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Sunday, January 29, 2023

Healthcare ranked lowest for employee satisfaction

 Healthcare ranked last for employee satisfaction compared to 27 other industries, according to the 2023 Healthcare Experience Trends Report from Qualtrics.

The survey of 3,000 healthcare employees across 27 countries paints a grim picture, reporting that only half of healthcare employees believe they are paid fairly, 38% report they are at risk of burnout and 39% are considering leaving their organizations. Qualtrics also surveyed 9,000 consumers, finding that hospitals ranked among the lowest across industries for satisfaction.

The study also found that while patients appreciate digital healthcare experiences, the human element was paramount.

“What’s important to understand about healthcare today is the extraordinary people that continue to show up every day—people who are intrinsically motivated to help others and support their teams. Caring for others who may be having the worst day of their life is already hard,” Adrienne Boissy, M.D., Qualtrics' chief medical officer, told Fierce Healthcare in an email.

“I think healthcare environments start to go a bit sideways when employees don’t feel they are paid fairly, when time is spent doing menial tasks (like typing, completing forms, repeating information, or filling in the electronic health record at night when they should be spending time with their families), and when their values are conflicted in life and work," Boissy said.

Boissy, who also works as a practicing neurologist at Cleveland Clinic, said that other industries are moving to standardize their experience platforms, consolidate tech stacks and “obsessing over their customers in ways healthcare has not … yet.”

The data point to hope that patients are open to better relationships with healthcare, with 79% of respondents saying they trust hospitals. Small shifts in how patients and staff are viewed can make big differences in morale, Boissy emphasized.

She lists simple bits of technology that can streamline clinicians' workflow while directing them toward the patients most in need of their care. Things like ambient listening and transcription of clinical notes, leveraging virtual care to increase schedule flexibility and prioritization of alerts and safety alarms are “low-hanging fruit," Boissy said.

“For employees, they often feel unknown by the system they work within,” Boissy said. “They are not sure their values align. I see healthcare missing opportunities to humanize at scale like remembering birthdays and work anniversaries, setting the stage at onboarding to focus on caring for people, not learning technology systems, pausing in silence and creating rituals to emotionally decompress staff and leveraging every single opportunity to shower gratitude on caregivers.”

Four overall trends revealed in the report showed a careful balancing of human and machine. Both patients and staff revealed that digitizing and humanizing every experience made stronger connections, people felt heard when their feedback was integrated into hospital functions and trust is earned when memorable patient experiences were achieved. Taking note of other industries was also seen as an important way for hospitals to forge their own path into the future.

As far as feedback goes, 61% of patients felt that healthcare providers needed to do a better job at listening, and 69% said the same thing about insurance companies.

For scheduling appointments, 36% of patients said they would prefer to talk to someone on the phone, and 26% said they would prefer self-service on their phone. For seeking minor medical advice, 48% preferred in-person care and 25% preferred the phone.

“Healthcare scored lower than the cross-industry average in workplace efficiency, which asked about both the processes themselves and the environment,” Boissy said. “In other words, do managers help prioritize the work to focus on? Do they remove barriers? This means the solutions have to equip managers with successful skill sets for their teams and the process itself needs constant re-evaluation and testing.”

When it comes to patients, Boissy says they need to be given more input, more control: “We still build buildings without asking for meaningful patient input.”

https://www.fiercehealthcare.com/health-tech/qualtrics-survey-finds-only-half-healthcare-employees-think-they-are-paid-fairly

WHO Suddenly Updates Medicines List For Nuclear Emergencies

 by Caden Pearson via The Epoch Times,

The World Health Organization (WHO) on Friday released recommendations on how to acquire and manage medical supplies for the treatment of exposure to radioactive materials in emergencies.

The report sets out for countries and governments how to develop and maintain a national stockpile of specific medical supplies that can lower risks and treat injuries caused by radiation.

Maria Neira, the head of the WHO’s Public Health and Environment department, emphasized the importance of having “ready supplies” of crucial drugs developed over the last decade.

“In radiation emergencies, people may be exposed to radiation at doses ranging from negligible to life-threatening. Governments need to make treatments available for those in need—fast,” Neira said in a statement.

It’s the first time the publication has been updated since 2007.

“This updated critical medicines list will be a vital preparedness and readiness tool for our partners to identify, procure, stockpile, and deliver effective countermeasures in a timely fashion to those at risk or exposed in these events,” said Dr. Mike Ryan, the executive director of WHO’s health emergencies program.

