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Saturday, February 18, 2023

bioMérieux launches assay for simultaneous Salmonella and Listeria detection

 bioMérieux, an in vitro diagnostics expert, has announced the availability of GENE-UP ENVIROPRO, the only assay of its kind to simultaneously detect both Salmonella and Listeria from environmental swabbing, including PCR confirmation.

The solution provides cost savings, laboratory waste reduction, and a streamlined workflow to empower rapid and effective quality decisions.

Salmonella and Listeria workflows and assays available on the market consist of separate enrichments. With GENE-UP ENVIROPRO, users can test environments for both Salmonella and Listeria through one swab, one enrichment and one sample prep, improving overall sampling efficiencies and sustainability.

The GENE-UP ENVIROPRO assay is the result of bioMérieux’s xPRO programme – an innovation engine within bioMérieux partnering directly with industry leaders to rapidly develop, validate, and commercialise cutting-edge molecular assay to respond to emerging needs and provide solutions for new markets enhancing their overall quality programmes.

“The evolution of ENVIROPRO demonstrates our commitment to innovation through our xPRO programme and our success in building game-changing assays,” said Ben Pascal, Global Head xPRO Program at bioMérieux. “Bringing much-needed efficiencies to routine environmental monitoring will not only reduce costs for our end users but do so in a far more sustainable way, a key focus in the market.”

GENE-UP ENVIROPRO is designed to empower rapid and effective quality decisions with a best-in-class workflow that eliminates cumbersome DNA purification steps and reduces hands-on time.


The solution is an AOAC Performance Tested Method and can be applied across food industry verticals with applications including but not limited to dairy, dry fruits, nuts, seeds, berries, nutraceuticals, and multicomponent products (e.g., ready-to-eat meals).

For bioMérieux, the introduction of GENE-UP ENVIROPRO is the latest innovation supporting food safety to enter the market this year, after the debut of the GENE-UP QUANT Salmonella innovation, which was awarded as method of choice for Salmonella enumeration in the USDA’s Food Safety Inspection Service (FSIS) labs this summer.

"The introduction of these innovative assays mark an important step forward for the food industry, as they provide more detailed data and results in less time to enhance decision making throughout the production process," said Miguel Villa, VP of Industry Americas at bioMérieux. "We look forward to continued collaboration with our customers and partners to identify the existing and emerging issues that threaten food safety to develop solutions that not only meet these needs but improve public health worldwide." 

https://cleanroomtechnology.com/news/article_page/bioMerieux_launches_assay_for_simultaneous_Salmonella_and_Listeria_detection/206833

Ohio governor says FEMA will provide resources to East Palestine

 The Federal Emergency Management Agency will deploy federal resources to the site of a train derailment in Ohio, Gov. Mike DeWine (R) announced Friday evening after saying earlier this week that the agency had deemed the state ineligible.

“FEMA and the State of Ohio have been in constant contact regarding emergency operations in East Palestine. U.S. EPA [Environmental Protection Agency] and Ohio EPA have been working together since day one,” DeWine said Friday night in a joint state with FEMA Regional Administrator Thomas Sivak.

FEMA will supplement federal efforts by deploying a Senior Response Official along with a Regional Incident Management Assistance Team to support ongoing operations, including incident coordination and ongoing assessments of potential long-term recovery needs.”

A train operated by Norfolk Southern Railway derailed in the town of East Palestine on Feb 3, spilling several hazardous chemicals including vinyl chloride, a toxic substance used in production of plastics.

Earlier this week, DeWine said the federal agency had determined the town was not eligible for FEMA aid despite concerns about water and air quality, saying “although FEMA is synonymous with disaster support, they’re most typically involved with disasters where there is tremendous home or property damage” such as hurricanes or tornadoes. DeWine initially ordered the evacuation of residents in the affected area, rescinding the order five days later.

