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Thursday, September 4, 2025

Trump’s deadline to thin NYC mayoral race field in bid to stop Mamdani

 President Trump told a prominent New Yorker he wants long-shot mayoral hopefuls to bow out of the crowded field — by next week — in an attempt to stave off a socialist-run City Hall, The Post has learned.

Trump on Sunday rang up billionaire businessman John Catsimatidis, who has longtime ties to both Mayor Eric Adams and GOP nominee Curtis Sliwa, and voiced his dismay about what might happen to the Big Apple if Zohran Mamdani, the Democratic front-runner and proud socialist, wins in November.

President Trump speaks in the Oval Office on Sept. 3, 2025.REUTERS

“He is concerned about the New York City race. He does not want a socialist mayor, and he said, ’It’s not going to happen’ under his watch and wants a person under his watch,” Catsimatidis told The Post.

Trump, in a historic interjection by a president in a New York City mayoral race, said he wanted the field to be winnowed down in the next 10 days.

“At the end of the next 10 days, he wants the most qualified candidate to beat Mamdani,” Catsimatidis said.

Pressed on what the president said he would do at the deadline next Wednesday, the self-made mogul would only say, “He’s going to do whatever he has to do.”

Sources with knowledge of Trump’s thoughts on the race said the president is looking for ways to get Sliwa and Adams to step aside in favor of ex-Gov. Andrew Cuomo.

Eric Adams during a CUNY event in NYC.Matthew McDermott

The political maneuver was not based on Trump’s affection for Cuomo, but rather the series of polls since the primary that still have the former governor holding steady in second, followed by Sliwa in third and Adams a distant fourth.

The president and others in the party believe the ex-gov could make the best run at the socialist candidate, with polling showing Mamdani’s approval stalling and historically high negatives for a Democratic nominee, sources said.

Either candidate dropping out would give a boost to Cuomo, the sources added.

News of the phone call, details of which haven’t been previously disclosed, comes just a day after it emerged that top White House officials have been trying to find a gig for the beleaguered incumbent mayor, in a bid to convince him to drop his independent re-election run.

Andrew Cuomo attending the West Indies Day Parade on September 1, 2025.Stephen Yang for the New York Post
New York City mayoral candidate Zohran Mamdani greets a supporter before a press conference in New York City on September 2, 2025.REUTERS

Hizzoner has repeatedly vowed to stay in the race — with insiders telling The Post that his contempt of Cuomo for swooping into the mayoral election seemingly trumps his disdain at the idea of a Mamdani-run city.

“While other candidates have quit their jobs, Mayor Adams hasn’t walked away from his responsibilities,” said Adams campaign spokesperson Todd Shapiro. “He is running for re-election not because he needs another position, but because he believes deeply in the future of this city and has a proven record of getting things done.”

Sliwa — again on Thursday — slapped down the notion that he should bow out of the race.

“I am the only major-party candidate on the ballot besides Mamdani, and I am not dropping out because I will save this city,” he said.

https://nypost.com/2025/09/04/us-news/trump-sets-deadline-to-thin-field-in-crowed-nyc-mayoral-race-hes-going-to-do-whatever-he-has-to-do/

DOJ considering banning trans people from buying guns

 The Justice Department is discussing proposals to potentially block transgender Americans from buying firearms, sources told The Post.

In the wake of the deadly Minneapolis Catholic church shooting conducted by Robin Westman, who identified as a trans woman, DOJ officials are mulling options the Trump administration can take to restrict the 2nd Amendment rights of some Americans, sources familiar with the talks said.

Some DOJ members believe the move can be approved as a follow up on Trump’s executive order barring military service by transgender people.

The Post’s front page reporting the Minneapolis shooting.
Robin Westman purchasing a gun in surveillance video.KSTP / 5 INVESTIGATES
Westman seen in a 2021 video.Robin W/YouTube
One option could see Trump formally declare that people who identify as transgender are mentally ill and are not legally allowed to possess firearms, one Justice official told CNN.

https://nypost.com/2025/09/04/us-news/trumps-doj-considering-banning-trans-people-from-buying-guns/

J.Crew-Anon & The Mainstreaming Of Dissent

 by Cooper Davis via The Brownstone Institute,

During a recent family vacation over lobster, I watched my “vote blue no matter who” aunt, herself a paragon of New England liberal sensibilities from a leafy suburb outside Boston, argue with her Fox News–watching, burn-it-all-down brother about recent goings-on at HHS. “Just because Fauci lied about Covid,” she said, “doesn’t mean all science is fake; there’s something worth saving here.”

