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Wednesday, August 8, 2018

Canopy Growth: Pot-based medical pet products closer


Canadian pets are a few steps closer to getting their paws on pot-based medical treatments in Canada as more cannabis companies research marijuana’s efficacy for companion animals.
Canopy Growth Corp. is the latest medical marijuana company to enter the potentially lucrative pet market with its announcement this week that it will embark on a Health Canada-approved clinical trial to research the use of cannabis-based products to treat animal anxiety.
The Canadian Veterinary Medical Association’s national issues and animal welfare manager says there has been a flurry of cannabis-related pet research as Canada’slaws on recreational cannabis become clearer as the country prepares for legalization in October.
Dr. Shane Renwick says its veterinarian members have gotten a lot of queries from clients looking for cannabis-based treatments for their pets’ ailments, such as pain, but there is no legal avenue for them to prescribe pot and not enough clinical evidence to support it.
He says the association is hopeful that the government will eventually approve some cannabis-based veterinary health products that its members can prescribe for their pet clients, and each clinical trial approval brings them one step closer in the process.
Canopy says it got the green light from the Veterinary Drug Directorate of Health Canada for its research into the use of cannabidiol, also known as CBD, enriched oil to treat anxiety in certain animals.

Cantor Fitzgerald Starts Pacific Biosciences at Overweight


https://bit.ly/2ATGi4C

Mylan Forms Strategy Review Panel, Evaluating Alternatives to Unlock Value


Global pharmaceutical company Mylan N.V.’s (NASDAQ: MYL) board of directors today released the following statement:
Over the past decade, Mylan’s Board of Directors and management team have turned Mylan into a leading global platform with a highly-diversified portfolio of products across broad therapeutic areas and geographies. Our long-term strategy and management’s continued execution have consistently served the best interests of all of our stakeholders.
Our international business, in which we expect continued growth, now represents more than 60% of the company’s global sales. These global growth expectations are in contrast to the negative trends and dynamics playing out in the US market place – which we believe are unsustainable for the healthcare system over the long-term but which we believe Mylan is uniquely well positioned to successfully weather and navigate.
Our confidence in the future is bolstered by the fact that the company continues to generate significant, global durable cash flows, enabling us to continue investing in new initiatives for further long-term growth and building on our unique global platform. Over the last several years, the combination of our internal initiatives, outstanding execution and external M&A strategy have completely diversified and changed the profile of our company by shifting the core from a US-centric operation to a sustainable global presence.
With this said, we believe that the US public markets continue to underappreciate and undervalue the durability, differentiation and strengths of Mylan’s global diversified business, especially when compared to our peers around the globe. Therefore, while we will continue to execute on our best-in-class, long-term focused sustainable strategy, the Board has formed a strategic review committee and is actively evaluating a wide range of alternatives to unlock the true value of our one-of-a-kind platform. The Board has not set a timetable for its evaluation of alternatives and there can be no assurance that any alternative will be implemented.

Quorum Health reports Q2 EPS (92c), consensus (65c)


Reports Q2 revenue $472.6M vs. $530.1M last year. On a same-facility basis, admissions decreased 3.0%, adjusted admissions decreased 1.8% and net operating revenues per adjusted admission increased 5.3% compared to the same period in 2017.

