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Tuesday, June 10, 2025

LA anti-ICE looters shatter Apple store and make off with iPhones, Adidas

 Looters tore apart stores across Los Angeles as daytime protests against ICE-immigration raids descended into chaos overnight, yet again — and even a museum dedicated to Japanese-American immigrants was vandalized.

Windows were smashed and merchandise was stolen at LA’s Broadway Apple store Monday night, while down the block the Adidas store was broken into and robbed of sneakers by frenzied crowds.

The windows of a nearby jewelry store were also smashed open and the shop’s shelves were completely emptied by looters, while two marijuana dispensaries and a pharmacy were also raided, according to NBC 4.

A worker boards up an Adidas store after it was looted following days of protests against federal immigration sweeps and the deployment of the California National Guard and U.S. Marines, in downtown Los Angeles, California, U.S., June 10, 2025.REUTERS
Wooden boards covered the windows and doors of a T-Mobile store that was looted during a protest in downtown Los Angeles on June 9, 2025.Ringo Chiu

Footage from the chaos showed mobs masked and hooded hooligans pouring into the stores and grabbing armloads of whatever was in sight and then pouring back out onto the street spilling goods as they fled.

Some ran right into the ranks of waiting cops, but many were able to muscle themselves free from the overwhelmed officers and escape.

“This is so ridiculous. This doesn’t look like they’re protesting for ICE or anything. Just looting the stores,” one fed up business owner who watched the overnight chaos unfold told News Nation.

Across town in Little Tokyo, a sushi restaurant — Otoro Sushi — even had its doors ripped open by mobs, with troublemakers appearing to make off with a computer monitor and other equipment while onlookers yelled that they were “Making us look bad.”

Broken glass lies on the floor after stores were looted following days of protests against federal immigration sweeps and the deployment of the California National Guard and U.S. Marines, in downtown Los Angeles, California, U.S., June 10, 2025.REUTERS
Products lie scattered in an Apple store after it was looted following days of protests against federal immigration sweeps and the deployment of the California National Guard and U.S. Marines, in downtown Los Angeles, California, U.S., June 10, 2025.REUTERS
People clean graffiti after days of protests against federal immigration sweeps and the deployment of the California National Guard and US Marines, outside the Japanese American National Museum in Little Tokyo, Los Angeles, California, U.S., June 10, 2025.REUTERS

The Japanese American National Museum was even targeted, with “F**k ICE” and other graffiti spray-painted across windows, walls, and even over what appeared to be an outdoor exhibit about Japanese-American soldiers who fought in WWII as their families were locked away in internment camps.

Volunteers flocked to the museum Tuesday morning with brushes and soap to help scrub away what vandalism they could, photos showed.

And back on Broadway workers were seen laboring to sweep up and take stock of the damaged stores, while shattered windows and doors were boarded up.

Adidas bags lie on the floor after stores were looted following days of protests against federal immigration sweeps and the deployment of the California National Guard and U.S. Marines, in downtown Los Angeles, California, U.S., June 10, 2025.REUTERS
Broken glass lies on the floor of a cannabis stores after it was looted following days of protests against federal immigration sweeps and the deployment of the California National Guard and U.S. Marines, in downtown Los Angeles, California, U.S., June 10, 2025.REUTERS
Broken pill bottles and police tape lie on the ground outside a CVS pharmacy after it was looted following days of protests against federal immigration sweeps and the deployment of the California National Guard and U.S. Marines, in downtown Los Angeles, California, U.S., June 10, 2025.REUTERS

At least 14 people were arrested for looting, according to police, while another 96 were arrested for failure to disperse.

The protests were expected to continue for a fifth day and night Tuesday, as President Trump dispatched another round of National Guard troops — as well as Marines forces — to quell the chaos.

Those deployments — which California’s and LA’s Democrat leaders say have done nothing but fuel the chaos in the city — is expected to cost at least $134 million, the Pentagon revealed Tuesday.

Defense Secretary Pete Hegseth said its likely the troops will remain in LA for about 60 days, telling a House budget hearing that the protestors were “rioters, looters and thugs.”

Chaos was sparked in the City of Angels Friday after ICE carried out numerous raids to arrest suspected illegal immigrants. Activists attempted to block the raids and later picketed a downtown detention center where some of the detainees were being held, before the demonstrations snowballed into all-out riots in some areas.

https://nypost.com/2025/06/10/us-news/la-anti-ice-looters-shatter-apple-store-and-make-off-with-iphones-adidas-in-another-night-of-chaos/

US, Mexico Near Deal to Cut Steel Duties and Cap Imports

 The US and Mexico are closing in on a deal that would remove President Donald Trump’s 50% tariffs on steel imports up to a certain volume, according to people familiar with the matter, a revamp of a similar deal between the trade partners during his first term.

Trump hasn’t been directly involved in the negotiations and would need to sign off on any deal. The talks are being led by Commerce Secretary Howard Lutnick, according to the people, who asked not to be identified as the discussions are private.

The people said the agreement hasn’t been finalized. Under its current terms, it would allow US buyers to import Mexican steel duty-free as long as they kept total shipments below a level based on historical trade volumes, according to the people. The new cap would be higher than what was allowed under a similar deal during Trump’s first term, they said, which was never a fixed figure but designed to “prevent surges.”

The White House didn’t immediately respond to a request for comment. Mexican President Claudia Sheinbaum’s office also didn’t respond to a request for comment.

US steel stocks moved lower in late trading after Bloomberg’s report. Cleveland-Cliffs Inc. dropped more than 7%, and Nucor Corp. fell more than 4%. The Mexican peso trimmed losses.