Meet J.Crew-Anon: affluent, educated, professional, skeptical but not nihilistic. They still read the Times and the Journal, but also subscribe to multiple Substacks and are daily imbibers of less “safe” publishers, like Brownstone.org. They triangulate. They parse information with friends and peers, seeing fact-checkers as either dangerous or useless or both. They are more interested in steelmanning the opposition than shouting it down. Having left one echo chamber—the legacy media consensus—they are wary of entering a new one. They know the dangers of epistemic bubbles, and they prize conversations that test their skepticism rather than simply confirm it. They can be angry, but not anarchic. They have mortgages, careers, kids, PTA meetings—and a deep distrust of institutions that used to feel unshakable.

If this archetype sounds unfamiliar, it may be because your friends and colleagues aren’t comfortable enough yet to reveal the depth of their own skepticism. J.Crew-Anon thrives quietly, often hidden in plain sight, surfacing only when the cost of dissent has fallen low enough to make honesty safe.

What J.Crew-Anon represents isn’t entirely new. Up until the early 2000s, the United States had a vibrant anticorporate, antiauthoritarian left that acted as a watchdog against pharmaceutical, corporate, and governmental overreach. Ralph Nader’s consumer rights campaigns, feminist health collectives publishing Our Bodies, Ourselves, and ACT UP confronting the FDA and NIH during the AIDS crisis all carried the same distrust of official reassurances, and the same heated insistence that ordinary people could see through corporate spin.

That movement didn’t disappear, but it was blunted by the professionalization of NGOs, captured by the Democratic Party’s neoliberal consensus, and gradually domesticated into policy shops. But its sensibility never dissipated. What we are seeing now is its reemergence in unexpected form. J.Crew-Anon revives that watchdog instinct, this time distributed across suburbia, podcasts, Substack feeds, and social networks, rather than marches and union halls.

As of 2025, what was previously called the mainstream media is no longer mainstream. A growing swath of ordinary folks—educated, suburban, professional—have quietly lost confidence in legacy information outlets, and the institutions and industries they have long served.

Speaking as executive director of Inner Compass Initiative, I can say that the movement of which we are a part is made up of completely normal, mostly non-ideological people, looking critically at the mental health system and working towards its reform, along with building parallel frameworks of succor and support. Many of us have learned the hard way that the experts don’t always know everything, but there’s not a single person among our ranks who feels all credentialed expertise is worthless, or that non-experts are right by default.

Among us are doctors, lawyers, town planners, small business owners, pilots, CEOs and teachers. We are indistinguishable from other broad demographics, such as “people who prefer cats more than dogs” or “people who like spicy food.” But now that broad outlook—distrust in legacy authority of all sorts—is spreading.

J.Crew-Anon exists not just because so many narratives once dismissed as “conspiracies” have turned out to be true. The second-order effect is that denial or minimization of these “inconvenient truths” is no longer a prerequisite for being invited to the neighborhood BBQ. Over the last 12–18 months, the social cost for defecting from the world depicted by legacy media and adjudicated by Harvard and Yale has been reduced to less than nothing across much of the middle and upper classes.

I don’t need to list off the various egregious counterfactuals here, but suffice it to say that the “wrong opinion” is no longer the same thing as the “actually true opinion,” and examples abound. The Twitter Files revealed government–tech collusion. Monsanto’s glyphosate cover-ups, PFAS contamination. Social media’s own architects admitting their platforms cause immense harm. Even opposition to Covid school closures, once derided, is now treated as laudable in the New York Times itself.

Closer to my own vantage point, the issue of psychiatric drug withdrawal offers an instructive vignette: For decades, patients who struggled to come off antidepressants were told withdrawal didn’t exist. Over the last couple years, we’ve seen a growing consensus across mainstream media that SSRI withdrawal not only exists, but might actually contribute to climbing rates of diagnosis (due to withdrawal symptoms being mistaken for “relapse” of depression, anxiety, or whatever the drug was originally prescribed for).

In response to this shift in public sensibility, industry pushed out a sham review in the form of Kalfas et al.’s JAMA Psychiatry paper, dismissing the problem as minor. But only a month prior, Awais Aftab, in the pages of the New York Times itself, explicitly warned against this exact folly by pointing out the obvious: if the field refuses to acknowledge what patients have come to experience for themselves, they should not then be surprised that those same people decide, occasionally with gusto, that RFK, Jr. does a better job of looking after their health and safety than the APA does. Can you blame them?