Both of Ohio’s senators, Sherrod Brown (D) and J.D. Vance (R) have separately urged DeWine to declare a disaster in the state, although Vance emphasized Thursday that such a declaration must not put the onus on the state and federal government rather than Norfolk Southern to be accountable for any damage.

The governor’s statement did not clarify whether the resources FEMA is making available would include the specific aid the agency initially declined. The Hill has reached out to DeWine’s office for comment.

https://thehill.com/policy/energy-environment/3864078-ohio-governor-says-fema-will-provide-resources-to-east-palestine/

GOP bill would jail publishers for distributing ‘sexually explicit materials’ to schools

 Publishers could face jail time and multi-thousand-dollar fines under a new GOP-led bill that seeks to crack down on the distribution of “sexually explicit materials” to schools and educational agencies.

A bill introduced this month by Rep. Cory Mills (R-Fla.) would amend the federal criminal code to prohibit a publishing house from knowingly furnishing “sexually explicit material” — a term that the legislation does not clearly define — to an elementary school or high school.

Publishing houses that violate the proposed law would be subject to a maximum $500,000 fine, while individuals in the company’s higher management would face similar monetary penalties, as well as up to five years imprisonment.

Mills’s bill, a copy of which was shared with The Hill, would also withhold federal funds from elementary or secondary schools that obtain or distribute published materials that contain a “sexually explicit visual depiction of any kind,” including photographs or drawings until those materials are “relinquished or destroyed” by the school.

State and local educational agencies, including school boards or boards of education, would also be barred from providing schools with books, magazines, newspapers or e-books that contain content deemed sexually explicit.

Restrictions do not apply to materials with “serious literary, artistic, political, or scientific value,” according to the bill.

Mills said in a statement earlier this month that his bill is a response to what he described as a coordinated effort by Democrats to “sexualize children in schools across the U.S.”

“The battlefield for the future of our society is being fought within the classrooms of American schools,” Mills said.

From school board meetings to new representation in local, state, and federal levels, Americans are waking up to the grim reality of woke indoctrination guised as a normal education,” he said. “No more.”

Republicans in state legislatures across the country have also argued that children are in need of protection from a liberal agenda they say is being pushed in schools, especially as it pertains to LGBTQ issues and identities.

More than 100 state bills filed this year would limit how educators and students can talk about sexual orientation or gender identity within school walls, according to the American Civil Liberties Union

Others seek to remove books from school libraries over alleged inappropriate content.

A whopping 1,600 books were banned in over 5,000 schools over the past year, according to a September PEN America report. More than 40 percent of the banned materials included LGBTQ characters or storylines.

“While we haven’t yet seen this particular legislation, it appears to be the latest salvo in a cross-country effort to strip away access to information in public education at every level through vague, ill-defined terminology,” Nadine Farid Johnson, managing director of PEN America Washington and free expression programs, told The Hill in a statement.

“Publishers, teachers, and librarians use established systems to determine the material appropriate for use in schools, and constitutional parameters already exist for determining what materials are not protected by the First Amendment,” she added.

Bills similar to Mills’s, introduced last year by Sens. Tim Scott (R-S.C.) — seen as a potential GOP contender in the 2024 presidential election — and Mike Johnson (R-La.), were viewed by LGBTQ advocates and allies as attacks against the community.

“In the past year, we’ve seen similar state-level laws result in removals of books about everything from art, to sexual education, to even the Holocaust,” Johnston wrote. “Unfortunately, those who push for censorship tend not to be concerned with how these kinds of laws can be broadly weaponized. They should be.”

A spokesperson for Mills told The Hill in an email on Friday that the new bill is not targeted toward any particular group.

“Preventing pornographic materials from being taught in classrooms is completely distinct from naming freedom of expression or conversations being had across our society about gender and sexuality,” the spokesperson said. “In our view, any interpretation of this bill as an ‘assault’ on LGBT+ individuals is reading through biased lenses and are disconnected from reality.”