The medicines listed in the publication for a national stockpile include only those specifically used today to treat human over-exposure to radiation, according to the WHO. Other typical lists of medical supplies for stockpile would include generic supplies like personal protective equipment (PPE), trauma kits, fluids, antibiotics, and painkillers.

The WHO stated its data, prepared in annual reports, showed that many countries are still unprepared for radiation emergencies.

Stockpile

The report focussed on which medicines should be stockpiled and how they should be stored and managed, as well as the role that different organizations play in preparing for and responding to emergencies.

The WHO noted that a collection of medical supplies commonly found in a radiation emergency stockpile include stable iodine to protect the thyroid from radioactive iodine, chelating agents such as Prussian blue to remove radioactive caesium from the body, and decorporating agents like calcium-/zinc-DTPA to treat internal contamination with transuranium radionuclides.

Additionally, there are also cytokines included to help reduce the damage to bone marrow in cases of acute radiation syndrome and other medicines to treat symptoms such as vomiting, diarrhea, and infections, according to the WHO.

The report discusses emerging treatments and medical countermeasures, such as studies identifying new cellular and molecular pathways and means of administrating drugs that may be exploited for novel treatments and new products for use during a radiation emergency.

An image of a small round and silver capsule containing radioactive Caesium-137 that went missing in transportation between a mine site north of Newman and the north-eastern parts of Perth between Jan. 10–16, obtained on Jan. 27, 2023. (AAP Image/Supplied by Department of Fire and Emergency Services WA)

Radiological and Nuclear Emergencies

According to the WHO, a radiological or nuclear emergency is a situation that negatively impacts human life, health, property, or the environment.

The report considers possible scenarios for radiological and nuclear emergencies, including accidents at nuclear power plants and nuclear warfare.

An accident at a nuclear power plant, medical or research facility, or accidents during the transport of radioactive materials are examples of accidental radiological and nuclear emergencies that could occur, according to the WHO.

They can involve a number of situations, such as nuclear power plant accidents such as Chernobyl and Fukushima. Situations can also involve accidental exposure to uncontrolled radiation sources, and accidentals while transporting radioactive materials.

One such incident happened in Australia recently, where a small, solid capsule measuring 8 mm by 6 mm was thought to have dropped off a truck during transportation from a mine to Perth. The capsule is radioactive and can potentially cause severe skin burns and illness. It is reported to emit a level of radiation equivalent to receiving 10 x-rays in one hour, at 2 millisieverts per hour.

Radiation emergencies may also occur in conjunction with conventional emergencies, natural disasters, military conflicts, or malicious acts involving radiation sources, the WHO noted.

https://www.zerohedge.com/medical/who-suddenly-updates-medicines-list-nuclear-emergencies

"We Will Root Out The Deep State" - Trump Begins 2024 Campaign In NH, SC

 by Frank Fang via The Epoch Times,

Former President Donald Trump visited two early-voting states New Hampshire and South Carolina on Jan. 28, hitting the campaign trail for the first time since announcing his 2024 bid for the White House in November last year.

“The 2024 election is our one shot to save our country, and we need a leader who is ready to do that on day one,” Trump said in a speech in Columbia, South Carolina.

“We need a fighter who can stand up to the left, who can stand up to the swamp, stand up to the media, stand up to the deep state.”

“Am I allowed to say stand up to the RINOs?” Trump continued, referring to an acronym for “Republican in Name Only.”

“To stand up to the globalists and China, and stand up for America. And that’s what we do, we stand up for America,” Trump added.

“You need a president who can take on the whole system and a president that can win.”

Former President Donald Trump, joined by Sen. Lindsay Graham (R-S.C.) (R), and South Carolina Gov. Henry McMaster (L), speaks at a 2024 election campaign event in Columbia, S.C., on Jan. 28, 2023. (Logan Cyrus/AFP via Getty Images)

The former president added, “Together we will complete the unfinished business of making America great again.”

Trump also unveiled his South Carolina leadership team, which is to be headed by South Carolina Gov. Henry McMaster. Others named to the leadership team include the state’s Lt. Gov. Pamela Evette, Sen. Lindsey Graham (R-S.C.), Rep. Russel Fry (R-S.C.), Rep. William Timmons (R-S.C.), Rep. Joe Wilson (R-S.C.), former U.S. Attorney Peter McCoy, and Trump’s former ambassador to Switzerland Ed McMullen.