Psychiatric withdrawal is just one instance of a much older pattern. In the era of Ralph Nader’s consumer crusades or ACT UP’s battles with the FDA, ordinary citizens forced institutions to acknowledge what they had long denied. The difference now is scale. Where once denial and reversal were confined to niche activist domains, today the cycle—grassroots exposure, institutional minimization, reluctant admission—runs through psychiatry, nutrition science, pandemic response, and even foreign policy. That expansion of scope is what makes the current moment qualitatively different.

This is the environment that gave rise to the MAHA movement. It is not a top-down, anti-science reactionary crusade, as critics caricature it, but a crowdsourced, populist response to scientific and medical authority overextending itself to the point of credibility collapse.

Every issue in the coalition—psychiatric drug harm (including but not limited to withdrawal), environmental toxins, nutrition guidelines, food safety, digital addiction—has its own movement: its own subculture, heroes, villains, court cases, history. In the past, grassroots movements like these would coalesce quietly, then events in the news would eventually force a broader acknowledgement of their existence. Once they made some noise, industry took notice, and used media, professional guilds, and lobbying to marginalize them. Once securely placed in the “kooky corner” with the other “anti-” types, they often faded as leaders aged out, factions turned insular, and institutions co-opted whatever inoffensive, non-threatening energy and ideas they possessed.

The internet has altered that cycle: forums, Subreddits, Facebook groups—archives of lived experience, link dumps and independent research that do not vanish, but accumulate, compound, and refine. The next generation inherits a body of knowledge instead of starting from scratch. Whether that makes the emergent movements and political coalitions more durable remains to be seen. But it does make them more obvious.

Politics, at its core, is transactional: find a constituency, hear its grievances, and represent it in exchange for support. Kennedy’s only innovation was listening to the growing ranks of people convinced that the healthcare system itself is inflicting needless harm. Had he not done so, someone else would have. That inevitability—not his persona—made him a vehicle for the energy of J.Crew-Anon.

From this perspective, MAHA might be best understood as a window into a vast, loosely collected ecosystem of people and organizations that are, at this moment, attempting to march in lockstep for shared goals: informed consent, regulatory capture, industry overreach, etc. Like any insurgent movement, it already carries barnacles: opportunists, cranks, hangers-on. Whether it can scrape them off is an open question. If not, more established and disciplined institutions will siphon off bits and pieces on the promise of more effective representation. Either way, the underlying constituency is real, and it isn’t going away, and those who don’t understand what it is—or who it is—are already in danger of losing their own credibility.

For any such unfortunates reading this, a cheat sheet: J.Crew-Anon is not programmatically conservative, though they share suspicion of media and bureaucracy. They are not progressive, even though they live in liberal metros and heartily support diversity and pluralism. They are not centrist, if centrism means deferred trust. They are something else: a post-institutional middle.

They are educated, mid-career professionals—often suburban or urban upper-middle class. They still work demanding jobs, raise kids, join HOAs, shop at Costco, play pickleball. But they no longer believe that institutions have credibility. Instead, they filter information through group chats, endless online sources, and their own judgment. They are pragmatic, not utopian. Skeptical, not anomistic. They respect individual autonomy. They know institutions lie—but they also know truth exists and is worth salvaging. That balance—conditional trust, selective belief—makes them powerful.

What’s striking is not that they believe wild things, but that they now take for granted knowledge once known only to obsessives: sugar myths, saturated fat controversy, the concerning pervasiveness of endocrine disruptors and PFAS and glyphosate, the revolving door between regulators and industry, the opioid crisis as a consequence of captured agencies, dopamine-driven design in social media, clinical trial corruption and conflicts, even the (potential) epidemic of psychiatric drug withdrawal.

Examples of this stripe of credible-but-not-credulous, people abound: NIH Director Jay Bhattacharya is perhaps the highest profile one; Jillian Michaels and Andrew Huberman on health; Nina Teicholz and Gary Taubes on nutrition and food; Marc Andreessen and David Sacks from the VC world; journalists like Glenn Greenwald and Matt Taibbi, who shifted from prestige outlets to exposing collusion between government and media; Walter Kirn and David Samuels channel this sensibility into County Highway, which one might consider the flagship chronicle of this cultural shift.