The bill currently has seven GOP co-sponsors, including Rep. George Santos (R-N.Y.), who is the first openly gay nonincumbent Republican elected to Congress.

https://thehill.com/homenews/house/3863966-gop-bill-would-jail-publishers-for-distributing-sexually-explicit-materials-to-schools/

US calls off search for unidentified aerial objects shot down over Alaska, Lake Huron

 The United States has called off the search for two unidentified flying objects that were respectively shot down over Alaska and Lake Huron last week, The New York Times reported Friday. 

A U.S. official told The Times that conditions made locating the two objects too difficult despite trying to find them for days. 

The U.S. military shot down three objects last weekend in the aftermath of a Chinese balloon that drifted across the continental U.S. that officials say was designed to conduct surveillance. The first of the three objects was downed over Alaska, while the second was over a region of Canada and the third was over Lake Huron near Michigan. 

The objects have not been specifically identified, but President Biden said on Thursday that they were likely linked to a private company or researchers and not meant for surveillance as the Chinese balloon was. 

The official said Canada is continuing to search for the object that was taken down over the territory of Yukon. 

The object that was shot down over Alaska is believed to be about the size of a Volkswagen Beetle, according to the official. They added that their pilots used aircraft with radar that could see through the ice, but still couldn’t find any remnants. 

An Illinois balloon hobby group said one of their small balloons went missing off the coast of Alaska, but added that they could not be sure if their balloon was what the military shot down. 

National Security Council spokesman John Kirby said at a briefing on Friday that no group has claimed any of the three objects that the military downed.

https://thehill.com/policy/national-security/3864205-us-calls-off-search-for-unidentified-aerial-objects-shot-down-over-alaska-lake-huron/

Subsidies boosted Affordable Care Act rolls setting up potential fight

 Health insurance sign-ups through the Affordable Care Act (ACA) jumped by nearly 2 million during the most recent enrollment period, which ended in mid-January, totaling 16.3 million people.  

The gains suggest the program known as Obamacare is going strong, despite repeated efforts by Republicans to kill it.  

It also suggests subsidies provided to the program through two massive pieces of legislation spearheaded by President Biden had an influence. The subsidies were established by the American Rescue Plan in 2021 and subsequently extended through the Inflation Reduction Act. 

“It really speaks to the improved affordability of ACA Marketplace plans. The expanded subsidies made ACA Marketplace plans a whole lot more affordable and attractive for people,” Krutika Amin, associate director at the Kaiser Family Foundation (KFF), told The Hill. 

The potential problem down the road for the Affordable Care Act is that these critical subsidies are set to expire in 2025 and would have to be renewed by Congress in order to continue.

Both the White House and Democrats in Congress have called for the subsidies to be made permanent, but Republicans are likely to oppose those efforts.

That sets up a battle within next year’s race for the White House and the congressional majorities.

Republicans on the House Budget Committee recently proposed cutting these subsidies to help address the nation’s debt. A change like this could impact future enrollment, casting a shadow on the expanded access to health care the Biden administration has included among its hallmark achievements. 

In its proposal, the House Budget Committee suggested capping ACA subsidies to 400 percent of the poverty level and below, essentially returning to the original standards set by the ACA. The panel estimated that “recovering overpayments” could save the government $65 billion. 

Whether a GOP majority would actually move forward with such a proposal is a real question, say some analysts.

“I’m kind of skeptical about this precisely because this is something that the budget committees do every year. It doesn’t represent necessarily something that the Republican majority would support generally speaking. It’s a starting point for some kind of a discussion,” Joseph Antos, a health policy analyst at the conservative think tank American Enterprise Institute, told The Hill.

Antos noted the Republican Study Committee made no mention of reducing ACA premium subsidies in its proposed alternative budget for 2023, with the plan mostly focusing on regulatory changes to the program.

Ending the subsidies would be a politically fraught endeavor, especially with the program’s expanded use and popularity.