“This campaign will be about the future. This campaign will be about issues,” Trump added, before criticizing President Joe Biden and his administration’s policies, such as border control, the drug crisis, and the economy.

“Joe Biden has put America on the fast track to ruin and destruction, and we will ensure that he does not receive four more years,” Trump added.

‘Marxist Hands Off of Our Children’

One particular issue that Trump said he will address if elected is education.

“We’re going to stop the left-wing radical racists and perverts who are trying to indoctrinate our youth. And we’re going to get their Marxist hands off of our children,” Trump said.

“We’re going to defeat the cult of gender ideology and reaffirm that God created two genders, called men and women.”

“We’re not going to allow men to play in women’s sports,” he added. “We’re going to save the dignity of women and we’re going to save women’s sports itself.”

Trump also said he will work to keep South Carolina’s presidential primary as the “first in the South,” which has taken place on Super Tuesday.

“It’s a very important state, first in the South,” Trump said. “And there were people wanting to move it. I said, ‘we’re not moving South Carolina.’”

Former President Donald Trump speaks at the New Hampshire Republican State Committee’s annual meeting in Salem, N.H., on Jan. 28, 2023. (Scott Eisen/Getty Images)

‘More Committed Now’

Before his speech in Columbia, Trump spoke at the New Hampshire Republican State Committee’s annual meeting in Salem, New Hampshire. He dismissed suggestions that he was off to a slow start in his campaign since announcing his third bid for the presidency.

“They said, ‘He’s not doing rallies, he’s not campaigning. Maybe he’s lost that step,’” Trump said in Salem.

However, Trump said, “I’m more angry now and I’m more committed now than I ever was.”

Trump announced Stephen Stepanek, the outgoing chairman of the New Hampshire Republican Party, would be joining his team as a senior advisor for his campaign in the Granite State. Chris Ager, a Republican National Committee member, has been elected the new chairman to replace Stepanek.

Primary Calendar

The former President criticized the Democrats’ efforts to change their primary calendar.

“From the very beginning, I’ve strongly defended New Hampshire’s first-in-the-nation primary status. I have been your defender,” Trump said. “I refuse to let any Republican, and there are some you know who they are. even think about taking that cherished status away.”

Honoring Biden’s wishes, the Democratic National Committee’s (DNC) Rules and Bylaws Committee passed a proposal in December making South Carolina the first vote in the party’s presidential nominating calendar. Under the proposal, South Carolina’s primary would be held on Feb. 3, followed by Nevada and New Hampshire on Feb. 6, Georgia on Feb. 13, and Michigan on Feb. 27.

Iowa is historically the first state to have a closed caucus, followed by New Hampshire with the first primary.

“We will root out the deep state and stop the weaponization of federal agencies because there’s a weaponization like nobody’s ever seen,” Trump added.

“We are going to take back our country, and we’ll take back the White House, and we’re going to straighten out the United States of America.”

https://www.zerohedge.com/political/we-will-root-out-deep-state-trump-begins-2024-campaign-new-hampshire-south-carolina

Future of Savings in Humira Biosimilars Drug Costs Are Low

 As a dozen Humira Biosimilars are set to enter the market this year, it seems to be unlikely that they will drive down drug costs in the future.

A recent analysis was published by Goodroot to examine these new biosimilars and it was projected that they will gain up to 5% market share in the first year, and reaching a maximum of 20-25% by 2026.

However, the unlikely chance they will drive down drug costs in the future is mainly due to competing companies in the biosimilars market, as well as a few other barriers.

In 2023, 12 biosimilar products are expected to enter the market and compete with AbbVie’s Humira.

Humira, produced by AbbVie for a variety of conditions including rheumatoid arthritis, is the highest-grossing drug of all time with $21 billion in annual global sales as of 2021. The cost to a patient and their insurer for the drug is often more than $80,000 annually.

However, AbbVie's patent expired in 2016 and legal maneuvering delayed biosimilars from reaching the market until agreements were struck to allow the sale of Humira biosimilars in 2023.

Now, with the introduction of competing biosimilars into the market, AbbVie is likely to increase their rebate above their current range for Humira’s net cost after discount to remain competitive in the marketplace and retain preferred status on most PBM formularies. They will also likely increase rebates for Skyrizi and Rinvoq to maintain a preferred position for all three products on formularies, the analysis said.