Examples aside: these people manage to straddle mainstream consensus reality while also recognizing that much of it is an illusion. J.Crew-Anon is a new gestalt, not perfectly reflected in a single character. It is a new intellectual and political class that, unlike others, is prone to growth but unlikely to shrink. Once you’ve migrated to the side of skepticism, you tend not to regain your faith in institutions, and the J.Crew-Anon template is for people who don’t need to trust institutions in order to make use of them, or even care deeply about them.

But because of its preoccupations with superficial acronyms and characters, the establishment itself is still failing to understand what it is dealing with. The gleefulness with which they herald dysfunction among the high-profile expressions of these ideas is unchecked by any awareness that this is a bottom-up movement, largely fueled by fairly recent defectors from the political left. Instead, every sign of dissidence is rendered as some version of a pesky, top-down, “right-wing fascism” or MAGA.

Perhaps the mainstream press, the institutions, and the still-credulous among the populace are holding onto hope that this is a temporary spasm of weirdness that will fade away in the coming years. There does seem to remain a chortling conviction that “normal” will return to the land in time. But that will not happen. “Normal” hung on as long as it could in a post-internet era, and ultimately blew away after Covid pulled up the last few remaining stakes holding down the threadbare tent of 20th century consensus reality. 

The question is not whether J.Crew-Anon exists. It does. The question is who it will select as its champions, and to what end. Whether its ascendance will be enough to quell the growing rebellion from working-class ranks who are not nearly as polite, elitely educated, or establishment-adjacent as their J.Crew-Anon neighbors remains to be seen.

https://www.zerohedge.com/political/jcrew-anon-mainstreaming-dissent

House Approves Establishing New Committee To Investigate Jan. 6 Capitol Breach

 by Joseph Lord via The Epoch Times,

The U.S. House of Representatives on Sept. 3 approved the establishment of a new committee to investigate the Jan. 6, 2021, breach of the U.S. Capitol.

In a 212–208 vote, the House approved a rule that wrapped in the new panel as well as a provision endorsing the House Oversight Committee’s investigation into deceased sex offender Jeffrey Epstein.

Included in the rules package was a resolution by Rep. Barry Loudermilk (R-Ga.) authorizing the creation of the panel, which will be chaired by Loudermilk. The new panel falls under the jurisdiction of the House Judiciary Committee.

It’s the second panel approved by Congress to investigate the events on the day of and leading up to the Jan. 6, 2021, Capitol breach, during which a crowd of President Donald Trump’s supporters attending the “Stop the Steal” rally entered the Capitol.

The incident delayed the vote to certify President-elect Joe Biden’s victory in the 2020 election. Lawmakers reconvened to finish the proceedings after the crowd had been cleared from the building.

The vote fulfills a promise made by House Speaker Mike Johnson (R-La.) at the start of the 119th Congress to form a new subcommittee on the subject, as its Democrat-led predecessor had long faced allegations of bias and partisanship.

The resolution to authorize the new panel was introduced by Loudermilk—who was targeted for investigation by the previous Jan. 6 panel for a tour he gave of the Capitol complex in the days ahead of the Jan. 6 rally—a day before the House left for its August recess.

In a statement ahead of the recess, Johnson, who gave his backing to the bill, said, “House Republicans are proud of our work so far in exposing the false narratives peddled by the politically motivated January 6 Select Committee during the 117th Congress, but there is clearly more work to be done.”

Johnson said that the resolution would allow Congress to “continue our efforts to uncover the full truth that is owed to the American people.”

The first panel was approved by Democrats in 2021. Controversially, then-House Speaker Nancy Pelosi (D-Calif.) did not allow then-House Minority Leader Kevin McCarthy (R-Calif.) to select which Republicans would sit on the panel.

Instead, Pelosi chose two Republicans critical of Trump to sit on the panel: Rep. Liz Cheney (R-Wyo.) was named ranking member, and Rep. Adam Kinzinger (R-Ill.) was also appointed to the GOP side.

The panel was highly critical of Trump, concluding in their final report that he was responsible for the events of the day and failed to take appropriate action to disperse the crowd after they entered the building.