“The old saying is that once you’ve handed somebody an entitlement, you can’t take it back. And that’s what the ACA is,” said Antos. “It’s very difficult for a politician to actually take a cut in anything that directly affects voters. It really doesn’t matter whether you think that the people who are benefiting most are more likely to vote Democrat or Republican. It leaves a bad taste in everybody’s mouth.”

Amin from KFF noted that the income limit for subsidies proposed by House Republicans would set a cutoff at a little over $54,000 in 2023. 

“If that does happen, where ACA subsidies are once again capped up to that income level, then some people — particularly middle-income people and older people — will have to pay a lot more for easy marketplace plans,” Amin said. 

Amin gave the example of a 60-year-old individual making about $55,000 annually. With the current subsidies, such an individual would pay about 8 1/2 percent of their income for a Silver health plan, a mid-level plan available through the Marketplace. 

“If the GOP proposal to cap the subsidies … moves forward, the 60-year-old would have to pay over 20 percent of their income on average in some states,” said Amin. 

While he did not touch on this specific proposal, Biden made it clear during his State of the Union address last week he would veto any legislative attempts by Republicans to drastically change the health care landscape, including access to abortion at the federal level and potential cuts to Medicare.

Apart from the subsidies, administration officials and health care stakeholders also attributed the boost in enrollment to concerted efforts on outreach and awareness. 

Liberal health care advocacy group Protect our Care cited the administration’s investment into the ACA’s Navigators program as another reason for the increasing enrollment numbers. Navigators are essentially ACA enrollment advisers who are tasked with raising awareness of Marketplace plans and assist consumers in preparing their applications. 

“The nation’s uninsured rate is at the lowest it has ever been in history,” Protect our Care said in a statement. “We’re finally starting to reach the true potential of the Affordable Care Act, and you see that reflected in the enrollment numbers. The lesson here is that the American people want us to keep pushing these policies forward until we ensure that everyone has the care they need to thrive.” 

A spokesperson for the Centers for Medicare and Medicaid (CMS) echoed these sentiments, saying the level of outreach had risen to an “unprecedented scope and scale” this past year. 

“Enrollment outreach included investments to reach multiple audiences that experience lower access to health care. CMS has partnered with cultural marketing experts, for example, to deliver strong campaigns to African Americans, Spanish and English-speaking Latinos, and Asian American and Pacific Islander communities in multiple languages,” the spokesperson said.

CMS invested nearly $100 million in grant funding to 59 Navigator organizations for this year’s enrollment period, another record amount according to the agency’s spokesperson. 

https://thehill.com/policy/healthcare/3863423-subsidies-have-boosted-affordable-care-acts-enrollment-its-setting-up-a-potential-fight/

Over 60,000 minors to cross dangerous Panama-Colombia jungle gap in 2023, says UN

 A substantial hike in children crossing the Darien jungle - linking Panama with Colombia - is expected this year, the United Nations said on Friday, amid a surge in migrants making the dangerous journey to reach the United States.

By the end of 2023, more than 300,000 migrants are set to have crossed the jungle, over 60,000 of which could be minors, said Diana Romero, an emergency protection specialist at the United Nations children's agency (UNICEF).

"At least 20% (of people using the route) will be children and adolescents," Romero told Reuters, asking families to review the decision due to the perils of such journey.

That would put the flow of minors passing through the Darien up if compared to the 40,438 who entered the country in 2022, according to official data.

In January this year, over 4,800 children and adolescents are recorded to have used the route, seven times more than the same month a year earlier.

Over the last four years, the Darien Gap has gone from being a route for adult migrants to hosting whole families fleeing from poverty, violence and lack of work, Romero said.

Last year, a record 248,000 migrants crossed the Darien Gap, most of them Venezuelans. A new, stricter U.S. migration policy has resulted in many being returned to Panama, where they often cannot afford transportation back to Venezuela.

At least 39 people died in Panama on Wednesday after a bus carrying more than 60 migrants, among several children, fell off a cliff, marking the country's worst known migration accident.