RemedyOne president Ralph Pisano, RPh, said in a Goodroot press release, "AbbVie, by our estimates, likely paid over $5 billion in rebates to pharmacy benefit managers (PBMs) in 2021. By increasing their rebates just 10%, AbbVie can match the net cost of biosimilar manufacturers, who also have to pay AbbVie royalties that effectively create a floor to how far they can lower prices."

He said Abbvie's rebate agreements with PBMs and plans "flat out stipulate that they cannot provide an advantage, such as lower out-of-pocket costs, for biosimilars on the patient's benefit."

Lastly, Pisano added that "given the challenging nature of conditions Humira treats, such as Crohn's disease, doctors will be reluctant to switch patients who have achieved stability on Humira to another medication, even if it offers cost savings."

The analysis shared potential payer strategies for biosimilars to Humira in overcoming this barrier.

  • Offer both Humira and biosimilars at parity.
    Some payers will continue to take a Humira rebate, allow access to lower cost biosimilars, and negotiate rebates with the biosimilar manufacturers. According to Goodroot, both OptumRx and Express Scripts have already opted for this strategy — and this will most likely be the leading strategy, given the concessions AbbVie has already made in contracting to allow both brand and biosimilars to coexist.
  • Prefer biosimilars and disadvantage.
    Humira Payers have the option to give up the Humira rebate and choose a biosimilar product with a lower net cost. While this is less likely, integrated health plans may be able to shift market share to lowest cost biosimilars.
  • Prefer Humira and disadvantage biosimilars.
    Other payers may continue to take Humira rebate and block access to lower cost biosimilars. This is the least likely option and too fraught with potential higher out-of-pocket costs for patients.

While market share for autoimmune treatments has historically been dominated by Humira, competition will largely depend on the economics dictated by AbbVie, Goodroot suggests. If they increase their rebate, it will be nearly impossible for biosimilars to make the cost impact that many are hopeful for.

Though, there may be a tipping point in biosimilar pricing where difference in the net cost will be significant enough to force payers to make their PBMs prefer the biosimilars. It's suggested that this lower net price must be coupled with a significant shift in market share to make up for the loss of Humira rebate.

https://www.managedhealthcareexecutive.com/view/most-viewed-articles-about-biosimilar-articles

OpenAI has hired an army of contractors to make basic coding obsolete

 OpenAI, the company behind the chatbot ChatGPT, has ramped up its hiring around the world, bringing on roughly 1,000 remote contractors over the past six months in regions like Latin America and Eastern Europe, according to people familiar with the matter.

About 60% of the contractors were hired to do what’s called “data labeling” — creating massive sets of images, audio clips, and other information that can then be used to train artificial intelligence tools or autonomous vehicles.

The other 40% are computer programmers who are creating data for OpenAI’s models to learn software engineering tasks. OpenAI’s existing Codex product, launched in Aug. 2021, is designed to translate natural language into code.

“A well-established company, which is determined to provide world-class AI technology to make the world a better and more efficient place, is looking for a Python Developer,” reads one OpenAI job listing in Spanish, which was posted by an outsourcing agency.

Previously, OpenAI trained its models on code scraped from GitHub, a repository site owned by its largest investor, Microsoft, which last week confirmed multi billion dollars in new funding first reported by Semafor. But in this case, OpenAI appears to be building a dataset that includes not just lines of code, but also the human explanations behind them written in natural language.

A software developer in South America who completed a five-hour unpaid coding test for OpenAI told Semafor he was asked to tackle a series of two-part assignments. First, he was given a coding problem and asked to explain in written English how he would approach it. Then, the developer was asked to provide a solution. If he found a bug, OpenAI told him to detail what the problem was and how it should be corrected, instead of simply fixing it.

“They most likely want to feed this model with a very specific kind of training data, where the human provides a step-by-step layout of their thought-process,” said the developer, who asked to remain anonymous to avoid jeopardizing future work opportunities. He has not yet been hired or rejected by OpenAI.

Sam Altman, OpenAI’s CEO, recently put the company’s headcount at 375 people, a tiny number compared to the thousands of staff at tech giants like Google and Facebook working on artificial intelligence. “I know I’m not supposed to brag about OpenAI,” he tweeted, touting the company’s “talent density.”