At an event on Tuesday, Mexican Economy Minister Marcelo Ebrard said he told US officials in meetings last week that steel tariffs are not justified in Mexico’s case because the US sends more steel to Mexico than vice versa. Last Friday, he posted a picture that showed him shaking hands with a smiling Lutnick in Washington.

“We are waiting for their response, because on Friday we gave them the details of Mexico’s argument and we are right,” Ebrard told reporters Tuesday. “So we are going to wait for their response which will probably be this very week.”

Trump last week announced he would double steel duties to 50% after saying he would approve the purchase of United States Steel Corp. by Japan’s Nippon Steel Corp., a move he said would protect the domestic industry and national security. While domestic steelmakers welcome the move, end-users have urged the administration to ease the tariffs.

https://finance.yahoo.com/news/us-mexico-near-deal-cut-203152350.html

Consumers averse to GLP-1 costs, most unwilling to pay over $100 out of pocket per month: KPMG

 Though Eli Lilly and Novo Nordisk have recently taken steps to make their uber-popular GLP-1 drugs more affordable for certain consumers, many are still turned off by the meds’ sticker shock.

That’s according to the latest edition of KPMG’s annual survey (PDF) of American consumers, which polled 2,500 adults about their economic outlooks and views on a wide variety of sectors, including the healthcare and life sciences industries.

In the latter case, many of the questions revolved around GLP-1s. For example, respondents were asked about what they see as the biggest health benefits of the drug class. Two-thirds cited weight loss, while 56% pointed to the meds’ aiding in diabetes management, followed at some distance by those who highlighted GLP-1s’ potential help in cardiovascular disease and mental health.

Despite broad awareness of the drugs’ possible benefits, their price tags remained a major negative for consumers. When asked whether they’d be willing to pay higher insurance premiums if GLP-1s were covered, only a minority of all respondents said they would. 

Younger generations were more willing to pay higher premiums for access to the drugs: The 27% of Generation Z respondents who answered yes were the highest of all generational segments, with the percentage getting progressively smaller as ages increased, culminating in only 6% of baby boomers saying they’d be willing to pay the higher premiums.

The adults surveyed were overwhelmingly averse to out-of-pocket costs for GLP-1s. Only 20% said they’d be willing to pay up to $100 per month for the meds. Overall, per KPMG, more than 70% of those surveyed said they would not be willing to pay out of pocket for GLP-1s.

“Consumers in the age of precision medicine are discerning about their treatment choices, considering both efficacy and affordability. As they become more informed about GLP-1s, they recognize the benefits but are still wary of the personal cost,” Kristin Pothier, leader of KPMG’s U.S. life science sector, said in a statement to Fierce Pharma Marketing.

Consumer costs for GLP-1s like Novo’s Ozempic and Wegovy and Lilly’s Mounjaro and Zepbound vary widely based on insurance coverage and access points. Many insurers refuse to cover weight loss drugs—including Medicare and Medicaid—and even those that offer coverage can still charge hefty copays and deductible payments.

In recent months, however, both Novo and Lilly have taken steps to lower the costs of their GLP-1s for self-paying patients. Lilly currently offers various doses of Zepbound for $349 and $499 per month through its LillyDirect online pharmacy. Novo sells all doses of Wegovy for $499 to eligible self-pay customers through its own online platformin retail pharmacies and via several telehealth providers.

Though the self-pay discounts mark a steep drop from the drugs’ list prices—without insurance, a month’s supply of Wegovy, for example, is about $1,350—they’re still well above the $100 out-of-pocket maximum desired by KPMG’s survey respondents.

As Pothier added in the statement, “Pharmaceutical companies have the opportunity to continue educating consumers while seeking to strike an optimal price point.” 

https://www.fiercepharma.com/marketing/consumers-remain-averse-glp-1-costs-most-unwilling-pay-more-100-out-pocket-kpmg

Changes in weight, glycemic control after treatment with semaglutide or tirzepatide by discontinuation status

 Hamlet GasoyanW. Scott ButschRebecca SchulteNicholas J. CasacchiaPhuc LeChristopher B. BoyerMarcio L. GriebelerBartolome Burguera, Michael B. Rothberg



doi.org/10.1002/oby.24331

Abstract

Objective

The objective of this study was to characterize changes in body weight and glycated hemoglobin (in those with prediabetes at baseline) through 12 months by obesity pharmacotherapy discontinuation status.

Methods

This retrospective cohort study used electronic health record data from a large health system in Ohio and Florida to identify adults with overweight or obesity without type 2 diabetes who initiated injectable semaglutide or tirzepatide between 2021 and 2023. Treatment discontinuation was defined by a >90-day gap between exhaustion of previous supply and next dispense or end of study follow-up (December 2024) and was classified into early discontinuation (i.e., within 3 months of index date) and late discontinuation (i.e., within 3–12 months).

Results

We identified 7881 patients; 6109 received semaglutide, and 1772 received tirzepatide. A total of 80.8% had low maintenance dosages. Mean (SD) percentage weight reduction at 1 year was 8.7% (9.6%); and it was 3.6% (8.1%) with early discontinuation, 6.8% (9.1%) with late discontinuation, and 11.9% (9.2%) with non-discontinuation (p < 0.001). The mean (SD) absolute reduction in percent glycated hemoglobin at 1 year was 0.1 (0.4) with early discontinuation, 0.2 (0.4) with late discontinuation, and 0.4 (0.4) with non-discontinuation (p < 0.001).

Conclusions

The average weight reduction in this cohort was lower than that observed in the main phase 3 trials, likely because of higher rates of discontinuation and lower maintenance dosages.

https://onlinelibrary.wiley.com/doi/10.1002/oby.24331