Wednesday's accident highlighted the "need to improve the living conditions" of those looking to migrate, Romero said.

She also said that many of those arriving in Panama said they would not have exposed their children if they had known about the area's dangers before the trip.

https://www.yahoo.com/news/least-60-000-minors-set-013545095.html

China swipes at 'hysterical' U.S. at global security gathering

 China's top diplomat on Saturday accused the United States of violating international norms with "hysterical" behaviour, as a running spat over a suspected Chinese spy balloon bubbled to the fore at a global security conference in Munich.

The comments by Wang Yi further clouded the prospects of a meeting between Wang and U.S. Secretary of State Antony Blinken at the sidelines of the gathering. Asked by Reuters whether he would meet Blinken, Wang later smiled and declined comment.

Wang was speaking on the second day of the annual Munich Security Conference, which this year had so far been dominated by the global response to the Russian invasion of Ukraine as the war grinds towards its second year.

U.S. Vice President Kamala Harris later shot back, saying she was troubled that China had deepened its relationship with Russia since the Feb. 24 invasion and that Chinese support to Russia would undermine the rules-based international order.

The spat over the balloon - which flew over the United States and Canada before being shot down on President Joe Biden's orders, hit already strained relations and at a time when the West is closely watching Beijing's response to the Ukraine war.

"To have dispatched an advanced fighter jet to shoot down a balloon with a missile, such behaviour is unbelievable, almost hysterical," said Wang.

"There are so many balloons all over the world, and various countries have them, so is the United States going to shoot all of them down?," he said.

"We ask the U.S. to show its sincerity and correct its mistakes, face up and resolve this incident, which has damaged Sino-U.S. relations."

The balloon spat had prompted Blinken to postpone a planned visit to Beijing. That Feb. 5-6 trip would have been the first by a U.S. secretary of state to China in five years and was seen by both sides as an opportunity to stabilise ties.

On its part, Washington is hoping to put a "floor" under relations that hit a dangerous low in August with China's reaction to a visit to Taiwan by then-U.S. House Speaker Nancy Pelosi.

THINKING CALMLY

The West has been wary of China's response to the war in Ukraine, with some warning that a Russian victory would colour China's actions towards Taiwan. China has refrained from condemning the war or calling it an "invasion".

"If (Russian President Vladimir) Putin thinks he can wait us out, he is badly mistaken," Harris said in a panel at the gathering of top politicians, military officers and defence industry chiefs and experts at the Munich conference.

"Time is not on his side."

Wang reiterated a call for dialogue and suggested European countries "think calmly" about how to end the war.

Wang also said there were "some forces that seemingly don't want negotiations to succeed, or for the war to end soon," without specifying to whom he was referring.

Russia, which has cast its "special military operation" in Ukraine as an existential battle with an aggressive and arrogant West, on Friday accused the United States of inciting Ukraine to escalate the war by condoning attacks on Crimea.

The Munich conference began on Friday with Ukrainian President Volodymyr Zelenskiy urging Western allies to speed up sending modern weaponry in what he cast as a "David-vs-Goliath" war for freedom against Russia.

On Saturday, European Union chief Ursula von der Leyen outlined plans to speed up giving sorely needed munitions to Ukraine and replenish the bloc's own stocks, while Poland signalled a willingness to send MiG fighter jets to Kyiv.

Germany's Foreign Minister Annalena Baerbock also met Wang at the conference. Berlin has been reviewing its own ties to Beijing since the invasion, wary of its economy's heavy reliance on the Chinese market.

"We discussed intensively yesterday what a just peace would look like," Baerbock said.

"Not that you reward the attacker, the aggressor, but that you stand up for international law and for those who were attacked. China is as a permanent member of the UN Security Council obligated to use its influence to secure world peace."

https://www.yahoo.com/now/china-swipes-hysterical-u-global-125729618.html