Altman did not appear to include contractors in that figure. But in OpenAI’s published research, the company has repeatedly noted the importance of outsourced labor in building its technology. “​Finally, we’d like to thank all of our contractors for providing the data that was essential for training the models,” a team of researchers at OpenAI wrote in a paper last year.

OpenAI declined to comment on its hiring practices.

With hundreds of programmers making a concerted effort to “teach” the models how to write basic code, the technology behind ChatGPT might be headed toward a new kind of software development as transformative to that sector as heavy equipment was to the construction industry.

OpenAI’s Codex technology is already being used in Microsoft’s GitHub to power a feature called “Copilot,” which essentially autocompletes lines of code for programmers.

Based on the work OpenAI’s contract programmers are doing, Copilot is about to become more like an autopilot, eliminating some of the rote work involved in writing code and ultimately eliminating some coding jobs altogether.

Silicon Valley executives envision products that allow creative people with little to no coding experience to build everything from web sites to video games simply by describing their visions to an AI algorithm.

“The hottest new programming language is English,” tweeted Andrej Karpathy, the former head of AI for Tesla.

The contractors OpenAI and other companies hire around the world are typically not computer science graduates, nor do they have advanced coding knowledge. Their skill is writing the kind of basic code that OpenAI hopes to one day automate.

The good news for these contractors: Despite the promising early results, there’s still a high likelihood that OpenAI hits major roadblocks in its efforts to automate coding, as tends to happen in AI development. Self-driving cars appeared imminent in 2013, for instance. Today, they seem like a distant possibility.

Title iconNOTABLE
  • OpenAI also hired a firm in Kenya to work on content moderation, helping ensure ChatGPT doesn’t spit out racist, violent, and sexually graphic content, TIME reported last week. Workers at the firm said they were scarred by disturbing content encountered during the job and that they lacked access to adequate mental health resources.
  • As U.S. tech companies look to cut costs domestically, they’re increasingly hiring software engineering talent in places like Latin America, which offers a cheap, educated workforce in the same time zone, according to Rest of World.

China approves two domestically developed COVID drugs

 

China has approved two domestically developed oral medicines for COVID-19 patients with mild symptoms, the National Medical Products Administration said on Sunday.

The drugs, used for treating adult patients with mild to moderate COVID-19 infections, have been developed by Simcere Pharmaceutical Group <2096. HK> and a unit of Shanghai Junshi Biosciences Co Ltd, the administration said in a statement on its website.

China abandoned its stringent "zero COVID" policy in early December after protests against it, allowing people to travel and the virus to spread rapidly throughout the country, boosting demand for COVID treatments.

https://www.marketscreener.com/quote/stock/SIMCERE-PHARMACEUTICAL-GR-119080130/news/China-approves-two-domestically-developed-COVID-drugs-42841866/

UK teen gets 11.5 years for hate-speech videos linked to Buffalo, Colorado mass shootings

 A British teenager who posted far-right videos that have been linked to mass shootings in Buffalo, N.Y., and Colorado Springs, Colo., was sentenced to 11 1/2 years on terrorism-related charges in the United Kingdom on Friday, the BBC reported.

Daniel Harris, 19, was convicted in December of five counts of encouraging terrorism and one count of possession of material for terrorist purposes for attempting to make a gun with a 3D printer.

Harris’s online posts — which Judge Patrick Field reportedly described as espousing “vile antisemitic, racist, misogynistic and homophobic views” — were shared online by Payton Gendron, who has pleaded guilty to fatally shooting 10 Black people at a Buffalo supermarket last May.

The British teenager’s videos, which called for the “total extermination of subhumans,” have also been linked to Anderson Lee Aldrich, who is accused of killing five people and injuring 25 more in a mass shooting at an LGBTQ nightclub in Colorado Springs in November.  

“What they did was truly appalling, but what they did was no more than you intended to encourage others to do when publishing this material online,” Field said at Harris’s sentencing on Friday, according to CNN.

“You intended to encourage terrorism, and it’s plain that what was being encouraged was lethal, racist and anti-Semitic violence, as well as violence against the gay community,” Field added, calling Harris’s posts a “stream of rightwing terrorist bile.”

https://thehill.com/policy/international/3833563-uk-teen-gets-11-5-years-for-hate-speech-videos-linked-to-buffalo-colorado-mass-shootings/