Rite Aid and Albertsons agree to terminate merger agreement


https://bit.ly/2M1hnRX

GoodRx valued at about $2.8 billion after Silver Lake investment


Silver Lake, the technology-focused private equity firm, has taken a stake in health-technology startup GoodRx valuing it at about $2.8 billion, according to three people familiar with the matter.
Silver Lake will own about one-third of the company, two of the people said, who asked not to be named because details of the deal are private. The investment will make Silver Lake the largest shareholder in GoodRX, one of the people said. GoodRx and Silver Lake declined to comment on the financial terms of the deal.
CNBC first reported that GoodRx was in acquisition talks for up to $3 billion in June, with interested buyers including health distribution giant McKesson.
GoodRx offers people without health insurance, or with high deductible plans, a way to shop for drugs at lower prices than they’d find otherwise in the pharmacy. The company takes a percentage of the transaction when consumers use its drug discount cards. It does that through its relationships with pharmacy benefits managers.
“We’re excited to welcome Silver Lake to the GoodRx family,” said Doug Hirsch, Co-CEO of GoodRx, in a statement. “Silver Lake’s proven track record as a technology investor will advance GoodRx’s mission of making healthcare more affordable for all Americans.”
Silver Lake joins current GoodRx investors Francisco Partners and Spectrum Equity.
“GoodRx’s significant, growing digital platform has simplified the prescription drug market through increased transparency and lower prices in a short amount of time,” said Greg Mondre and Adam Karol, of Silver Lake in a statement.

Emergent BioSolutions Makes Up for Last Quarter


Last quarter, Emergent BioSolutions‘ (NYSE:EBS) numbers looked downright ugly due to delayed timing of shipments of its products to the strategic national stockpile. With those shipments made up for in the second quarter, the numbers now look absolutely great, although the year-over-year increases are just as useless as last quarter.

Emergent BioSolutions results: The raw numbers

METRICQ2 2018Q2 2017YEAR-OVER-YEAR CHANGE
Revenue$220.2 million$100.8 million118%
Income from operations$66.8 million$8.5 million683%
Earnings per share$0.98$0.11990%
DATA SOURCE: EMERGENT BIOSOLUTIONS.

What happened with Emergent BioSolutions this quarter?

  • Combining the two quarters, revenue was up 55% in the first half of the year compared to the same period last year thanks to acquisitions of smallpox vaccine ACAM2000 and anthrax treatment raxibacumab late last year. Year-to-date adjusted earnings per share increased 147%.
  • Second-quarter revenue from contract manufacturing, which wasn’t affected by the shipment timing issue, increased 46%, which was mostly due to the manufacturing plant the company got in the ACAM2000 deal with Sanofi (NYSE:SNY). Emergent plans to invest up to $50 million over the next three years in one of its other manufacturing plants to further increase revenue from contract manufacturing.
  • Emergent BioSolutions set up a collaboration with Profectus BioSciences and the Coalition for Epidemic Preparedness Innovations to develop a vaccine against Nipah virus, which Emergent has an option to license.
  • A phase 1 trial for ZIKV-IG as a treatment for the Zika virus started this month.

What management had to say

Emergent’s CEO Daniel Abdun-Nabi highlighted the potential expansion of stockpiles for chemical, biological, radiological, nuclear, and explosives (CBRNE) countermeasures in Europe discussed at the June summit of the European Council:
CBRNE threats were a major topic, particularly in light of the recent nerve agent attacks in the United Kingdom. The 28 EU Head of States formally endorsed a strategy for dealing with CBRNE threats in Europe. This was published in the European Commission joint communication, which stressed the need to accelerate full implementation of the EU CBRNE action plan. That plan contemplates that each member state will establish stockpiles of medical countermeasures and take steps to enhance access to, and enable rapid deployment of, those stockpiles.
Given Emergent’s product offerings, there’s obviously a big opportunity to grow sales in Europe, but Abdun-Nabi pointed out that we’re still early in the process. “We don’t have a lot of details on how this is going to actually unfold, but as we get into deeper conversation with member states, we will have a much better understanding for the policy and directives that they’ll be launching over the course of the next 12 to 24 months,” Abdun-Nabi said.

Looking forward

Management is sticking with its previously announced 2018 revenue and earnings guidance and said it expects third-quarter revenue to fall in the $165 million to $190 million range.
To get to its goal of $1 billion in sales in 2020, management is going to have to make another acquisition or two, which is still in the works for this year. The company also needs to negotiate the next contract for ACAM2000, which will hopefully come with a larger volume or price (or both!) than the contract it inherited from Sanofi. And there’s potential to start generating revenue from NuThrax, the follow-on to its anthrax vaccine BioThrax, after the FDA approves the Emergency Use Authorization that’s scheduled to be filed by the end of this year.