Trump has maintained that he was not responsible. He and his allies have pointed to the administration’s offer to send National Guard to the Capitol ahead of the Jan. 6 rally. According to then-House Sergeant at Arms Paul Irving, a request from the Capitol Police for National Guard support was denied because Pelosi “would never go for it.”

https://www.zerohedge.com/political/house-approves-establishing-new-committee-investigate-jan-6-capitol-breach

Blood Test Detects ALS Years Before Symptom Onset

 A blood test that detects proteins unique to amyotrophic lateral sclerosis (ALS) can identify those with disease years before symptoms appear, new research suggests.

"We had always assumed that ALS was a rapid disease that starts 12 to 18 months before symptom onset," study investigator Alexander Pantelyat, MD, associate professor of neurology at the Johns Hopkins University School of Medicine, said in a press release. "But when we look at our findings, we see this has been a process that goes on for a decade or so before the patient ever steps into the doctor's office or clinic."

The study was published on August 19 in Nature Medicine.

'Distinct Molecular Signature' 

A reliable method for diagnosing ALS has been elusive, the researchers noted. Existing biomarkers for ALS rely on a single measurable characteristic, such as neurofilaments, for diagnosis and monitoring disease progression. Finding an accurate biomarker for ALS before symptoms start could aid in patient care, clinical trials, and better understanding the mechanisms of the disease.

What's more, those diagnosed with ALS typically live for 2-4 years after symptoms begin, but these findings suggest the disease may start 10-15 years before symptoms appear.

In a cross-sectional study, researchers enrolled 281 patients with ALS and 258 participants from a healthy control population from the University of Turin and the National Institutes of Health. Plasma samples were taken from patients and participants, and researchers used a proteomics platform to identify proteins specific to ALS from a total of 2886 proteins.

Using machine learning, researchers developed a best-performing model of proteins based on data from a training set of 181 patients with ALS and 172 healthy participants as well as 137 patients with other neurologic diseases. The model was then tested on samples from 48 patients with ALS, 42 healthy participants, and 33 patients with other neurologic diseases.

"It's crucial for patients and their families to be able to discern between ALS and other conditions for diagnostic clarity, prognostic understanding and eligibility to enroll into the appropriate clinical trials," Pantelyat said.

Overall, a set of 33 proteins were identified as a "distinct molecular signature" for ALS that differentiated ALS cases from healthy participants and from other neurologic diseases such as corticobasal syndrome, dementia, Lewy body dementiamultiple system atrophyParkinson's disease, and progressive supranuclear palsy.

This model, when combined with other clinical information about the patient, was highly accurate in distinguishing people with ALS from healthy participants and those with other neurologic diseases, with an area under the curve of 98.3%.

The machine learning model was also validated across a group of 13 patients with ALS and 23,601 healthy participants in a control group from the UK Biobank, identifying 82.7% of patients with ALS and 99.3% of participants in the control group.

Among 110 patients and healthy participants in whom plasma samples were taken before ALS symptoms developed, the risk score for ALS generated by the model increased as the time to symptom onset came closer. The ALS risk score was not associated with aging because the association was not seen among healthy participants or in patients with other neurologic diseases.

Potential for Early Diagnosis

Because the protein panel can detect ALS at the earliest stage of disease, it may one day serve as a biomarker for ALS similar to biomarkers seen in the early detection of Alzheimer's disease before symptoms appear.

"We see the light at the end of the tunnel here, and that target is an approved and available blood test for ALS," Pantelyat said. "With a test that allows for earlier detection of ALS, we have opportunities to enroll people in observational studies, and by extension, offer promising disease-modifying — and hopefully disease-stopping — medications, before ALS becomes debilitating."

Some of the proteins in the panel, such as the neurofilament light (NEFL) protein, were already known to be associated with ALS, while 16 additional proteins were identified through predictive modeling as being associated with the disease. The researchers made their data available publicly "to encourage and advance biomarker research" for ALS.

"Fifteen years of cross-institutional collaboration went into this work," Pantelyat said. "Large-scale partnerships are the lifeblood of research. They're what will lead to effective diagnostics and ultimately effective treatments for devastating diseases like ALS."

This study was supported by the Intramural Research Program of the National Institutes of Health, the National Institute on Aging, the National Institute of Neurological Disorders and Stroke, the Division of Intramural Research of the National Institute of Allergy and Infectious Diseases, Merck Sharp & Dohme Corporation, and the Italian Ministry of Health. Pantelyat reported no relevant financial relationships. 

https://www.medscape.com/viewarticle/blood-test-detects-als-years-before-symptom-onset-2025a1000ngm