a function of PRN substituting short-term capital equipment revenue with massive, long-term recurring revenue. We view this as a deft strategy enacted by PRN’s veteran management,” Sarugaser wrote.
The analyst warns that while PRN’s share price could have less upside over the shorter term, for investors looking at the long-term Profound “represents an extremely attractive investment proposition” and thus gets Sarugaser’s “2020 Best Pick” status.
In particular, Saruagser has high praise for Profound’s management, saying
“We remind you that PRN’s CEO, Dr. Arun Menawat, and CFO, Mr. Aaron Davidson, previously worked together at Novadaq technologies, growing the company from a small, Toronto-based start-up to a billion dollar Nasdaq-listed company, which was eventually sold to Stryker for 20x sales (US $700 million). This seasoned management team, indeed, has been there, done that. We have deep confidence in management’s capacity to execute the deft plan they have set out for PRN. For all these reasons, we have selected PRN as our 2020 Best Pick,” Sarugaser says.
The analyst sees PRN registering $11 million in revenue in fiscal 2020 and an EBITDA loss of $23 million. At the time of publication, his new $45.00 target represented a projected 12-month return of 182 per cent. PRN finished 2019 up 168 per cent for the year.
Profound Medical gets 2020 “Best Pick” honours from Raymond James

Lilly launches migraine med Reyvow

Eli Lilly (LLY -1.7%) announces that Reyvow (lasmiditan) C-V 50 mg and 100 mg tablets, indicated for the acute treatment of migraine with or without aura, is now available for prescription and will be available in U.S. pharmacies in the next several days.
Lasmiditan is an orally available 5-HT1F receptor agonist that blocks pain transmission without the side effects of the class of migraine therapies called triptans. The 5-HT1F receptor is a serotonin subtype that lacks the vasoconstrictive properties of other serotonin receptors which can cause adverse cardiac events in patients with cardiovascular or cerebrovascular disease.
The FDA approved the medicine in October 2019. The time lag before launch was due to a DEA review of the drug’s classification.
https://seekingalpha.com/news/3536929-lilly-launches-migraine-med-reyvow

Analyst action, Jan. 31

AdaptHealth (NASDAQ:AHCO) initiated with Buy rating and $17 (31% upside) price target at Stifel.
DURECT (NASDAQ:DRRX) initiated with Buy rating and $5 (158% upside) price target at B. Riley FBR. Shares up 6% premarket.
InMed Pharmaceuticals (IN CN) initiated with Buy rating and C$1.50 (341% upside) price target at Maxim Group (OTCQX:IMLFF).
Neptune Wellness Solutions (NEPT CN) initiated with Market Perform rating and C$3.75 (14% upside) (NASDAQ:NEPT).
Phreesia (NYSE:PHR) initiated with Overweight rating and $36 (15% upside) price target at KeyBanc.
Arena Pharmaceuticals (NASDAQ:ARNA) upgraded to Overweight with a $58 (32% upside) price target at JPMorgan. Shares up 2% premarket.
United Therapeutics (NASDAQ:UTHR) upgraded to Overweight with a $120 (25% upside) price target at JPMorgan.
Amgen (NASDAQ:AMGN) downgraded to Underperform with a $185 (18% downside risk) price target at Baird on soft 2020 guidance. Shares down 3% premarket.
Global Blood Therapeutics (NASDAQ:GBT) downgraded to Hold with a $75 (10% upside) price target at SunTrust Robinson Humphrey.
Intra-Cellular Therapies (NASDAQ:ITCI) downgraded to Neutral with a $26 (13% upside) price target at JPMorgan. Shares down 9% premarket.
ResMed (NYSE:RMD) downgraded to Neutral at UBS after FQ2 results.
Rubius Therapeutics (NASDAQ:RUBY) downgraded to Neutral with a $9 (17% upside) price target at JPMorgan. Shares down 5% premarket.
https://seekingalpha.com/news/3536846-baird-downgrades-amgen-on-soft-guidance-in-premarket-analyst-action

Merck withdraws Keytruda application in Europe for esophageal cancer

Merck (NYSE:MRK) has withdrawn its marketing application in Europe seeking approval to use Keytruda (pembrolizumab) to treat cancer of the esophagus. The EMA determined that the data supporting the application were not sufficient to prove that treatment prolonged survival.
https://seekingalpha.com/news/3536882-merck-withdraws-keytruda-application-in-europe-for-esophageal-cancer

EMA accepts Seattle Genetics’ tucatinib application for HER2+ breast cancer

The European Medicines Agency (EMA) has accepted for review Seattle Genetics’ (SGEN +0.4%) marketing application seeking approval for tyrosine kinase inhibitor tucatinib, combined with HER2/neu receptor antagonist trastuzumab and chemo agent capecitabine, for adult patients with locally advanced unresectable or metastatic HER2-positive breast cancer, including those with brain metastases, who have received at least two prior lines of anti-HER2 therapy.
The company filed its application in the U.S. a month ago under the FDA’s Real-Time Oncology Review Pilot Program.
https://seekingalpha.com/news/3536908-ema-accepts-seattle-genetics-tucatinib-application-for-her2-breast-cancer

Reata Pharma up 11% on potential acquisition interest

Reata Pharmaceuticals (RETA +10.9%) is up out the gate on reports that Amgen (AMGN -3.9%) is mulling acquiring assets in the space.
Reata’s lead candidate is bardoxolone methyl, in late-stage development for a kidney disorder called Alport syndrome, connective tissue disease-pulmonary arterial hypertension and focal segmental glomerulosclerosis.
Another late-stage candidate is omaveloxolone for a degenerative neuromuscular disorder called Friedreich’s ataxia.
https://seekingalpha.com/news/3536894-reata-pharma-up-11-on-potential-acquisition-interest